Georgia Southern vs Clemson Prediction, Odds & Best Prop Bets – NCAAF, Week 2

Clemson head coach Dabo Swinney questions an official after a play during the first half of the Cheez-It Bowl NCAA college football game against Iowa State in Orlando, Fla., Wednesday, Dec. 29, 2021. Clemson had won six straight ACC titles heading into last season, but started 4-3 and fell out of contention for a seventh. The team rebounded, though, to win their last six games — the longest current win streak among Power Five teams — and look to a slimmer, more confident quarterback DJ Uiagalelei to start a new championship run. (AP Photo/Phelan M. Ebenhack, File)
(AP Photo/Phelan M. Ebenhack)
Sportsbook Promos This Week
  • Clemson Tigers is a -20.5 point favorite vs. Georgia Southern Eagles
  • Georgia Southern vs. Clemson Total (Over/Under): 55.5 points
  • TV Channel: ACCN

Georgia Southern (1-0) visit Memorial Stadium to take on Clemson (0-1) on Sep. 12 in Clemson, SC. Kickoff is scheduled for 7:30 pm.

The Clemson Tigers are betting favorites in Week 2, with the spread sitting at -20.5 (-110).

The Georgia Southern vs. Clemson Over/Under is 55.5 total points.

Bet now on Clemson Tigers vs Georgia Southern Eagles & all NCAAF games with BetMGM

Georgia Southern vs. Clemson Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
Georgia Southern+20.5 -10855.5 -108+950
Clemson -20.5 -11055.5 -110-1400

Georgia Southern vs Clemson Prediction:

The winning team model predicts Clemson will win this game with 89.0% confidence, based on game simulations, offensive & defensive matchups and recent game results.

The winning team prediction factors in up-to-date player injuries for both the Georgia Southern Eagles and the Clemson Tigers, key player performances this season and recent team trends.

Georgia Southern vs Clemson Spread Prediction:

Based on recent against-the-spread trends, the model predicts Clemson will cover the spread with 65.6% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


Bet now on Clemson Tigers vs Georgia Southern Eagles and all games with BetMGM


  • Georgia Southern has hit the Moneyline in 8 of their last 12 games (+6.59 Units / 8% ROI)
  • Georgia Southern has hit the 1H Moneyline in their last 4 away games (+5.70 Units / 92% ROI)
  • Georgia Southern has hit the Game Total Under in their last 5 away games (+5.00 Units / 92% ROI)
  • Georgia Southern has hit the Team Total Under in their last 5 away games (+5.00 Units / 84% ROI)
  • Georgia Southern have covered the Spread in 8 of their last 12 games (+4.70 Units / 36% ROI)
  • Clemson has hit the Team Total Under in 5 of their last 6 games at home (+3.85 Units / 56% ROI)
  • Clemson has hit the Game Total Under in 2 of their last 3 games at home (+2.00 Units / 61% ROI)
  • Clemson has hit the 1Q Game Total Under in 3 of their last 4 games at home (+1.85 Units / 40% ROI)
  • Clemson has hit the 1H Game Total Over in 7 of their last 12 games (+1.40 Units / 10% ROI)
  • Clemson have covered the 1H Spread in 2 of their last 3 games at home (+0.85 Units / 26% ROI)

Georgia Southern Against the Spread (ATS) Record

Georgia Southern Eagles is 1-0 against the spread this college football season (+1 Units / 90.91% ROI).

  • Georgia Southern is 1-0 when betting on the Moneyline for +1 Units / 2.22% ROI
  • Georgia Southern is 0-1 when betting the Over for -1.1 Units / -100% ROI
  • Georgia Southern is 1-0 when betting the Under for +1 Units / 90.91% ROI

Clemson Against the Spread (ATS) Record

Clemson Tigers is 0-1 against the spread this college football season (-1.1 Units / -100% ROI).

  • Clemson is 0-1 when betting on the Moneyline for -1 Units / -100% ROI
  • Clemson is 1-0 when betting the Over for +1 Units / 90.91% ROI
  • Clemson is 0-1 when betting the Under for -1.1 Units / -100% ROI

Georgia Southern: Keys to the Game vs. Clemson

Georgia Southern was 7-4 (.636) when sacking the QB less than 3 times last season– T-28th-best in FBS; Average: .429

Georgia Southern was 7-4 (.636) when sacking the QB less than 3 times last season– T-9th-best among Non-Power Conference Teams; Average: .388

Georgia Southern was 6-2 (.750) when allowing less than 50% of third down conversion opportunities last season– T-12th-best among Non-Power Conference Teams; Average: .552

Georgia Southern was 3-1 (.750) when not losing a fumble last season– T-12th-best among Non-Power Conference Teams; Average: .533

Clemson: Keys to the Game vs. Georgia Southern

Clemson was 9-3 (.750) when converting 55% or more of its red zone chances into touchdowns last season– T-31st-best in FBS; Average: .624

Clemson was undefeated (7-0) when allowing less than 5 yards per rush last season– T-best among Power Conference Teams; Average: .647

Clemson was 8-2 (.800) when allowing less than 50% of third down conversion opportunities last season– T-27th-best in FBS; Average: .602

Clemson was 9-3 (.750) when rushing at least 4 yards in a play 10 or more times last season– T-32nd-best in FBS; Average: .575

Matchup Notes for Georgia Southern vs. Clemson

Clemson’s QBs threw for 3,406 passing yards in 13 games (262.0 YPG) last season — 31st-best among FBS teams. Georgia Southern’s defense allowed 238.8 passing yards per game last season — 34th-worst among FBS defenses.

