Indiana vs. Oregon: Odds for CFP Semifinals at the Peach Bowl

Indiana wide receiver Omar Cooper Jr. (3) points to the sidelines during the first half of an NCAA college football game against Oregon, Saturday, Oct. 11, 2025, in Eugene, Ore.
(AP Photo/Lydia Ely)
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No. 1 Indiana continues its march toward an undefeated season with a semifinal game against Oregon at the Peach Bowl in Atlanta.

Unsurprisingly, the Hoosiers will play as the betting favorite, according to BetMGMโ€™s college football odds market.ย 

Indiana vs. Oregon Odds

  • Point Spread: Indiana -3.5
  • Moneyline: Indiana -175ย  |ย  Oregon +145
  • Total: 48.5

Indiana vs. Oregon: Peach Bowl Playoff Game

Indiana and Oregon have already played once this year โ€“ a Week 7 affair that the Hoosiers won by 10 points in Eugene. Oregon was a 6.5-point favorite.

This time, Indiana is the favorite, and the game will be on the East Coast instead of out west.

Bettors have been reticent to side with the Hoosiers this postseason, and head coach Curt Cignetti just keeps proving people wrong. Indiana is 5-0 straight up and ATS this season in games with a point spread shorter than 10 points.ย 

In other words, when the game is expected to be competitive, Indiana wins and covers.

Oregon has looked like a true national championship contender during this CFP, but the Ducks havenโ€™t yet faced a team with the skill and balance that Indiana brings to the field.

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About the Author Read More @chaseakiddy

Chase Kiddy is a writer for BetMGM and co-host of The Lion's Edge, an NFL and college football podcast available on Spotify, Apple Podcasts, and everywhere else. He has also written for a number of print and online outlets, including the Richmond Times-Dispatch, Washington Post, Daily News-Record, and HERO Sports. His first novel, Cave Paintings, is in development.

Chase Kiddy is a writer for BetMGM and co-host of The Lion's Edge, an NFL and college football podcast available on Spotify, Apple Podcasts, and everywhere else. He has also written for a number of print and online outlets, including the Richmond Times-Dispatch, Washington Post, Daily News-Record, and HERO Sports. His first novel, Cave Paintings, is in development.