Notre Dame vs USC Prediction, Odds & Best Prop Bets – NCAAF, Week 14

Southern California head coach Lincoln Riley watches during the first half of an NCAA college football game against Utah, Saturday, Oct. 21, 2023, in Los Angeles. (AP Photo/Ryan Sun)
(AP Photo/Ryan Sun)
  • Notre Dame is a -7.5 point favorite vs. USC
  • Notre Dame vs. USC Total (Over/Under): 51.5 points
  • TV Channel: CBS

The Notre Dame Fighting Irish (10-1) visit United Airlines Field at the Los Angeles Memorial Coliseum to take on the USC Trojans (6-5) on Nov. 30 in Los Angeles, CA. Kickoff is scheduled for 3:30pm EST.

Notre Dame is a betting favorite in Week 14, with the spread sitting at -7.5 (-110).

The Notre Dame vs. USC Over/Under is 51.5 total points.

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Notre Dame vs. USC Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
Notre Dame-7.5 -11051.5 -110-275
USC +7.5 -11051.5 -110+230

Notre Dame vs USC Prediction:

The winning team model predicts Notre Dame will win this game with 70.3% confidence, based on game simulations, offensive & defensive matchups and recent game results.

This winning team prediction factors in up-to-date player injuries for both Notre Dame and USC, key player performances this season and recent team trends.

Notre Dame vs USC Spread Prediction:

Based on recent against-the-spread trends, the model predicts USC will cover the spread with 62.5% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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  • Notre Dame have covered the Spread in 10 of their last 12 games (+7.80 Units / 58% ROI)
  • Notre Dame have covered the 1H Spread in 9 of their last 12 games (+5.75 Units / 43% ROI)
  • Notre Dame has hit the 1Q Moneyline in 6 of their last 7 games (+3.40 Units / 14% ROI)
  • Notre Dame has hit the 1Q Game Total Over in 7 of their last 12 games (+1.65 Units / 12% ROI)
  • Notre Dame has hit the 1H Game Total Over in 7 of their last 12 games (+1.55 Units / 11% ROI)
  • USC have covered the Spread in their last 6 games at home (+6.00 Units / 90% ROI)
  • USC has hit the Moneyline in 5 of their last 6 games at home (+4.65 Units / 4% ROI)
  • USC has hit the 1H Moneyline in 5 of their last 6 games (+4.35 Units / 35% ROI)
  • USC has hit the 1H Game Total Over in 5 of their last 6 games at home (+3.90 Units / 56% ROI)
  • USC has hit the 1Q Game Total Over in 4 of their last 6 games at home (+2.80 Units / 39% ROI)

We’ve highlighted some favorite college football player prop bets for Notre Dame players, looking at profitable historical betting trends:

Best Notre Dame Player Prop Bets Today

  • Jaden Greathouse has hit the Receiving Yards Over in his last 2 games (+2.00 Units / 87% ROI)
  • Riley Leonard has hit the Rushing Yards Over in his last 2 games (+2.00 Units / 87% ROI)
  • Beaux Collins has hit the Receiving Yards Under in his last 2 games (+2.00 Units / 78% ROI)
  • Riley Leonard has hit the TD Passes Under in his last 2 games (+2.00 Units / 48% ROI)
  • Jeremiyah Love has hit the Rushing Yards Under in 3 of his last 4 games (+1.65 Units / 32% ROI)

Top NCAAF player prop bets for USC players, looking at profitable historical betting trends:

Best USC Player Prop Best Bets Today

  • Makai Lemon has hit the Receiving Yards Over in his last 3 games (+3.00 Units / 83% ROI)
  • Kyron Hudson has hit the Receiving Yards Over in his last 2 games (+2.00 Units / 83% ROI)
  • Ja’Kobi Lane has hit the Receiving Yards Under in his last 2 games at home (+2.00 Units / 83% ROI)
  • Zachariah Branch has hit the Receiving Yards Under in his last 2 games at home (+2.00 Units / 83% ROI)
  • Woody Marks has hit the Receiving Yards Under in his last game (+1.00 Units / 83% ROI)

Notre Dame Against the Spread (ATS) Record

Notre Dame is 9-2 against the spread this college football season (+6.8 Units / 55.51% ROI).

  • Notre Dame is 10-1 when betting on the Moneyline for -69.75 Units / -30.34% ROI
  • Notre Dame is 6-5 when betting the Over for +0.5 Units / 4.13% ROI
  • Notre Dame is 5-6 when betting the Under for -1.6 Units / -13.22% ROI

USC Against the Spread (ATS) Record

USC is 7-4 against the spread this college football season (+2.6 Units / 21.4% ROI).

  • USC is 6-5 when betting on the Moneyline for -3.25 Units / -2.55% ROI
  • USC is 5-6 when betting the Over for -1.6 Units / -13.22% ROI
  • USC is 6-5 when betting the Under for +0.5 Units / 4.13% ROI

Notre Dame: Keys to the Game vs. USC

Notre Dame is 15-3 (.833) when the opposing team rushes more than 30 times since the 2023 season– T-3rd-best in FBS; Average: .442

Notre Dame is 15-3 (.833) when the opposing team rushes more than 30 times since the 2023 season– T-3rd-best among Power Conference Teams; Average: .485

Notre Dame is 19-4 (.826) when allowing less than 5 yards per rush since the 2023 season– T-10th-best among Power Conference Teams; Average: .647

Notre Dame is 19-2 (.905) when making 3 or more explosive runs in a game since the 2023 season– 10th-best in FBS; Average: .640

USC: Keys to the Game vs. Notre Dame

USC is 5-8 (.357) when in a one score game since the 2023 season– 13th-worst among Power Conference Teams; Average: .525

USC is 12-4 (.750) when allowing less than 3 sacks since the 2023 season– T-31st-best in FBS; Average: .640

USC is 11-5 (.647) when having a turnover margin within one of the opposing team since the 2023 season– 34th-best in FBS; Average: .534

USC is 7-3 (.700) when not losing a fumble since the 2023 season– 35th-best in FBS; Average: .598

Matchup Notes for Notre Dame vs. USC

USC’s QBs has thrown for 3,101 passing yards in 11 games (281.9 YPG) this season — 14th-best among FBS teams. Notre Dame’s defense has allowed just 139.5 passing yards per game this season — best among FBS defenses.