Clemson’s WRs had 200.9 receiving yards per game last season — 4th-best among ACC WRs. Georgia Southern’s defense allowed 238.8 receiving yards per game last season — 34th-worst among FBS defenses.

Clemson’s WRs had 200.9 receiving yards per game last season — 24th-best among FBS WRs. Georgia Southern’s defense allowed 184.1 receiving yards per game to WRs last season — 18th-worst among FBS defenses.

Georgia Southern’s WRs had 204.3 receiving yards per game last season — 21st-best among FBS WRs. Clemson’s defense allowed 251.6 receiving yards per game last season — 17th-worst among FBS defenses.

Georgia Southern’s WRs averaged 25.5 targets per game last season — T-14th-highest among FBS WRs. Clemson’s defense allowed 14.0 receptions per game to WRs last season — 22nd-worst among FBS defenses.

Georgia Southern’s WRs had 204.3 receiving yards per game last season — 21st-best among FBS WRs. Clemson’s defense allowed 183.8 receiving yards per game to WRs last season — 19th-worst among FBS defenses.

Georgia Southern Offensive Stats & Trends

Georgia Southern’s WRs had 204.3 receiving yards per game last season — 21st-best among FBS WRs. Clemson’s defense allowed 251.6 receiving yards per game last season — 17th-worst among FBS defenses.

Georgia Southern’s WRs averaged 25.5 targets per game last season — T-14th-highest among FBS WRs. Clemson’s defense allowed 14.0 receptions per game to WRs last season — 22nd-worst among FBS defenses.

Georgia Southern’s WRs had 204.3 receiving yards per game last season — 21st-best among FBS WRs. Clemson’s defense allowed 183.8 receiving yards per game to WRs last season — 19th-worst among FBS defenses.

Georgia Southern’s WRs had 205 receptions in 13 games (15.8 per game) last season — 18th-best among FBS WRs. Clemson’s defense allowed 14.0 receptions per game to WRs last season — 22nd-worst among FBS defenses.

Georgia Southern has 305 receptions in 14 games (21.8 per game) since the 2024 season — 33rd-best among FBS skill players. Clemson’s defense has allowed 22.6 receptions per game since the 2024 season — 3rd-worst among ACC defenses.

Clemson Offensive Stats & Trends

Clemson Skill Players averaged a touchdown every 3.8 receptions (23 Rec/6 TDs) in the Red Zone last season– T-5th-worst Receptions Per TD among FBS Teams; Average: 2.1

Clemson WRs averaged a touchdown every 6.0 receptions (12 Rec/2 TDs) in the Red Zone last season– 6th-worst Receptions Per TD among FBS Teams; Average: 2.0

Clemson WRs averaged a touchdown every 6.0 receptions (12 Rec/2 TDs) in the Red Zone last season– 3rd-worst Receptions Per TD among Power Conference Teams; Average: 2.0

Clemson threw 6 TDs on 48 pass attempts (one TD every 8.0 Pass Attempts) in the Red Zone last season– 6th-worst among FBS Offenses; Average: 3.7

Clemson RBs averaged 8.9 yards from scrimmage per touch (277 yards / 31 touches) on 3rd and short last season– best among FBS Teams; Average: 4.4

Georgia Southern Defensive Stats & Trends

Georgia Southern allowed rushes of 10 or more yards on 102 of 499 carries (20%) last season– 2nd-worst among Non-Power Conference Teams; Average: 13%

Georgia Southern allowed opponents to rush for 20+ yards on 33 of their 499 carries (7%) last season– worst among Non-Power Conference Teams; Average: 4%

Georgia Southern allowed opponents to rush for 20+ yards on 33 of their 499 carries (7%) last season– 2nd-worst in FBS; Average: 3%

Georgia Southern averaged a sack every 34.5 pass attempts (414 Pass Attempts/12 Sacks) last season– 3rd-worst among Non-Power Conference Teams; Average: 15.2

Georgia Southern averaged a sack every 34.5 pass attempts (414 Pass Attempts/12 Sacks) last season– 3rd-worst in FBS; Average: 14.7

Clemson Defensive Stats & Trends

Clemson allowed a Completion Pct of just 14% (2 completions/14 attempts) on 3rd and short last season– best among Power Conference Teams; Average: 62%

Clemson allowed a Completion Pct of just 14% (2 completions/14 attempts) on 3rd and short last season– 2nd-best in FBS; Average: 63%

Clemson allowed opponents to rush for 20+ yards on 30 of their 477 carries (6%) last season– worst among Power Conference Teams; Average: 3%

Clemson allowed first downs on 14% of pass attempts on 3rd and short last season– 3rd-best in FBS; Average: 51%

Clemson has allowed a Completion Pct of just 25% (7 completions/28 attempts) on 3rd and short since the 2024 season– best among Power Conference Teams; Average: 61%


Bet now on Clemson Tigers vs Georgia Southern Eagles and all games with BetMGM


More College Football Betting at BetMGM

College football betting is available at the online sportsbook throughout the season.

Whether you’re a first-time bettor checking out the best sportsbook promos, a casual fan betting on Indiana football national championship odds, Michigan football odds, or Ohio State odds this week, or a longtime diehard breaking down trends for live betting, there are entertainment options for everyone.

Visit the sportsbook today to place a college football bet online!

The content provided in this blog is intended for entertainment purposes only. All views and opinions expressed are the authors and reflect their individual perspectives on sports, betting, and related topics. This content should not be considered professional betting advice or the official views of BetMGM LLC. Please gamble responsibly. If you or someone you know is experiencing issues related to gambling, seek help from a licensed health professional. This blog is not liable for any losses, damages, or consequences resulting from betting activities.

About the Author Read More @BETMGM

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.