Iowa St. vs Ohio Prediction, Odds & Best Prop Bets – NCAAF, Week 3

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Ohio quarterback Kurtis Rourke (7) during an NCAA college football game, Saturday, Sept. 17, 2022, in Ames, Iowa.
(AP Photo/Justin Hayworth)
BetMGM Betting @BETMGM Sep 16, 2023, 11:13 AM
  • Iowa St. is a -3 point favorite vs. Ohio
  • Total (Over/Under): 42.5 points
  • Watch the game on ESPN Networks

The Iowa State Cyclones visit Frank Solich Field at Peden Stadium to take on the Ohio Bobcats on Sep. 16. Kickoff is scheduled for 12:00pm EDT in Athens.

Iowa St. is a betting favorite in Week 3, with the spread sitting at -2.5 (-105).

The Iowa St. vs. Ohio Over/Under is 42.5 total points.

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Iowa St. vs. Ohio Odds, Spread, Over/Under for Week 3

SpreadTotal (O/U)Moneyline
Iowa St.-2.5 -10542.5 -110-130
Ohio +2.5 -11542.5 -110+110

Iowa St. vs Ohio Prediction for Week 3

Based on recent trends, the winning team model predicts Iowa State will win this game with 54.2% confidence.

Iowa St. vs Ohio Spread Prediction for Week 3

Based on recent against-the-spread trends, the model predicts Ohio will cover the spread with 77.0% confidence.

Both predictions factor in up-to-date player injuries for both Iowa St. and Ohio, plus offensive & defensive matchups, recent games and key player performances this season.


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  • Iowa State has hit the 1H Game Total Under in 7 of their last 8 games (+5.90 Units / 67% ROI)
  • Iowa State has hit the Game Total Under in 9 of their last 12 games (+5.70 Units / 43% ROI)
  • Iowa State has hit the Team Total Under in 6 of their last 8 games (+3.70 Units / 41% ROI)
  • Iowa State has hit the 1Q Game Total Under in 5 of their last 6 games (+3.65 Units / 45% ROI)
  • Iowa State has hit the 1Q Moneyline in 2 of their last 6 games (+2.20 Units / 29% ROI)
  • Ohio has hit the 1H Moneyline in 8 of their last 10 games (+7.10 Units / 49% ROI)
  • Ohio has hit the Moneyline in 10 of their last 14 games (+6.85 Units / 27% ROI)
  • Ohio have covered the 1H Spread in 8 of their last 10 games (+5.80 Units / 52% ROI)
  • Ohio has hit the Team Total Over in their last 4 games (+4.00 Units / 85% ROI)
  • Ohio have covered the Spread in 9 of their last 15 games (+3.50 Units / 21% ROI)

Best Iowa St. Player Prop Bets Today

We’ve highlighted some favorite college football player prop bets for Iowa St. players for Week 3, looking at profitable historical betting trends:

  • Hunter Dekkers has hit the Passing Yards Over in 8 of his last 11 games (+4.60 Units / 36% ROI)
  • Hunter Dekkers has hit the TD Passes Under in 5 of his last 6 games (+3.80 Units / 46% ROI)
  • Jaylin Noel has hit the Receiving Yards Over in 3 of his last 5 games (+0.80 Units / 14% ROI)

Iowa St. Against the Spread (ATS) Record

Iowa St. is 1-1 against the spread this college football season (-0.1 Units / -4.55% ROI).

  • Iowa St. is 1-1 when betting on the Moneyline for +0 Units / 0% ROI
  • Iowa St. is 0-2 when betting the Over for -2.2 Units / -100% ROI
  • Iowa St. is 2-0 when betting the Under for +2 Units / 90.91% ROI

Ohio Against the Spread (ATS) Record

Ohio is 1-2 against the spread this college football season (-1.2 Units / -36.36% ROI).

  • Ohio is 1-1 when betting on the Moneyline for +0.5 Units / 25% ROI
  • Ohio is 0-3 when betting the Over for -3.3 Units / -100% ROI
  • Ohio is 3-0 when betting the Under for +3 Units / 90.91% ROI

Iowa St.: Keys to the Game vs. Ohio

Iowa State is winless (0-8) when the opposing team rushes more than 30 times since the 2022 season– tied for worst among Power 5 Teams; Average: .412

Iowa State is winless (0-8) when allowing 22 or more points since the 2021 season– tied for worst in FBS; Average: .290

Iowa State is winless (0-4) when allowing an average of more than 5 yards on first down plays since the 2022 season– tied for worst among Power 5 Teams; Average: .442

Iowa State is 3-12 (.200) when in a one score game since the 2021 season– tied for 4th-worst among Power 5 Teams; Average: .494

Ohio: Keys to the Game vs. Iowa St.

