Charlotte vs Ole Miss Prediction, Odds & Best Prop Bets – NCAAF, Week 2

Mississippi head coach Pete Golding walks the sideline against Georgia during the second half of the Sugar Bowl NCAA college football playoff quarterfinal game, Thursday, Jan. 1, 2026, in New Orleans. (AP Photo/Matthew Hinton Hinton)
(AP Photo/Matthew Hinton Hinton)
Odds Boost This Weekend
  • Ole Miss Rebels is a -47.5 point favorite vs. Charlotte 49ers
  • Charlotte vs. Ole Miss Total (Over/Under): 60.5 points
  • TV Channel: ESPN2

Charlotte (0-1) visit Vaught-Hemingway Stadium to take on Ole Miss (1-0) on Sep. 12 in University, MS. Kickoff is scheduled for 7:45 pm.

The Ole Miss Rebels are betting favorites in Week 2, with the spread sitting at -47.5 (-110).

The Charlotte vs. Ole Miss Over/Under is 60.5 total points.

Bet now on Ole Miss Rebels vs Charlotte 49ers & all NCAAF games with BetMGM

Charlotte vs. Ole Miss Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
Charlotte+49 -10860.5 -108+25000
Ole Miss -47.5 -11060.5 -110+1

Charlotte vs Ole Miss Prediction:

The winning team model predicts Ole Miss will win this game with 95.0% confidence, based on game simulations, offensive & defensive matchups and recent game results.

The winning team prediction factors in up-to-date player injuries for both the Charlotte 49ers and the Ole Miss Rebels, key player performances this season and recent team trends.

Charlotte vs Ole Miss Spread Prediction:

Based on recent against-the-spread trends, the model predicts Charlotte will cover the spread with 66.4% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


Bet now on Ole Miss Rebels vs Charlotte 49ers and all games with BetMGM


  • Charlotte has hit the 1Q Game Total Over in 8 of their last 10 games (+5.60 Units / 46% ROI)
  • Charlotte have covered the Spread in their last 4 away games (+4.00 Units / 91% ROI)
  • Charlotte has hit the Game Total Over in 7 of their last 11 games (+2.60 Units / 22% ROI)
  • Charlotte has hit the Team Total Under in 3 of their last 4 away games (+1.95 Units / 41% ROI)
  • Charlotte has hit the 1H Game Total Under in 2 of their last 4 away games (+0.90 Units / 20% ROI)
  • Ole Miss has hit the Moneyline in 10 of their last 12 games (+9.55 Units / 28% ROI)
  • Ole Miss has hit the Team Total Over in 10 of their last 14 games (+5.48 Units / 33% ROI)
  • Ole Miss has hit the 1H Moneyline in 10 of their last 13 games (+5.45 Units / 6% ROI)
  • Ole Miss have covered the 1H Spread in 9 of their last 13 games (+4.15 Units / 27% ROI)
  • Ole Miss has hit the 1H Game Total Under in 6 of their last 9 games at home (+2.65 Units / 25% ROI)

Charlotte Against the Spread (ATS) Record

Charlotte 49ers is 0-1 against the spread this college football season (-1.08 Units / -100% ROI).

  • Charlotte is 0-1 when betting on the Moneyline for -16.5 Units / -100% ROI
  • Charlotte is 1-0 when betting the Over for +1 Units / 92.59% ROI
  • Charlotte is 0-1 when betting the Under for -1.12 Units / -100% ROI

Ole Miss Against the Spread (ATS) Record

Ole Miss Rebels is 0-1 against the spread this college football season (-1.1 Units / -100% ROI).

  • Ole Miss is 1-0 when betting on the Moneyline for +1 Units / 40% ROI
  • Ole Miss is 1-0 when betting the Over for +1 Units / 90.91% ROI
  • Ole Miss is 0-1 when betting the Under for -1.1 Units / -100% ROI

Charlotte: Keys to the Game vs. Ole Miss

Charlotte is winless (0-10) when making less than 5 explosive passes in a game since the 2024 season– T-worst in FBS; Average: .466

Charlotte is 5-1 (.833) when in a one score game since the 2024 season– T-6th-best in FBS; Average: .504

Charlotte was 2-6 (.250) when their opponent committed less than 60 yards in penalties in the 2023 season– T-12th-worst among Non-Power Conference Teams; Average: .479

Charlotte was 2-4 (.333) when having a turnover margin within one of the opposing team in the 2023 season– T-30th-worst in FBS; Average: .533

Ole Miss: Keys to the Game vs. Charlotte

Ole Miss was 10-2 (.833) when converting 55% or more of its red zone chances into touchdowns last season– 21st-best in FBS; Average: .624

Ole Miss was 9-2 (.818) when allowing less than 50% of third down conversion opportunities last season– T-24th-best in FBS; Average: .602

Ole Miss was 10-3 (.769) when allowing less than 5 yards per rush last season– T-33rd-best in FBS; Average: .632

Ole Miss was 7-2 (.778) when having a turnover margin within one of the opposing team last season– 14th-best among Power Conference Teams; Average: .578

Matchup Notes for Charlotte vs. Ole Miss

Ole Miss’s QBs threw for 4,700 passing yards in 15 games (313.3 YPG) last season — 3rd-best among FBS teams. Charlotte’s defense allowed 271.7 passing yards per game last season — 7th-worst among FBS defenses.

