LSU vs Vanderbilt Prediction, Odds & Best Prop Bets โ€“ NCAAF, Week 8

Vanderbilt head coach Clark Lea argues a call in the first half of an NCAA college football game against Florida Saturday, Nov. 19, 2022, in Nashville, Tenn.
(AP Photo/Mark Humphrey)
  • Vanderbilt is a -2.5 point favorite vs. LSU
  • LSU vs. Vanderbilt Total (Over/Under): 48.5 points
  • TV Channel: ABC

LSU (5-1) visit FirstBank Stadium to take on Vanderbilt (5-1) on Oct. 18 in Nashville, TN. Kickoff is scheduled for 12:00pm EDT.

Vanderbilt is a betting favorite in Week 8, with the spread sitting at -2.5 (-115).

The LSU vs. Vanderbilt Over/Under is 48.5 total points.

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LSU vs. Vanderbilt Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
LSU+2.5 -10548.5 -110110
Vanderbilt -2.5 -11548.5 -110-135

LSU vs Vanderbilt Prediction:

The winning team model predicts Vanderbilt will win this game with 55.7% confidence, based on game simulations, offensive & defensive matchups and recent game results.

This winning team prediction factors in up-to-date player injuries for both LSU and Vanderbilt, key player performances this season and recent team trends.

LSU vs Vanderbilt Spread Prediction:

Based on recent against-the-spread trends, the model predicts Vanderbilt will cover the spread with 52.4% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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  • LSU has hit the 1H Game Total Under in 10 of their last 12 games (+7.85 Units / 58% ROI)
  • LSU has hit the Game Total Under in 9 of their last 12 games (+5.70 Units / 43% ROI)
  • LSU has hit the 1H Moneyline in 8 of their last 11 games (+5.20 Units / 6% ROI)
  • LSU has hit the Team Total Under in 5 of their last 6 games (+3.92 Units / 59% ROI)
  • LSU has hit the Moneyline in 7 of their last 11 games (+3.55 Units / 18% ROI)
  • Vanderbilt has hit the Moneyline in 7 of their last 12 games (+4.20 Units / 4% ROI)
  • Vanderbilt have covered the 1Q Spread in 9 of their last 13 games (+4.00 Units / 26% ROI)
  • Vanderbilt has hit the Team Total Over in 5 of their last 6 games (+3.85 Units / 55% ROI)
  • Vanderbilt have covered the Spread in 8 of their last 13 games (+2.50 Units / 18% ROI)
  • Vanderbilt has hit the 1Q Game Total Over in 8 of their last 13 games (+2.35 Units / 16% ROI)

LSU Against the Spread (ATS) Record

LSU is 3-2 against the spread this college football season (+0.85 Units / 15.6% ROI).

  • LSU is 3-1 when betting on the Moneyline for +2.75 Units / 37.67% ROI
  • LSU is 0-5 when betting the Over for -5.5 Units / -100% ROI
  • LSU is 5-0 when betting the Under for +5 Units / 90.91% ROI

Vanderbilt Against the Spread (ATS) Record

Vanderbilt iss 4-2 against the spread this college football season (+1.8 Units / 27.27% ROI).

  • Vanderbilt is 4-1 when betting on the Moneyline for +3.45 Units / 5.56% ROI
  • Vanderbilt is 3-3 when betting the Over for -0.3 Units / -4.55% ROI
  • Vanderbilt is 3-3 when betting the Under for -0.3 Units / -4.55% ROI

LSU: Keys to the Game vs. Vanderbilt

LSU was undefeated (6-0) when intercepting at least 1 pass last season– T-best in FBS; Average: .668

LSU was 9-2 (.818) when converting 55% or more of its red zone chances into touchdowns last season– T-22nd-best in FBS; Average: .624

LSU was 5-1 (.833) when having a turnover margin within one of the opposing team last season– 8th-best among Power Conference Teams; Average: .578

LSU was undefeated (6-0) when intercepting at least 1 pass last season– T-best among Power Conference Teams; Average: .688

Vanderbilt: Keys to the Game vs. LSU

LSU has 478 receptions in 19 games (25.2 per game) since the 2024 season — best among SEC skill players. Vanderbilt’s defense has allowed 20.9 receptions per game since the 2024 season — worst among SEC defenses.

LSU’s WRs has gained 1,041 yards on 95 receptions (just 11.0 YPR) this season — 2nd-worst among SEC WRs. Vanderbilt’s defense has allowed just 10.0 Yards Per Reception this season — 3rd-best among SEC defenses.

LSU’s WRs has gained 1,041 yards on 95 receptions (just 11.0 YPR) this season — 4th-worst among Power 5 WRs. Vanderbilt’s defense has allowed just 10.0 Yards Per Reception this season — 3rd-best among SEC defenses.

LSU’s TEs has 28 receptions in 6 games (4.7 per game) this season — 3rd-best among SEC TEs. Vanderbilt’s defense has allowed 4.3 receptions per game to TEs this season — T-20th-worst among FBS defenses.

LSU has averaged just 11.7 yards after the catch since the 2024 season — T-3rd-worst among SEC skill players. Vanderbilt’s defense has allowed just 10.9 RAC since the 2024 season — T-4th-best among SEC defenses.

