Iowa State opens the 2026 football season against Southeast Missouri at home. The Cyclones went 8-4 last year, including 5-4 in the Big 12.
Current 2026 Win Total Odds
Iowa State’s win total for 2026 is 5.5.
The Cyclones have won at least seven games the past three years. They most recently failed to win seven games in 2022 (4-8).
2026 Iowa State Cyclones Football Schedule
Iowa State’s non-conference schedule begins in Week 1 with a home game vs. Southeast Missouri. The Cyclones’ road opener is Sept. 12, a non-conference game vs. Iowa.
Iowa State’s first conference game is a Sept. 26 home matchup vs. Utah.
Non-Conference Matchups
- Sept. 5: vs. Southeast Missouri
- Sept. 12: at Iowa
- Sept. 19: vs. Bowling Green
Of Iowa State’s non-conference opponents, Iowa won the most games in 2025; the Hawkeyes went 9-4.
Big 12 Conference Matchups
- Sept. 26: vs. Utah
- Oct. 3: vs. West Virginia
- Oct. 9: at BYU
- Oct. 24: at Arizona
- Oct. 31: vs. Oklahoma State
- Nov. 7: at Baylor
- Nov. 14: vs. Cincinnati
- Nov. 20: at UCF
- Nov. 28: vs. Kansas State
Of Iowa State’s conference opponents, BYU won the most games; the Cougars went 12-2, including 8-1 in the Big 12.
2025 Iowa State Football Results
Iowa State went 8-4 during the 2025 regular season and did not play in a bowl game.
- Aug. 23: vs. Kansas State* – Win (24-21)
- Aug. 30: vs. South Dakota – Win (55-7)
- Sept. 6: vs. Iowa – Win (16-13)
- Sept. 13: at Arkansas State – Win (24-16)
- Sept. 27: vs. Arizona – Win (39-14)
- Oct. 4: at Cincinnati – Loss (38-30)
- Oct. 11: at Colorado – Loss (24-17)
- Oct. 25: vs. BYU – Loss (41-27)
- Nov. 1: vs. Arizona State – Loss (24-19)
- Nov. 8: at TCU – Win (20-17)
- Nov. 22: vs. Kansas – Win (38-14)
- Nov. 29: at Oklahoma State – Win (20-13)
*neutral site
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