Iowa vs Vanderbilt Prediction, Odds & Best Prop Bets โ€“ ReliaQuest Bowl

Vanderbilt head coach Clark Lea argues a call in the first half of an NCAA college football game against Florida Saturday, Nov. 19, 2022, in Nashville, Tenn.
(AP Photo/Mark Humphrey)
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  • Vanderbilt is a -5.5 point favorite vs. Iowa
  • Iowa vs. Vanderbilt Total (Over/Under): 46.5 points
  • TV Channel: ESPN

Iowa (8-4) visit Raymond James Stadium to take on Vanderbilt (10-2) on Dec. 31 in Tampa, FL. Kickoff is scheduled for 12:00pm EST.

Vanderbilt is a betting favorite in the ReliaQuest Bowl, with the spread sitting at -5.5 (-105).

The Iowa vs. Vanderbilt Over/Under is 46.5 total points.

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Iowa vs. Vanderbilt Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
Iowa+5.5 -11546.5 -110165
Vanderbilt -5.5 -10546.5 -110-200

Iowa vs Vanderbilt Prediction:

The winning team model predicts Vanderbilt will win this game with 65.0% confidence, based on game simulations, offensive & defensive matchups and recent game results.

This winning team prediction factors in up-to-date player injuries for both Iowa and Vanderbilt, key player performances this season and recent team trends.

Iowa vs Vanderbilt Spread Prediction:

Based on recent against-the-spread trends, the model predicts Vanderbilt will cover the spread with 50.7% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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  • Iowa has hit the 1H Game Total Over in their last 6 away games (+6.00 Units / 86% ROI)
  • Iowa has hit the 1H Moneyline in 7 of their last 12 games (+4.15 Units / 6% ROI)
  • Iowa have covered the Spread in 8 of their last 13 games (+3.64 Units / 26% ROI)
  • Iowa has hit the Team Total Over in 7 of their last 10 games (+3.55 Units / 30% ROI)
  • Iowa has hit the 1Q Game Total Over in 7 of their last 12 games (+2.70 Units / 21% ROI)
  • Vanderbilt have covered the Spread in 10 of their last 12 games (+7.80 Units / 59% ROI)
  • Vanderbilt has hit the Team Total Over in 10 of their last 12 games (+7.70 Units / 56% ROI)
  • Vanderbilt has hit the Moneyline in 9 of their last 11 games (+7.55 Units / 11% ROI)
  • Vanderbilt has hit the Game Total Over in 7 of their last 9 games (+4.80 Units / 48% ROI)
  • Vanderbilt has hit the 1H Game Total Over in 8 of their last 12 games (+3.45 Units / 25% ROI)

Iowa Against the Spread (ATS) Record

Iowa is 8-3 against the spread this college football season (+4.74 Units / 36.16% ROI).

  • Iowa is 6-4 when betting on the Moneyline for +2 Units / 8.64% ROI
  • Iowa is 5-7 when betting the Over for -2.7 Units / -20.45% ROI
  • Iowa is 7-5 when betting the Under for +1.5 Units / 11.34% ROI

Vanderbilt Against the Spread (ATS) Record

Vanderbilt iss 10-2 against the spread this college football season (+7.8 Units / 59.09% ROI).

  • Vanderbilt is 9-2 when betting on the Moneyline for +7.55 Units / 10.52% ROI
  • Vanderbilt is 8-4 when betting the Over for +3.6 Units / 27.27% ROI
  • Vanderbilt is 4-8 when betting the Under for -4.8 Units / -36.36% ROI

Iowa: Keys to the Game vs. Vanderbilt

Iowa was 5-1 (.833) when making 7 or more explosive plays last season– T-23rd-best in FBS; Average: .628

Iowa was 8-2 (.800) when allowing less than 5 yards per rush last season– T-26th-best in FBS; Average: .632

Iowa was 2-5 (.286) when having a turnover margin within one of the opposing team last season– T-4th-worst among Power Conference Teams; Average: .578

Iowa was 1-5 (.167) when throwing at least 1 interception last season– T-5th-worst among Power Conference Teams; Average: .443

Vanderbilt: Keys to the Game vs. Iowa

Vanderbilt has allowed 12 first down receptions in the Red Zone this season– most in the SEC

Vanderbilt allowed passes of 20+ yards on 10 of 52 attempts (19%) on 3rd and long last season– worst in the SEC; Average: 9%

Vanderbilt has intercepted 4 of 340 attempts (85.0 pass attempts per int.) this season– 2nd-worst in the SEC; Average: 39.0

Vanderbilt tackled opponents for a loss on just 2 of 39 rushing attempts (5% TFL%) on 3rd and short last season– 2nd-worst in the SEC; Average: 11%.

