- Louisville is a -10.5 point favorite vs. Virginia Tech
- Louisville vs. Virginia Tech Total (Over/Under): 53.5 points
- TV Channel: CW
Louisville (6-1) visit Lane Stadium to take on Virginia Tech (3-5) on Nov. 1 in Blacksburg, VA. Kickoff is scheduled for 3:00pm EDT.
Louisville is a betting favorite in Week 10, with the spread sitting at -10.5 (-110).
The Louisville vs. Virginia Tech Over/Under is 53.5 total points.
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Louisville vs. Virginia Tech Odds, Spread, Over/Under:
| Spread | Total (O/U) | Moneyline | |
| Louisville | -10.5 -110 | 53.5 -102 | -425 |
| Virginia Tech | +10.5 -110 | 53.5 -118 | 325 |
Louisville vs Virginia Tech Prediction:
The winning team model predicts Louisville will win this game with 65.2% confidence, based on game simulations, offensive & defensive matchups and recent game results.
This winning team prediction factors in up-to-date player injuries for both Louisville and Virginia Tech, key player performances this season and recent team trends.
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Louisville Best Bets Today
- Louisville has hit the 1H Moneyline in 4 of their last 5 away games (+5.45 Units / 36% ROI)
- Louisville have covered the Spread in 5 of their last 6 away games (+3.90 Units / 59% ROI)
- Louisville has hit the Game Total Over in 4 of their last 6 away games (+1.80 Units / 27% ROI)
- Louisville has hit the 1Q Game Total Over in 4 of their last 6 away games (+1.70 Units / 25% ROI)
- Louisville have covered the 1H Spread in 4 of their last 6 away games (+1.65 Units / 23% ROI)
Virginia Tech Best Bets Today
- Virginia Tech has hit the Team Total Under in 7 of their last 8 games (+5.80 Units / 63% ROI)
- Virginia Tech has hit the 1Q Moneyline in 6 of their last 7 games at home (+5.00 Units / 18% ROI)
- Virginia Tech have covered the 1Q Spread in 6 of their last 8 games at home (+4.05 Units / 45% ROI)
- Virginia Tech has hit the 1H Game Total Over in 5 of their last 8 games at home (+2.90 Units / 32% ROI)
- Virginia Tech has hit the 1Q Game Total Under in 4 of their last 8 games at home (+1.80 Units / 18% ROI)
Louisville Against the Spread (ATS) Record
Louisville is 2-5 against the spread this college football season (-3.5 Units / -45.45% ROI).
- Louisville is 6-1 when betting on the Moneyline for +6.05 Units / 5.7% ROI
- Louisville is 4-3 when betting the Over for +0.7 Units / 9.09% ROI
- Louisville is 3-4 when betting the Under for -1.4 Units / -18.18% ROI
Virginia Tech Against the Spread (ATS) Record
Virginia Tech iss 2-6 against the spread this college football season (-4.6 Units / -52.27% ROI).
- Virginia Tech is 2-5 when betting on the Moneyline for -3.55 Units / -33.33% ROI
- Virginia Tech is 4-4 when betting the Over for -0.4 Units / -4.57% ROI
- Virginia Tech is 4-4 when betting the Under for -0.45 Units / -5.08% ROI
Louisville: Keys to the Game vs. Virginia Tech
Louisville is undefeated (6-0) when rushing at least 4 yards in a play 10 or more times this season– T-best in FBS; Average: .603
Louisville was 8-3 (.727) when rushing at least 4 yards in a play 10 or more times last season– 35th-best in FBS; Average: .575
Louisville was 6-2 (.750) when sacking the QB less than 3 times last season– T-12th-best in FBS; Average: .429
Louisville is 11-2 (.846) when sacking the QB less than 3 times since the 2024 season– 4th-best in FBS; Average: .436
Virginia Tech: Keys to the Game vs. Louisville
Virginia Tech RBs averaged 8.3 yards from scrimmage per touch (150 yards / 18 touches) on 3rd and short last season– 3rd-best among FBS Teams; Average: 4.4
Virginia Tech’s offense has thrown for 1,515 passing yards in 8 games (just 189.4 YPG) this season — 32nd-worst among FBS offenses. Louisville’s defense has allowed just 181.0 passing yards per game this season — 21st-best among FBS defenses.
Virginia Tech’s TEs has 20 receptions in 8 games (just 2.5 per game) this season — 2nd-worst among ACC TEs. Louisville’s defense has allowed just 16.9 receptions per game this season — T-29th-best among FBS defenses.
Virginia Tech’s offense has thrown for 1,515 passing yards in 8 games (just 189.4 YPG) this season — 32nd-worst among FBS offenses. Louisville’s defense has allowed just 181.0 passing yards per game this season — 2nd-best among ACC defenses.
Virginia Tech have just 189.5 receiving yards per game this season — 2nd-worst among ACC skill players. Louisville’s defense has allowed just 181.0 receiving yards per game this season — 21st-best among FBS defenses.
