- Ole Miss Rebels is a -7 point favorite vs. Louisville Cardinals
- Louisville vs. Ole Miss Total (Over/Under): 55.5 points
- TV Channel: ABC
Louisville (0-0) visit Nissan Stadium to take on Ole Miss (0-0) on Sep. 6 in Nashville, TN. Kickoff is scheduled for 7:30 pm.
The Ole Miss Rebels are betting favorites in Week 1, with the spread sitting at -7 (-105).
The Louisville vs. Ole Miss Over/Under is 55.5 total points.
Bet now on Ole Miss Rebels vs Louisville Cardinals & all NCAAF games with BetMGM
Louisville vs. Ole Miss Odds, Spread, Over/Under:
| Spread | Total (O/U) | Moneyline | |
| Louisville | +7 -115 | 55.5 -108 | +220 |
| Ole Miss | -7 -105 | 55.5 -110 | -275 |
Louisville vs Ole Miss Prediction:
The winning team model predicts Ole Miss will win this game with 62.4% confidence, based on game simulations, offensive & defensive matchups and recent game results.
This winning team prediction factors in up-to-date player injuries for both Louisville Cardinals and Ole Miss Rebels, key player performances this season and recent team trends.
Louisville vs Ole Miss Spread Prediction:
Based on recent against-the-spread trends, the model predicts Ole Miss will cover the spread with 54.9% confidence.
This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.
Bet now on Ole Miss Rebels vs Louisville Cardinals and all games with BetMGM
Louisville Best Bets Today
- Louisville has hit the Team Total Under in 6 of their last 7 games (+4.80 Units / 61% ROI)
- Louisville has hit the Moneyline in 3 of their last 4 away games (+4.40 Units / 60% ROI)
- Louisville has hit the 1H Game Total Under in 8 of their last 12 games (+3.40 Units / 25% ROI)
- Louisville has hit the Game Total Under in their last 3 away games (+3.00 Units / 91% ROI)
- Louisville has hit the 1Q Game Total Over in 3 of their last 4 away games (+2.10 Units / 51% ROI)
Ole Miss Best Bets Today
- Ole Miss has hit the Moneyline in 10 of their last 12 games (+9.55 Units / 27% ROI)
- Ole Miss has hit the 1Q Moneyline in 7 of their last 8 games (+6.75 Units / 43% ROI)
- Ole Miss has hit the 1H Moneyline in 11 of their last 14 games (+6.45 Units / 6% ROI)
- Ole Miss has hit the Team Total Over in their last 5 games (+5.00 Units / 83% ROI)
- Ole Miss have covered the Spread in 8 of their last 12 games (+3.65 Units / 28% ROI)
Louisville: Keys to the Game vs. Ole Miss
Louisville was 9-2 (.818) when allowing less than 5 yards per rush last season– T-21st-best in FBS; Average: .632
Louisville was 6-2 (.750) when sacking the QB less than 3 times last season– T-12th-best in FBS; Average: .429
Louisville was 8-2 (.800) when averaging more than 5 yards on first down plays last season– T-26th-best in FBS; Average: .604
Louisville was 5-1 (.833) when intercepting at least 1 pass last season– T-24th-best in FBS; Average: .668
Ole Miss: Keys to the Game vs. Louisville
Ole Miss was 7-2 (.778) when having a turnover margin within one of the opposing team last season– 14th-best among Power Conference Teams; Average: .578
Ole Miss was 10-3 (.769) when making 7 or more explosive plays last season– 33rd-best in FBS; Average: .628
Ole Miss was 9-2 (.818) when averaging more than 5 yards on first down plays last season– T-20th-best in FBS; Average: .604
Ole Miss was 9-2 (.818) when averaging more than 5 yards on first down plays last season– T-10th-best among Power Conference Teams; Average: .632
Matchup Notes for Louisville vs. Ole Miss
Ole Miss’s TEs gained 783 yards on 54 receptions (14.5 YPR) last season — 2nd-best among SEC TEs. Louisville’s defense allowed just 10.1 Yards Per Reception last season — 2nd-best among ACC defenses.
Ole Miss’s WRs gained 3,679 yards on 248 receptions (14.8 YPR) last season — T-3rd-best among SEC WRs. Louisville’s defense allowed just 10.1 Yards Per Reception last season — 2nd-best among ACC defenses.
Ole Miss’s TEs gained 783 yards on 54 receptions (14.5 YPR) last season — 2nd-best among SEC TEs. Louisville’s defense allowed just 10.1 Yards Per Reception last season — T-5th-best among P5 defenses.
Louisville’s offense threw for 20 or more yards on just 8.0% of 414 attempts last season — 21st-worst among FBS offenses. Ole Miss’s defense allowed 20+ yards on just 7.9% of attempts last season — T-3rd-best among SEC defenses.