Matchup Notes for LSU vs. Vanderbilt

LSU has 478 receptions in 19 games (25.2 per game) since the 2024 season — best among SEC skill players. Vanderbilt’s defense has allowed 20.9 receptions per game since the 2024 season — worst among SEC defenses.

LSU’s WRs has gained 1,041 yards on 95 receptions (just 11.0 YPR) this season — 2nd-worst among SEC WRs. Vanderbilt’s defense has allowed just 10.0 Yards Per Reception this season — 3rd-best among SEC defenses.

LSU’s WRs has gained 1,041 yards on 95 receptions (just 11.0 YPR) this season — 4th-worst among Power 5 WRs. Vanderbilt’s defense has allowed just 10.0 Yards Per Reception this season — 3rd-best among SEC defenses.

LSU’s TEs has 28 receptions in 6 games (4.7 per game) this season — 3rd-best among SEC TEs. Vanderbilt’s defense has allowed 4.3 receptions per game to TEs this season — T-20th-worst among FBS defenses.

LSU has averaged just 11.7 yards after the catch since the 2024 season — T-3rd-worst among SEC skill players. Vanderbilt’s defense has allowed just 10.9 RAC since the 2024 season — T-4th-best among SEC defenses.

LSU was undefeated (6-0) when intercepting at least 1 pass last season– T-best in FBS; Average: .668

LSU was 9-2 (.818) when converting 55% or more of its red zone chances into touchdowns last season– T-22nd-best in FBS; Average: .624

LSU was 5-1 (.833) when having a turnover margin within one of the opposing team last season– 8th-best among Power Conference Teams; Average: .578

LSU was undefeated (6-0) when intercepting at least 1 pass last season– T-best among Power Conference Teams; Average: .688

LSU Offensive Stats & Trends

LSU was undefeated (6-0) when intercepting at least 1 pass last season– T-best in FBS; Average: .668

LSU was 9-2 (.818) when converting 55% or more of its red zone chances into touchdowns last season– T-22nd-best in FBS; Average: .624

LSU was 5-1 (.833) when having a turnover margin within one of the opposing team last season– 8th-best among Power Conference Teams; Average: .578

LSU was undefeated (6-0) when intercepting at least 1 pass last season– T-best among Power Conference Teams; Average: .688

Vanderbilt Offensive Stats & Trends

LSU has 478 receptions in 19 games (25.2 per game) since the 2024 season — best among SEC skill players. Vanderbilt’s defense has allowed 20.9 receptions per game since the 2024 season — worst among SEC defenses.

LSU’s WRs has gained 1,041 yards on 95 receptions (just 11.0 YPR) this season — 2nd-worst among SEC WRs. Vanderbilt’s defense has allowed just 10.0 Yards Per Reception this season — 3rd-best among SEC defenses.

LSU’s WRs has gained 1,041 yards on 95 receptions (just 11.0 YPR) this season — 4th-worst among Power 5 WRs. Vanderbilt’s defense has allowed just 10.0 Yards Per Reception this season — 3rd-best among SEC defenses.

LSU’s TEs has 28 receptions in 6 games (4.7 per game) this season — 3rd-best among SEC TEs. Vanderbilt’s defense has allowed 4.3 receptions per game to TEs this season — T-20th-worst among FBS defenses.

LSU has averaged just 11.7 yards after the catch since the 2024 season — T-3rd-worst among SEC skill players. Vanderbilt’s defense has allowed just 10.9 RAC since the 2024 season — T-4th-best among SEC defenses.

LSU Defensive Stats & Trends

LSU was undefeated (6-0) when intercepting at least 1 pass last season– T-best in FBS; Average: .668

LSU was 9-2 (.818) when converting 55% or more of its red zone chances into touchdowns last season– T-22nd-best in FBS; Average: .624

LSU was 5-1 (.833) when having a turnover margin within one of the opposing team last season– 8th-best among Power Conference Teams; Average: .578

LSU was undefeated (6-0) when intercepting at least 1 pass last season– T-best among Power Conference Teams; Average: .688

Vanderbilt Defensive Stats & Trends

LSU has 478 receptions in 19 games (25.2 per game) since the 2024 season — best among SEC skill players. Vanderbilt’s defense has allowed 20.9 receptions per game since the 2024 season — worst among SEC defenses.

LSU’s WRs has gained 1,041 yards on 95 receptions (just 11.0 YPR) this season — 2nd-worst among SEC WRs. Vanderbilt’s defense has allowed just 10.0 Yards Per Reception this season — 3rd-best among SEC defenses.

LSU’s WRs has gained 1,041 yards on 95 receptions (just 11.0 YPR) this season — 4th-worst among Power 5 WRs. Vanderbilt’s defense has allowed just 10.0 Yards Per Reception this season — 3rd-best among SEC defenses.

LSU’s TEs has 28 receptions in 6 games (4.7 per game) this season — 3rd-best among SEC TEs. Vanderbilt’s defense has allowed 4.3 receptions per game to TEs this season — T-20th-worst among FBS defenses.

LSU has averaged just 11.7 yards after the catch since the 2024 season — T-3rd-worst among SEC skill players. Vanderbilt’s defense has allowed just 10.9 RAC since the 2024 season — T-4th-best among SEC defenses.


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