4 Influential NFL Football Spreads for Bettors in Week 10

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Week 10 NFL
BetMGM Staff @BETMGM Nov 10, 2021, 4:19 PM

There are 14 intriguing NFL betting spreads to wager on in Week 10, but which ones are the safest bets?

After an unpredictable Week 9, it may be hard for bettors to trust their favorite teams this week. However, I’ve found four NFL football spreads worthy of your faith.

Read on to learn more about which point spread bets stick out this week.

Saints at Titans (-3)

Who would’ve thought the Titans without Derrick Henry would beat down on the Los Angeles Rams like they did last week? Instead, the Titans look as good as ever, even without their MVP-candidate running back.

Tennessee is now 7-1 against the spread football betting in their last eight games. I think that streak continues versus a Saints team that just lost to the Falcons at home.

If 36-year-old Matt Ryan could put up 343 yards and 2 TDs on this Saints defense, I’ll bet that Ryan Tannehill can do even better.

Browns (+1.5) at Patriots

This season, the Patriots have been a surprise. They’re winners of three in a row behind rookie quarterback Mac Jones.

I think their luck could run out on Sunday, though. They have a lot to worry about in this Week 10 NFL game.

At home, the Patriots are only 1-4 this year. On top of that, they’ll be facing a formidable rushing attack from Clevland. Cleveland ranks second in rushing yards per game (160.2). Even if Nick Chubb doesn’t play, D’Ernest Johnson has looked more than capable in his absence.

Cleveland’s run game wouldn’t be as concerning if New England had a stout run defense. But, unfortunately, they’re only middle of the pack in that category, ranking 14th in rush yards allowed per game.

New England is only a slight favorite for this week’s NFL betting because they’re at home. But, with or without Chubb, I think Cleveland is the true favorite.

Panthers at Cardinals (-10)

These teams are trending in opposite directions.

Even without Kyler Murray and DeAndre Hopkins, the Cardinals dismantled the 49ers last week, winning 31-17.

With their returns likely, I expect the full-strength Arizona offense to shred Carolina’s pass defense that allows 6.6 passing yards per attempt. Consider, too, that the Cardinals are 7-2 ATS this season, making them one of the best NFL bets.

Also, we should take every opportunity we can get to bet against Sam Darnold. In his last six games, Darnold has thrown a staggering ten interceptions.

Cheifs at Raiders (+2.5)

This play is more of a bet against the Chiefs than a bet on the Raiders.

Kansas City is the most overvalued team in the league this year, thanks to their big-name stars. People want to believe Mahomes and the Cheifs can return to form, but they can’t football point spreads, going 2-7 ATS this year.

They only have a middle-of-the-road offense, ranking 15th in points per game. They also are fielding one of the worst defenses in the NFL, ranking dead last in opponent yards per play (6.3).

The Raiders haven’t been world-beaters this year, but I think that Derek Carr should be able to get it done on Sunday.

Carr and the Raiders should be able to pick apart the Kansas City defense through the air, as they average the 2nd most passing yards per game (305.1).

Bet On The Best NFL Football Spreads

Do you agree with my picks for these NFL football spreads?

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Our BetMGM authors are sports experts, with a wealth of knowledge of the sports betting industry at all levels. Their coverage includes sports news across players, teams and coaches, providing betting previews and predictions, fun facts and more.

Our BetMGM authors are sports experts, with a wealth of knowledge of the sports betting industry at all levels. Their coverage includes sports news across players, teams and coaches, providing betting previews and predictions, fun facts and more.