Ole Miss’s offense threw for 4,700 passing yards in 15 games (313.3 YPG) last season — 3rd-best among FBS offenses. Charlotte’s defense allowed 271.7 passing yards per game last season — 7th-worst among FBS defenses.

Ole Miss’s QBs threw for 4,700 passing yards in 15 games (313.3 YPG) last season — 3rd-best among FBS teams. Charlotte’s defense allowed 271.7 passing yards per game last season — 3rd-worst among NonP5 defenses.

Charlotte’s RBs rushed for 877 yards on 251 carries (just 3.5 YPC) last season — T-2nd-worst among FBS RBs. Ole Miss’s defense allowed 4.1 YPC last season — T-4th-worst among SEC defenses.

Charlotte’s RBs had just 15.6 receiving yards per game last season — 29th-worst among FBS RBs. Ole Miss’s defense allowed just 198.9 receiving yards per game last season — 5th-best among SEC defenses.

Charlotte’s RBs had just 0.0 receiving touchdowns per game last season — T-worst among FBS RBs. Ole Miss’s defense allowed just 1.1 receiving touchdowns per game last season — T-3rd-best among SEC defenses.

Charlotte Offensive Stats & Trends

Charlotte WRs averaged 18.4 yards per reception (2,114 yards/115 catches) last season– 2nd-best among FBS Teams; Average: 13.4

Charlotte RBs rushed for 2 TDs on 251 carries (125.5 Carries Per TD) last season– worst Carries Per TD among FBS Teams; Average: 22.9

Charlotte WRs averaged 26.5 yards per reception (212 yards/8 catches) with 4-6 yards to go last season– best among FBS Teams; Average: 12.2

Charlotte WRs averaged 20.0 yards per reception (600 yards/30 catches) in the 4th quarter last season– 2nd-best among FBS Teams; Average: 13.2

Charlotte RBs fumbled 8 times last season– T-most among FBS Teams

Ole Miss Offensive Stats & Trends

Ole Miss Skill Players averaged 20.2 yards per reception (1,053 yards/52 catches) in the 4th quarter last season– best among FBS Teams; Average: 11.8

Ole Miss Skill Players averaged 20.2 yards per reception (1,053 yards/52 catches) in the 4th quarter last season– best among SEC Teams; Average: 12.2

Ole Miss averaged 20.2 yards per completion (1,053 yards/52 completions) in the 4th quarter last season– best among FBS Offenses; Average: 11.7

Ole Miss Skill Players averaged 20.2 yards per reception (1,053 yards/52 catches) in the 4th quarter last season– best among Power Conference Teams; Average: 11.9

Ole Miss averaged 20.2 yards per reception (1,053 yards/52 catches) in the 4th quarter last season– best among FBS Offenses; Average: 11.7

Charlotte Defensive Stats & Trends

Charlotte did not record a sack (42 pass attempts) in the Red Zone last season– T-worst among Non-Power Conference Teams; Average: 15.8

Charlotte did not record a sack (42 pass attempts) in the Red Zone last season– T-worst in FBS; Average: 16.2

Charlotte tackled opponents for a loss on just 4 of 69 rushing attempts (6% TFL%) in the Red Zone last season– T-2nd-worst among Non-Power Conference Teams; Average: 14%.

Charlotte allowed 42 TDs in the Red Zone last season– 2nd-most in FBS

Charlotte tackled opponents for a loss on just 4 of 69 rushing attempts (6% TFL%) in the Red Zone last season– T-3rd-worst in FBS; Average: 14%.

Ole Miss Defensive Stats & Trends

Ole Miss tackled opponents for a loss on 112 of 456 rushing attempts (25% TFL%) last season– best in the SEC; Average: 17%.

Ole Miss allowed 7 rushing TDs on 456 carries (65.1 Carries Per TD) last season– 2nd-best among Power Conference Teams; Average: 25.5

Ole Miss allowed 7 rushing TDs on 456 carries (65.1 Carries Per TD) last season– 2nd-best in FBS; Average: 23.2

Ole Miss tackled opponents for a loss on 112 of 456 rushing attempts (25% TFL%) last season– best in FBS; Average: 16%.

Ole Miss allowed 7 rushing TDs on 456 carries (65.1 Carries Per TD) last season– best in the SEC; Average: 29.9


Bet now on Ole Miss Rebels vs Charlotte 49ers and all games with BetMGM


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