USC’s TEs has gained 287 yards on 31 receptions (just 9.3 YPR) this season — 4th-worst among Big Ten TEs. Notre Dame’s defense has allowed just 11.0 Yards Per Reception this season — T-35th-best among FBS defenses.

USC’s offense has thrown for 20 or more yards on 12.0% of 902 attempts since the 2023 season — T-23rd-best among FBS offenses. Notre Dame’s defense allowed 20+ yards on just 6.5% of attempts since the 2023 season — 3rd-best among FBS defenses.

Notre Dame has gained 2,168 yards on 196 receptions (just 11.1 YPR) this season — T-24th-worst among FBS skill players. USC’s defense has allowed just 10.3 Yards Per Reception this season — T-12th-best among FBS defenses.

Notre Dame’s offense has thrown for 20 or more yards on 12.2% of 648 attempts since the 2023 season — T-19th-best among FBS offenses. USC’s defense allowed 20+ yards on 9.3% of attempts since the 2023 season — T-4th-worst among Big Ten defenses.

Notre Dame’s offense has thrown for 20 or more yards on just 8.3% of 301 attempts this season — T-22nd-worst among FBS offenses. USC’s defense allowed 20+ yards on just 7.3% of attempts this season — T-16th-best among FBS defenses.

Notre Dame Offensive Stats & Trends

Notre Dame RBs averaged 12.2 Yards per Carry (245 yards/20 carries) last week– best among FBS Teams; Average: 5.1

Notre Dame RBs averaged 12.0 yards from scrimmage per touch (251 yards / 21 touches) last week– best among FBS Teams; Average: 5.3

Notre Dame RBs rushed for 5 TDs last week– T-most among FBS Teams

Notre Dame RBs averaged 15.4 yards from scrimmage per touch (216 yards / 14 touches) on 1st down last week– best among FBS Teams; Average: 5.2

Notre Dame has gained 2,168 yards on 196 receptions (just 11.1 YPR) this season — T-24th-worst among FBS skill players. USC’s defense has allowed just 10.3 Yards Per Reception this season — T-12th-best among FBS defenses.

USC Offensive Stats & Trends

USC’s QBs has thrown for 3,101 passing yards in 11 games (281.9 YPG) this season — 14th-best among FBS teams. Notre Dame’s defense has allowed just 139.5 passing yards per game this season — best among FBS defenses.

USC’s TEs has gained 287 yards on 31 receptions (just 9.3 YPR) this season — 4th-worst among Big Ten TEs. Notre Dame’s defense has allowed just 11.0 Yards Per Reception this season — T-35th-best among FBS defenses.

USC TEs have averaged just 2.5 yards per reception (5 yards/2 catches) on 3rd and long since the 2023 season– worst among Power Conference Teams; Average: 12.1

USC’s offense has thrown for 20 or more yards on 12.0% of 902 attempts since the 2023 season — T-23rd-best among FBS offenses. Notre Dame’s defense allowed 20+ yards on just 6.5% of attempts since the 2023 season — 3rd-best among FBS defenses.

USC TEs have averaged just 2.5 yards per reception (5 yards/2 catches) on 3rd and long since the 2023 season– worst among Big Ten Teams; Average: 11.4

Notre Dame Fighting Irish Defensive Stats & Trends

Notre Dame opponents has averaged 47.1 Passing Attempts per TD (660 Pass Attempts/14 Passing TDs) since the 2023 season– 2nd-best in FBS; Average: 20.5

Notre Dame has allowed a Completion Pct of just 48% (69 completions/143 attempts) in the 1st half this season– best in FBS; Average: 62%

Notre Dame has allowed a Completion Pct of just 51% (334 completions/660 attempts) since the 2023 season– best in FBS; Average: 61%

Notre Dame has allowed a Completion Pct of just 48% (139 completions/289 attempts) this season– best in FBS; Average: 61%

Notre Dame has allowed just 149.2 receiving yards per game (3,580/24) since the 2023 season– 2nd-best in FBS; Average: 220.9

USC Trojans Defensive Stats & Trends

USC has allowed a Completion Pct of 87% (20 completions/23 attempts) on 3rd and short since the 2023 season– worst in the Big Ten; Average: 60%

USC has allowed a Completion Pct of 66% (518 completions/786 attempts) since the 2023 season– worst in the Big Ten; Average: 60%

USC has allowed a Completion Pct of 87% (20 completions/23 attempts) on 3rd and short since the 2023 season– worst among Power Conference Teams; Average: 61%

USC has allowed 10 touchdowns on 251 completions (25.1 Completions Per TD) this season– 3rd-best among Power Conference Teams; Average: 13.6

USC allowed 4.4 touchdowns per interception (31 TDs allowed, and 7 INT) in the 2023 season– worst in the Big Ten; Average: 1.6


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