After an onslaught of FCS blowouts and a handful of marquee matchups, the second week of college football is officially on the board at BetMGM.
With dozens more games against FCS opponents on tap for this weekend, many teams will play as gargantuan favorites on Saturday.Â
But until those lines are posted – which won’t happen until closer to kickoff – these are the biggest college football spreads available for Week 2:Â
Penn State -24 vs. Temple
Washington -26.5 vs. Utah State
Texas Tech -26.5 vs. Oregon State
Nebraska -29 vs. Bowling Green
USC -30.5 vs. Louisiana
Auburn -32.5 vs. Southern Miss
LSU -35.5 vs. Louisiana Tech
Georgia -41 vs. Western Kentucky
Notre Dame -44.5 vs. Rice
Ole Miss -47.5 vs. Charlotte
Biggest Favorites For College Football Week 2 (2026)
| Favorite Team | Point Spread | Opponent |
|---|---|---|
| Ole Miss | -47.5 | Charlotte |
| Notre Dame | -44.5 | Rice |
| Georgia | -41 | Western Kentucky |
| LSU | -35.5 | Louisiana Tech |
| Auburn | -32.5 | Southern Miss |
| USC | -30.5 | Louisiana |
| Nebraska | -29 | Bowling Green |
| Texas Tech | -26.5 | Oregon State |
| Washington | -26.5 | Utah State |
| Penn State | -24 | Temple |
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