Matchup Notes for Louisville vs. Virginia Tech
Virginia Tech RBs averaged 8.3 yards from scrimmage per touch (150 yards / 18 touches) on 3rd and short last season– 3rd-best among FBS Teams; Average: 4.4
Virginia Tech’s offense has thrown for 1,515 passing yards in 8 games (just 189.4 YPG) this season — 32nd-worst among FBS offenses. Louisville’s defense has allowed just 181.0 passing yards per game this season — 21st-best among FBS defenses.
Virginia Tech’s TEs has 20 receptions in 8 games (just 2.5 per game) this season — 2nd-worst among ACC TEs. Louisville’s defense has allowed just 16.9 receptions per game this season — T-29th-best among FBS defenses.
Virginia Tech’s offense has thrown for 1,515 passing yards in 8 games (just 189.4 YPG) this season — 32nd-worst among FBS offenses. Louisville’s defense has allowed just 181.0 passing yards per game this season — 2nd-best among ACC defenses.
Virginia Tech have just 189.5 receiving yards per game this season — 2nd-worst among ACC skill players. Louisville’s defense has allowed just 181.0 receiving yards per game this season — 21st-best among FBS defenses.
Louisville is undefeated (6-0) when rushing at least 4 yards in a play 10 or more times this season– T-best in FBS; Average: .603
Louisville was 8-3 (.727) when rushing at least 4 yards in a play 10 or more times last season– 35th-best in FBS; Average: .575
Louisville was 6-2 (.750) when sacking the QB less than 3 times last season– T-12th-best in FBS; Average: .429
Louisville is 11-2 (.846) when sacking the QB less than 3 times since the 2024 season– 4th-best in FBS; Average: .436
Louisville Offensive Stats & Trends
Louisville is undefeated (6-0) when rushing at least 4 yards in a play 10 or more times this season– T-best in FBS; Average: .603
Louisville was 8-3 (.727) when rushing at least 4 yards in a play 10 or more times last season– 35th-best in FBS; Average: .575
Louisville was 6-2 (.750) when sacking the QB less than 3 times last season– T-12th-best in FBS; Average: .429
Louisville is 11-2 (.846) when sacking the QB less than 3 times since the 2024 season– 4th-best in FBS; Average: .436
Virginia Tech Offensive Stats & Trends
Virginia Tech RBs averaged 8.3 yards from scrimmage per touch (150 yards / 18 touches) on 3rd and short last season– 3rd-best among FBS Teams; Average: 4.4
Virginia Tech’s offense has thrown for 1,515 passing yards in 8 games (just 189.4 YPG) this season — 32nd-worst among FBS offenses. Louisville’s defense has allowed just 181.0 passing yards per game this season — 21st-best among FBS defenses.
Virginia Tech’s TEs has 20 receptions in 8 games (just 2.5 per game) this season — 2nd-worst among ACC TEs. Louisville’s defense has allowed just 16.9 receptions per game this season — T-29th-best among FBS defenses.
Virginia Tech’s offense has thrown for 1,515 passing yards in 8 games (just 189.4 YPG) this season — 32nd-worst among FBS offenses. Louisville’s defense has allowed just 181.0 passing yards per game this season — 2nd-best among ACC defenses.
Virginia Tech have just 189.5 receiving yards per game this season — 2nd-worst among ACC skill players. Louisville’s defense has allowed just 181.0 receiving yards per game this season — 21st-best among FBS defenses.
Louisville Defensive Stats & Trends
Louisville is undefeated (6-0) when rushing at least 4 yards in a play 10 or more times this season– T-best in FBS; Average: .603
Louisville was 8-3 (.727) when rushing at least 4 yards in a play 10 or more times last season– 35th-best in FBS; Average: .575
Louisville was 6-2 (.750) when sacking the QB less than 3 times last season– T-12th-best in FBS; Average: .429
Louisville is 11-2 (.846) when sacking the QB less than 3 times since the 2024 season– 4th-best in FBS; Average: .436
Virginia Tech Defensive Stats & Trends
Virginia Tech RBs averaged 8.3 yards from scrimmage per touch (150 yards / 18 touches) on 3rd and short last season– 3rd-best among FBS Teams; Average: 4.4
Virginia Tech’s offense has thrown for 1,515 passing yards in 8 games (just 189.4 YPG) this season — 32nd-worst among FBS offenses. Louisville’s defense has allowed just 181.0 passing yards per game this season — 21st-best among FBS defenses.
Virginia Tech’s TEs has 20 receptions in 8 games (just 2.5 per game) this season — 2nd-worst among ACC TEs. Louisville’s defense has allowed just 16.9 receptions per game this season — T-29th-best among FBS defenses.
Virginia Tech’s offense has thrown for 1,515 passing yards in 8 games (just 189.4 YPG) this season — 32nd-worst among FBS offenses. Louisville’s defense has allowed just 181.0 passing yards per game this season — 2nd-best among ACC defenses.
Virginia Tech have just 189.5 receiving yards per game this season — 2nd-worst among ACC skill players. Louisville’s defense has allowed just 181.0 receiving yards per game this season — 21st-best among FBS defenses.
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