49ers vs Packers NFL Betting Odds, Lines & Predictions for Divisional Playoff Round

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BetMGM Betting @BETMGM Jan 21, 2022, 1:25 PM
  • The Packers (13-3) are -5.5 favorites vs the 49ers (9-7)
  • Saturday, January 22, 2022 8:15pm EST on FOX
  • Total (Over/Under): 46.5 points

The Green Bay Packers (13-3) play the San Francisco 49ers (9-7) on Saturday, January 22, 2022 8:15pm EST at Lambeau Field in the Divisional Round of the NFL playoffs.

The Packers are betting favorites in this matchup, with the spread sitting at -5.5 (-110).

The total (Over/Under) is 46.5 points for the game.

Looking to place a bet on this game with a risk-free bet up to $1,000? Bet now on Packers vs 49ers and all NFL games with BetMGM

Where & How to Watch Green Bay Packers vs. San Francisco 49ers, Divisional Playoff Round

  • Game Day: Saturday, January 22, 2022
  • Game Time: 8:15pm EST
  • TV Channel: FOX
  • Location: Green Bay, WI at Lambeau Field

San Francisco 49ers vs. Green Bay Packers Betting Odds & Spread, Divisional Playoff Round

SpreadTotal (O/U)Moneyline
San Francisco 49ers+5.5 -11046.5 -110210
Green Bay Packers -5.5 -11046.5 -110-250

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San Francisco 49ers: Keys to the Game vs. the Green Bay Packers

The 49ers were undefeated (7-0) when not throwing an interception this season — tied for best in NFL; League Avg: .655.

The 49ers were 7-2 (.778) when committing less than 60 yards in penalties this season — tied for 3rd-best in NFL; League Avg: .509.

The 49ers were 6-1 (.857) when intercepting at least 1 pass this season — 4th-best in NFL; League Avg: .633.

The 49ers are 1-9 (.100) when rushing for less than 100 yards since last season — 3rd-worst in NFL; League Avg: .317.

Green Bay Packers: Keys to the Game vs. the San Francisco 49ers

The Packers were 9-2 (.818) when passing for more than 250 yards this season — 2nd-best in NFL; League Avg: .541.

The Packers were 10-1 (.909) when not losing a fumble this season — tied for best in NFL; League Avg: .577.

The Packers were undefeated (11-0) when intercepting at least 1 pass this season — tied for best in NFL; League Avg: .633.

The Packers were 11-1 (.917) when not throwing an interception this season — 4th-best in NFL; League Avg: .655.

Additional Matchup Notes for San Francisco 49ers vs. Green Bay Packers, Divisional Round

Packers RBs rushed for 10 or more yards on just 6.9% of 391 carries this season — second-worst in NFL. The 49ers allowed 10+ yards on just 6.8% of carries to RBs this season — second-best in NFL.

The Packers averaged 38.9 penalty yards per game this season — fifth-best in NFL. The 49ers averaged 36.7 defensive penalty yards per game this season — worst in NFL.

The Packers threw the ball 57.3% of the time in the red zone this season — third-highest in NFL. The 49ers allowed a completion rate of 65.9% when defending in the red zone this season — third-worst in NFL.

The 49ers averaged 61.8 penalty yards per game this season — worst in NFL. The Packers averaged 13.6 offensive penalty yards per game this season — best in NFL.

49ers WRs averaged 7.9 yards after the catch last week — second-best in NFL. The Packers allowed 7.5 yards after catch per reception to WRs last week — fourth-worst in NFL.

49ers RBs have 11 receiving touchdowns since the 2020 season — tied for third-most in NFL. The Packers have allowed 9 receiving touchdowns to RBs since last season — tied for fourth-most in NFL.

Key Injuries for the Green Bay Packers vs. San Francisco 49ers Game, Divisional Round

  • Josiah Deguara (Packers): Concussion, Did Not Participate In Practice
  • Tyler Lancaster (Packers): Back, Limited Participation In Practice
  • Lucas Patrick (Packers): Concussion, Limited Participation In Practice
  • Darnell Savage (Packers): Shoulder, Limited Participation In Practice
  • Vernon Scott (Packers): Hamstring, Limited Participation In Practice
  • Za'Darius Smith (Packers): Back, Did Not Participate In Practice
  • Arik Armstead (49ers): Adductor, Limited Participation In Practice
  • Dre Greenlaw (49ers): Groin, Did Not Participate In Practice
  • Javon Kinlaw (49ers): Knee, Limited Participation In Practice
  • Emmanuel Moseley (49ers): Knee, Limited Participation In Practice
  • Marcell Harris (49ers): Oblique, Limited Participation In Practice

San Francisco 49ers Offense: Important Stats for Divisional Round

The 49ers started 19 drives inside their own 20 yard line in the 4th quarter this season — most in NFL.

The 49ers had an average drive start position from the 18.6 yard line in the 3rd quarter this season — worst in NFL; League Avg: 25.6.

The 49ers started 12 drives inside their own 10 yard line in the 2nd half this season — most in NFL.

The 49ers started 23 drives inside their own 10 yard line this season — most in NFL.

Green Bay Packers Defense: Important Stats for Divisional Round

The Packers threw for 48 TDs last season — most in NFL

The Packers ran successful plays on 57% of rush attempts in the 3rd quarter this season — best in NFL; League Avg: 45%.

The Packers converted first downs on 29 of 78 plays (37%) on 3rd and long last season — 2nd-best in NFL; League Avg: 26%

The Packers ran 54% of their plays in their opponent’s territory in the 1st half last season — best in NFL; League Avg: 44%

San Francisco 49ers Defense: Important Stats for Divisional Round

The 49ers defense did not allow a successful play on any play in the 3rd quarter in Week 18 — best in NFL; League Avg: 42%.

The 49ers defense allowed 6.8 yards from scrimmage per touch (5,229 yards / 771 touches) last season — 2nd-best in NFL; League Avg: 7.5

The 49ers defense allowed an average of 8.5 fantasy points per game as a unit to RBs in the last 4 weeks of the regular season — best in NFL; League Avg: 17.6.

The 49ers defense allowed passes of 20+ yards on 13 of 78 attempts (17%) on 3rd and long this season — worst in NFL; League Avg: 9%.

Green Bay Packers Defense: Important Stats for Divisional Round

The Packers defense allowed rushes of 10+ yards on 20 of 85 carries (23%) in the last 4 weeks of the regular season — worst in NFL; League Avg: 11%.

The Packers defense allowed successful plays on 55% of rush attempts in the 3rd quarter this season — 2nd-worst in NFL; League Avg: 45%.

The Packers defense allowed an average time of possession of 25 min and 56 s this season — lowest in NFL; League Avg: {SetAvgMin:0} min {SetAvgSec:0}s.

The Packers defense had no interceptions (77 pass attempts) in the red zone last season — tied for worst in NFL; League Avg: 39.8

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.