Jacksonville State vs Louisville Prediction, Odds & Best Prop Bets โ€“ NCAAF, Week 2

FILE - Louisville head coach Jeff Brohm shouts instructions to his team during the first half of an NCAA college football game in Louisville, Ky., Saturday, Sept. 23, 2023. Louisville enters without Jack Plummer, who led Jeff Brohm's first-year program to its first ACC title game berth. (AP Photo/Timothy D. Easley, FIle)
(AP Photo/Timothy D. Easley)
  • Louisville is a -28 point favorite vs. Jacksonville State
  • Jacksonville State vs. Louisville Total(Over/Under): 58.5 points
  • TV Channel: ESPN+

The Jacksonville State Gamecocks 0-1 visit L&N Federal Credit Union Stadium to take on the Louisville Cardinals 1-0 on Sep. 7 in Louisville, KY. Kickoff is scheduled for 3:30pm EDT.

Louisville is a betting favorite in Week 2, with the spread sitting at -28 (-110).

The Jacksonville State vs. Louisville Over/Under is 58.5 total points.

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Jacksonville State vs. Louisville Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
Jacksonville State+28 -11058.5 -110+
Louisville -28 -11058.5 -110+

Jacksonville State vs Louisville Prediction:

The winning team model predicts Louisville will win this game with 95.0% confidence, based on game simulations, offensive & defensive matchups and recent game results.

Jacksonville State vs Louisville Spread Prediction:

Based on recent against-the-spread trends, the model predicts Jacksonville State will cover the spread with 89.6% confidence.

Both predictions factor in up-to-date player injuries for both Jacksonville State and Louisville and key player performances this season.


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  • Jacksonville State has hit the 1Q Game Total Over in their last 4 away games (+4.00 Units / 79% ROI)
  • Jacksonville State has hit the Game Total Over in 5 of their last 6 away games (+3.90 Units / 59% ROI)
  • Jacksonville State has hit the Moneyline in 7 of their last 12 games (+2.75 Units / 13% ROI)
  • Jacksonville State have covered the Spread in 3 of their last 5 away games (+0.80 Units / 15% ROI)
  • Louisville has hit the 1Q Moneyline in 7 of their last 12 games (+7.25 Units / 30% ROI)
  • Louisville have covered the 1Q Spread in their last 6 games at home (+6.15 Units / 92% ROI)
  • Louisville has hit the 1H Moneyline in 5 of their last 6 games at home (+5.00 Units / 23% ROI)
  • Louisville have covered the 1H Spread in 6 of their last 7 games at home (+4.95 Units / 63% ROI)
  • Louisville have covered the Spread in 6 of their last 8 games at home (+3.85 Units / 44% ROI)

We’ve highlighted some favorite college football player prop bets for Jacksonville State players, looking at profitable historical betting trends:

Best Jacksonville State Player Prop Bets Today

  • Anwar Lewis has hit the Rushing Yards Under in his last game (+1.00 Units / 80% ROI)

Top NCAAF player prop bets for Louisville players, looking at profitable historical betting trends:

Best Louisville Player Prop Best Bets Today

  • No trends found

Jacksonville State Against the Spread (ATS) Record

Jacksonville State was 0-1 against the spread last college football season (-1.1 Units / -100% ROI).

  • Jacksonville State was 0-1 when betting on the Moneyline for -1.65 Units / -100% ROI
  • Jacksonville State was 1-0 when betting the Over for +1 Units / 90.91% ROI
  • Jacksonville State was 0-1 when betting the Under for -1.1 Units / -100% ROI

Louisville Against the Spread (ATS) Record

Louisville is 1-0 against the spread this college football season (+1 Units / 86.96% ROI).

  • Louisville was 8-4 when betting on the Moneyline for +0.3 Units / 0.77% ROI
  • Louisville was 1-0 when betting the Over for +1 Units / 90.91% ROI
  • Louisville was 0-1 when betting the Under for -1.1 Units / -100% ROI

Jacksonville State: Keys to the Game vs. Louisville

Jacksonville State is 8-3 (.667) when committing less than 60 yards in penalties since the 2022 season– T-2nd-best among Non-Power Conference Teams; Average: .362

Jacksonville State was 8-1 (.800) when they have committed less than 60 yards in penalties in the 2023 season– 2nd-best among Non-Power Conference Teams; Average: .378

Jacksonville State is 7-2 (.778) when making 7 or more explosive plays since the 2022 season– T-8th-best in FBS; Average: .536

Jacksonville State was undefeated (5-0) when scoring 22 or more points in the 2023 season– 12th-best among Non-Power Conference Teams; Average: .554

Louisville: Keys to the Game vs. Jacksonville State

Louisville is 9-1 (.818) when not throwing an interception since the 2022 season– T-13th-best in FBS; Average: .594

Louisville is 14-3 (.700) when allowing less than 3 sacks since the 2022 season– 7th-best among Power Conference Teams; Average: .456

Louisville is 15-3 (.750) when allowing less than 3 sacks since the 2022 season– 13th-best in FBS; Average: .538

Louisville is 10-2 (.714) when not losing a fumble since the 2022 season– T-21st-best in FBS; Average: .500

Matchup Notes for Jacksonville State vs. Louisville

Louisville’s RBs averaged 10.6 yards after the catch last season — 12th-best among FBS RBs. Jacksonville State’s defense allowed 9.8 RAC to RBs last season — T-22nd-worst among FBS defenses.