Ohio is undefeated (7-0) when allowing less than 5 yards per rush since the 2022 season– tied for best in FBS; Average: .584

Ohio is 2-9 (.154) when making less than 5 explosive passes in a game since the 2021 season– 15th-worst in FBS; Average: .410

Ohio was undefeated (7-0) when allowing less than 5 yards per rush in the 2022 season– tied for best in FBS; Average: .587

Matchup Notes for Iowa St. vs. Ohio

Ohio’s offense has thrown for 20 or more yards on 12.5% of 559 attempts since the 2022 season — 29th-best among FBS offenses. Iowa State’s defense allowed 20+ yards on just 8.2% of attempts since the 2022 season — worst among Big 12 defenses.

Ohio’s QBs has thrown for 609 passing yards in 3 games (just 203.0 YPG) this season — tied for 30th-worst among FBS teams. Iowa State’s defense has allowed just 162.5 passing yards per game this season — best among Big 12 defenses.

Ohio’s WRs has gained 371 yards on 37 receptions (just 10.0 YPR) this season — tied for 13th-worst among FBS WRs. Iowa State’s defense has allowed just 10.2 Yards Per Reception this season — tied for second-best among Big 12 defenses.

Iowa State’s WRs has gained 212 yards on 26 receptions (just 8.2 YPR) this season — worst among Power 5 WRs. Ohio’s defense has allowed just 8.6 Yards Per Reception this season — 12th-best among FBS defenses.

Iowa State has gained 319 yards on 37 receptions (just 8.6 YPR) this season — seventh-worst among FBS skill players. Ohio’s defense has allowed just 8.6 Yards Per Reception this season — 12th-best among FBS defenses.

Iowa State has gained 319 yards on 37 receptions (just 8.6 YPR) this season — worst among Big 12 skill players. Ohio’s defense has allowed just 8.6 Yards Per Reception this season — fifth-best among NonP5 defenses.

Iowa St. Offensive Stats & Trends

Iowa State Skill Players were targeted 135 times on 3rd down in the 2022 season– most among Power 5 Teams

Iowa State’s WRs has gained 212 yards on 26 receptions (just 8.2 YPR) this season — worst among Power 5 WRs. Ohio’s defense has allowed just 8.6 Yards Per Reception this season — 12th-best among FBS defenses.

Iowa State has gained 319 yards on 37 receptions (just 8.6 YPR) this season — seventh-worst among FBS skill players. Ohio’s defense has allowed just 8.6 Yards Per Reception this season — 12th-best among FBS defenses.

Iowa State WRs were targeted 100 times on 3rd down in the 2022 season– most among FBS Teams

Iowa State has gained 319 yards on 37 receptions (just 8.6 YPR) this season — worst among Big 12 skill players. Ohio’s defense has allowed just 8.6 Yards Per Reception this season — fifth-best among NonP5 defenses.

Ohio Offensive Stats & Trends

Ohio’s offense has thrown for 20 or more yards on 12.5% of 559 attempts since the 2022 season — 29th-best among FBS offenses. Iowa State’s defense allowed 20+ yards on just 8.2% of attempts since the 2022 season — worst among Big 12 defenses.

Ohio’s QBs has thrown for 609 passing yards in 3 games (just 203.0 YPG) this season — tied for 30th-worst among FBS teams. Iowa State’s defense has allowed just 162.5 passing yards per game this season — best among Big 12 defenses.

Ohio’s WRs has gained 371 yards on 37 receptions (just 10.0 YPR) this season — tied for 13th-worst among FBS WRs. Iowa State’s defense has allowed just 10.2 Yards Per Reception this season — tied for second-best among Big 12 defenses.

Ohio QBs had 18 completions for 20 or more yards on 3rd down in the 2022 season– most among FBS Teams

Ohio QBs have 22 completions for 20 or more yards on 3rd down since last season– 2nd most among FBS Teams

Iowa State Cyclones Defensive Stats & Trends

Iowa State has tackled opponents for a loss on 13 of 42 rushing attempts (31% TFL%) on 3rd and short since last season– tied for 3rd best in FBS; Average: 12%.

Iowa State has tackled opponents for a loss on 13 of 42 rushing attempts (31% TFL%) on 3rd and short since last season– 3rd best among Power 5 Teams; Average: 11%.

Iowa State has allowed a Completion Pct of just 36% (19 completions/53 attempts) on 3rd and long since last season– best in FBS; Average: 54%

Iowa State has tackled opponents for a loss on 19 of 80 rushing attempts (24% TFL%) on 3rd and short since the 2021 season– 3rd best in FBS; Average: 11%.

Iowa State has allowed 20 rushing TDs on 914 carries (45.7 Carries Per TD) since the 2021 season– 4th best in FBS; Average: 24.3

Ohio Bobcats Defensive Stats & Trends

Ohio allowed 170 first down receptions in the 2022 season– most in FBS

Ohio allowed 3,881 Passing Yards in the 2022 season– most in FBS

Ohio has tackled opponents for a loss on 9 of 31 rushing attempts (29% TFL%) on 3rd and short since last season– 5th best in FBS; Average: 12%.

Ohio allowed 170 first down receptions in the 2022 season– most among Non-Power 5 Teams

Ohio has allowed 216 first down receptions since last season– most among Non-Power 5 Teams


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.