San Francisco 49ers vs Los Angeles Rams NFL Betting Odds, Lines & Predictions for Week 18

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BetMGM Betting @BETMGM Jan 06, 2022, 11:07 PM
  • The Rams (12-4) are -4.5 favorites vs the 49ers (9-7)
  • Sunday, January 9, 2022 4:25pm EST on FOX
  • Total (Over/Under): 44.5 points

The Los Angeles Rams (12-4) play the San Francisco 49ers (9-7) on Sunday, January 9, 2022 4:25pm EST at SoFi Stadium.

The Rams are betting favorites in this matchup, with the spread sitting at -4.5 (-110).

The total (Over/Under) is 44.5 points for the game.

Looking for a risk-free bet up to $1,000? Bet now on Rams vs 49ers and all NFL games with BetMGM

Where & How to Watch Los Angeles Rams vs. San Francisco 49ers, Week 18

  • Game Day: Sunday, January 9, 2022
  • Game Time: 4:25pm EST
  • TV Channel: FOX
  • Location: Inglewood, CA at SoFi Stadium

San Francisco 49ers vs. Los Angeles Rams Betting Odds & Spread, Week 18

SpreadTotal (O/U)Moneyline
San Francisco 49ers+4.5 -11044.5 -110180
Los Angeles Rams -4.5 -11044.5 -110-225

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San Francisco 49ers: Keys to the Game vs. the Los Angeles Rams

The 49ers are undefeated (7-0) when not throwing an interception this season — tied for best in NFL; League Avg: .651.

The 49ers are 6-2 (.750) when committing less than 60 yards in penalties this season — tied for 4th-best in NFL; League Avg: .506.

The 49ers are 2-8 (.200) when converting less than 55% of its red zone chances into touchdowns since last season — tied for 2nd-worst in NFL; League Avg: .418.

The 49ers are 8-2 (.800) when tied at the end of quarter 1 since the 2019 season — best in NFL; League Avg: .490.

Los Angeles Rams: Keys to the Game vs. the San Francisco 49ers

The Rams are 6-0 (1.000) when not throwing an interception this season — tied for best in NFL. The 49ers have intercepted 7 passes this season — tied for third-fewest in NFL.

The Rams are 19-5 (.792) when forcing 1 or more turnovers since the 2020 season — tied for fifth-best in NFL. The 49ers have turned the ball over 50 times since last season — tied for second-most in NFL.

The Rams are 3-4 (.429) when rushing less than 20 times since last season — 3rd-best in NFL; League Avg: .153.

The Rams are undefeated (7-0) when allowing less than 22 points this season — tied for best in NFL; League Avg: .760.

Additional Matchup Notes for San Francisco 49ers vs. Los Angeles Rams, Week 18

Rams TEs have just 35.0 receiving yards per game this season — third-worst in NFL. The 49ers have allowed an average ofjust 32.9 receiving yards per game to TEs this season — second-best in NFL.

The Rams average 37.6 penalty yards per game this season — second-best in NFL. The 49ers averages 36.9 defensive penalty yards per game this season — worst in NFL.

The Rams have thrown the ball 56.9% of the time in the red zone this season — fourth-highest in NFL. The 49ers have allowed a completion rate of 64.5% when defending in the red zone this season — fourth-worst in NFL.

The 49ers average 62.2 penalty yards per game this season — third-worst in NFL. The Rams average 14.2 offensive penalty yards per game this season — best in NFL.

The 49ers have an average drive start position from the 23.6 yard line this season — second-worst in NFL. The Rams have allowed an average drive start position from the 24.3 yard line this season — second-best in NFL.

49ers RBs have been targeted 5 times in the Red Zone since Week 14 — tied for third-most in NFL. The Rams have allowed 1 receiving touchdown when defending in the red zone since Week 14 — tied for fewest in NFL.

Key Injuries for the Los Angeles Rams vs. San Francisco 49ers Game, Week 18

  • Los Angeles Rams - No Injuries Reported
  • San Francisco 49ers - No Injuries Reported

San Francisco 49ers Offense: Important Stats for Week 18

The 49ers have started 18 drives inside their own 20 yard line in the 4th quarter this season — most in NFL.

The 49ers have started 23 drives inside their own 10 yard line this season — most in NFL.

The 49ers have an average drive start position from the 23.6 yard line this season — 2nd-worst in NFL; League Avg: 26.4.

The 49ers have faced a blitz just 10% of the time this season — lowest in NFL; League Avg: 15%.

Los Angeles Rams Offense: Important Stats for Week 18

The Rams have a third down conversion rate of 59% against the blitz this season — 2nd-best in NFL; League Avg: 39%.

The Rams have run successful plays on 59% of pass attempts in the 4th quarter this season — best in NFL; League Avg: 46%.

The Rams have run 28% of their plays in the red zone in the 4th quarter this season — best in NFL; League Avg: 17%.

The Rams have gone three and out on 12% of their drives in the 1st half this season — best in NFL; League Avg: 21%.

San Francisco 49ers Defense: Important Stats for Week 18

The 49ers defense has not allowed a first down on any of their opponents’ 12 rush attempts on 3rd and long this season — tied for best in NFL; League Avg: 22%.

The 49ers defense allowed a third down conversion rate of 17% on 3rd and long last season — best in NFL; League Avg: 27%

The 49ers defense has allowed just 4.6 yards per dropback (730 yards/157 attempts) when targeted at a depth of 1-5 yards this season — best in NFL; League Avg: 5.6.

The 49ers defense allowed 6.8 yards from scrimmage per touch (5,229 yards / 771 touches) last season — 2nd-best in NFL; League Avg: 7.5

Los Angeles Rams Defense: Important Stats for Week 18

The Rams defense has allowed 15 TD passes this season — 2nd-fewest in NFL.

The Rams’ opponents have averaged 39.5 Passing Attempts per TD (592 Pass Attempts/15 Passing TDs) this season — 2nd-best Pass Attempts Per TD rate in NFL; League Avg: 22.7.

The Rams’ opponents have averaged 35.6 Passing Attempts per TD (1,140 Pass Attempts/32 Passing TDs) since last season — best Pass Attempts Per TD rate in NFL; League Avg: 21.7.

The Rams defense allowed just 16.8 points per game to opposing offenses (268 points / 16 games) last season — best in NFL; League Avg: 23.8

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.