Louisville’s RBs had 2 rushing touchdowns per game last season — T-8th-best among FBS RBs. Jacksonville State’s defense has allowed just 1.1 rushing touchdowns per game last season — T-31st-best among FBS defenses.

Louisville’s RBs gained 556 yards on 53 receptions (10.5 YPR) last season — 12th-best among FBS RBs. Jacksonville State’s defense allowed 9.8 Yards Per Reception to RBs last season — T-22nd-worst among FBS defenses.

Jacksonville State’s offense threw for 2,223 passing yards in 13 games (just 171.0 YPG) last season — 17th-worst among FBS offenses. Louisville’s defense allowed 222.4 passing yards per game last season — 4th-worst among ACC defenses.

Jacksonville State’s QBs threw for 2,223 passing yards in 13 games (just 171.0 YPG) last season — 19th-worst among FBS teams. Louisville’s defense allowed 222.4 passing yards per game last season — 4th-worst among ACC defenses.

Jacksonville State had 181 receptions in 13 games (just 13.9 per game) last season — 15th-worst among FBS skill players. Louisville’s defense allowed just 16.8 receptions per game last season — T-33rd-best among FBS defenses.

Jacksonville State Offensive Stats & Trends

Jacksonville State’s offense threw for 2,223 passing yards in 13 games (just 171.0 YPG) last season — 17th-worst among FBS offenses. Louisville’s defense allowed 222.4 passing yards per game last season — 4th-worst among ACC defenses.

Jacksonville State TEs have caught just 2 of 7 passes (29% Reception Pct) in the 4th quarter since the 2022 season– 2nd-worst among FBS Teams; Average: 64%

Jacksonville State’s QBs threw for 2,223 passing yards in 13 games (just 171.0 YPG) last season — 19th-worst among FBS teams. Louisville’s defense allowed 222.4 passing yards per game last season — 4th-worst among ACC defenses.

Jacksonville State QBs rushed for 575 yards on 1st down in the 2023 season– 2nd-most among FBS Teams

Jacksonville State WRs have averaged a touchdown every 4.0 receptions (8 Rec/2 TDs) in the Red Zone since the 2022 season– T-4th-worst Receptions Per TD among FBS Teams; Average: 2.0

Louisville Offensive Stats & Trends

Louisville’s RBs averaged 10.6 yards after the catch last season — 12th-best among FBS RBs. Jacksonville State’s defense allowed 9.8 RAC to RBs last season — T-22nd-worst among FBS defenses.

Louisville RBs averaged 7.1 yards from scrimmage per touch (1,604 yards / 225 touches) on 1st down in the 2023 season– 4th-best among FBS Teams; Average: 5.3

Louisville RBs have averaged 5.9 Yards per Carry (4,566 yards/772 carries) since the 2022 season– T-3rd-best among FBS Teams; Average: 5.0

Louisville RBs averaged 162.9 rushing yards per game (2,280/14) in the 2023 season– 12th-best among FBS Teams; Average: 125.0

Louisville RBs had 8 receptions for 20 or more yards in the 2023 season– T-4th-most among FBS Teams

Jacksonville State Gamecocks Defensive Stats & Trends

Jacksonville State has allowed first downs on 16% of rush attempts since the 2022 season– 2nd-best among Non-Power Conference Teams; Average: 23%

Jacksonville State has allowed first downs on 16% of rush attempts since the 2022 season– 2nd-best in FBS; Average: 23%

Jacksonville State allowed rushes of 10 or more yards on just 38 of 520 carries (7%) in the 2023 season– 2nd-best among Non-Power Conference Teams; Average: 14%

Jacksonville State allowed first downs on 15% of rush attempts in the 2023 season– best among Non-Power Conference Teams; Average: 23%

Jacksonville State allowed rushes of 10 or more yards on just 38 of 520 carries (7%) in the 2023 season– 3rd-best in FBS; Average: 13%

Louisville Cardinals Defensive Stats & Trends

Louisville has sacked opposing QBs on 11% of pass attempts (85/801) since the 2022 season– 3rd-best in FBS; Average: 7%

Louisville has tackled opponents for a loss on 23 of 103 rushing attempts (22% TFL%) in the Red Zone since the 2022 season– best among Power Conference Teams; Average: 15%.

Louisville has tackled opponents for a loss on 192 of 937 rushing attempts (20% TFL%) since the 2022 season– 7th-best in FBS; Average: 16%.

Louisville has sacked opposing QBs on 11% of pass attempts (85/801) since the 2022 season– T-3rd-best among Power Conference Teams; Average: 7%

Louisville has tackled opponents for a loss on 23 of 103 rushing attempts (22% TFL%) in the Red Zone since the 2022 season– 5th-best in FBS; Average: 15%.


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