Louisville’s offense threw for 20 or more yards on just 8.0% of 414 attempts last season — 21st-worst among FBS offenses. Ole Miss’s defense allowed 20+ yards on just 7.9% of attempts last season — T-23rd-best among FBS defenses.
Louisville’s WRs had just 0.9 receiving touchdowns per game last season — T-4th-worst among ACC WRs. Ole Miss’s defense allowed just 1.1 receiving touchdowns per game last season — T-20th-best among FBS defenses.
Louisville Offensive Stats & Trends
Louisville’s offense threw for 20 or more yards on just 8.0% of 414 attempts last season — 21st-worst among FBS offenses. Ole Miss’s defense allowed 20+ yards on just 7.9% of attempts last season — T-3rd-best among SEC defenses.
Louisville’s offense threw for 20 or more yards on just 8.0% of 414 attempts last season — 21st-worst among FBS offenses. Ole Miss’s defense allowed 20+ yards on just 7.9% of attempts last season — T-23rd-best among FBS defenses.
Louisville RBs fumbled 8 times last season– T-most among FBS Teams
Louisville RBs averaged 10.2 yards from scrimmage per touch (214 yards / 21 touches) on 3rd and short last season– 2nd-best among FBS Teams; Average: 4.5
Louisville RBs averaged 9.1 Yards per Carry (335 yards/37 carries) in close and late situations last season– 2nd-best among FBS Teams; Average: 5.2
Ole Miss Offensive Stats & Trends
Ole Miss Skill Players averaged 20.2 yards per reception (1,053 yards/52 catches) in the 4th quarter last season– best among Power Conference Teams; Average: 11.9
Ole Miss Skill Players averaged 20.2 yards per reception (1,053 yards/52 catches) in the 4th quarter last season– best among FBS Teams; Average: 11.8
Ole Miss QBs had 42 completions for 20 or more yards on 1st down last season– most among FBS Teams
Ole Miss WRs averaged 21.6 yards per reception (801 yards/37 catches) in the 4th quarter last season– best among Power Conference Teams; Average: 13.3
Ole Miss averaged 20.2 yards per completion (1,053 yards/52 completions) in the 4th quarter last season– best among FBS Offenses; Average: 11.7
Louisville Defensive Stats & Trends
Louisville tackled opponents for a loss on just 4 of 61 rushing attempts (7% TFL%) in the Red Zone last season– 4th-worst among Power Conference Teams; Average: 15%.
Louisville allowed passes of 40+ yards on just 2 of 409 attempts (1%) last season– T-2nd-best in FBS; Average: 2%
Louisville allowed just 10.1 yards per completion (2,454 yards/242 completions) last season– T-7th-best in FBS; Average: 11.5
Louisville allowed first downs on 17% of pass attempts in close and late situations last season– 4th-best among Power Conference Teams; Average: 31%
Louisville allowed a Completion Pct of 91% (10 completions/11 attempts) on 3rd and short last season– 4th-worst among Power Conference Teams; Average: 62%
Ole Miss Defensive Stats & Trends
Ole Miss allowed 7 rushing TDs on 456 carries (65.1 Carries Per TD) last season– 2nd-best in FBS; Average: 23.2
Ole Miss tackled opponents for a loss on 112 of 456 rushing attempts (25% TFL%) last season– best in the SEC; Average: 17%.
Ole Miss tackled opponents for a loss on 112 of 456 rushing attempts (25% TFL%) last season– best among Power Conference Teams; Average: 16%.
Ole Miss tackled opponents for a loss on 15 of 51 rushing attempts (29% TFL%) in the Red Zone last season– 2nd-best in FBS; Average: 15%.
Ole Miss tackled opponents for a loss on 112 of 456 rushing attempts (25% TFL%) last season– best in FBS; Average: 16%.
Bet now on Ole Miss Rebels vs Louisville Cardinals and all games with BetMGM
More College Football Betting at BetMGM
College football betting is available at the online sportsbook throughout the season.
Whether youโre a first-time bettor checking out the best sportsbook promos, a casual fan betting on Indiana football national championship odds, Michigan football odds, or Ohio State odds this week, or a longtime diehard breaking down trends for live betting, there are entertainment options for everyone.
Visit the sportsbook today to place a college football bet online!
The content provided in this blog is intended for entertainment purposes only. All views and opinions expressed are the authors and reflect their individual perspectives on sports, betting, and related topics. This content should not be considered professional betting advice or the official views of BetMGM LLC. Please gamble responsibly. If you or someone you know is experiencing issues related to gambling, seek help from a licensed health professional. This blog is not liable for any losses, damages, or consequences resulting from betting activities.