Vanderbilt has allowed 13 TD passes in the Red Zone this season– most in the SEC

Matchup Notes for Iowa vs. Vanderbilt

Vanderbilt has allowed 12 first down receptions in the Red Zone this season– most in the SEC

Vanderbilt allowed passes of 20+ yards on 10 of 52 attempts (19%) on 3rd and long last season– worst in the SEC; Average: 9%

Vanderbilt has intercepted 4 of 340 attempts (85.0 pass attempts per int.) this season– 2nd-worst in the SEC; Average: 39.0

Vanderbilt tackled opponents for a loss on just 2 of 39 rushing attempts (5% TFL%) on 3rd and short last season– 2nd-worst in the SEC; Average: 11%.

Vanderbilt has allowed 13 TD passes in the Red Zone this season– most in the SEC

Iowa was 5-1 (.833) when making 7 or more explosive plays last season– T-23rd-best in FBS; Average: .628

Iowa was 8-2 (.800) when allowing less than 5 yards per rush last season– T-26th-best in FBS; Average: .632

Iowa was 2-5 (.286) when having a turnover margin within one of the opposing team last season– T-4th-worst among Power Conference Teams; Average: .578

Iowa was 1-5 (.167) when throwing at least 1 interception last season– T-5th-worst among Power Conference Teams; Average: .443

Iowa Offensive Stats & Trends

Iowa was 5-1 (.833) when making 7 or more explosive plays last season– T-23rd-best in FBS; Average: .628

Iowa was 8-2 (.800) when allowing less than 5 yards per rush last season– T-26th-best in FBS; Average: .632

Iowa was 2-5 (.286) when having a turnover margin within one of the opposing team last season– T-4th-worst among Power Conference Teams; Average: .578

Iowa was 1-5 (.167) when throwing at least 1 interception last season– T-5th-worst among Power Conference Teams; Average: .443

Vanderbilt Offensive Stats & Trends

Vanderbilt has allowed 12 first down receptions in the Red Zone this season– most in the SEC

Vanderbilt allowed passes of 20+ yards on 10 of 52 attempts (19%) on 3rd and long last season– worst in the SEC; Average: 9%

Vanderbilt has intercepted 4 of 340 attempts (85.0 pass attempts per int.) this season– 2nd-worst in the SEC; Average: 39.0

Vanderbilt tackled opponents for a loss on just 2 of 39 rushing attempts (5% TFL%) on 3rd and short last season– 2nd-worst in the SEC; Average: 11%.

Vanderbilt has allowed 13 TD passes in the Red Zone this season– most in the SEC

Iowa Defensive Stats & Trends

Iowa was 5-1 (.833) when making 7 or more explosive plays last season– T-23rd-best in FBS; Average: .628

Iowa was 8-2 (.800) when allowing less than 5 yards per rush last season– T-26th-best in FBS; Average: .632

Iowa was 2-5 (.286) when having a turnover margin within one of the opposing team last season– T-4th-worst among Power Conference Teams; Average: .578

Iowa was 1-5 (.167) when throwing at least 1 interception last season– T-5th-worst among Power Conference Teams; Average: .443

Vanderbilt Defensive Stats & Trends

Vanderbilt has allowed 12 first down receptions in the Red Zone this season– most in the SEC

Vanderbilt allowed passes of 20+ yards on 10 of 52 attempts (19%) on 3rd and long last season– worst in the SEC; Average: 9%

Vanderbilt has intercepted 4 of 340 attempts (85.0 pass attempts per int.) this season– 2nd-worst in the SEC; Average: 39.0

Vanderbilt tackled opponents for a loss on just 2 of 39 rushing attempts (5% TFL%) on 3rd and short last season– 2nd-worst in the SEC; Average: 11%.

Vanderbilt has allowed 13 TD passes in the Red Zone this season– most in the SEC


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