Ohio vs E Michigan Prediction, Odds & Best Prop Bets – NCAAF, Week 9

BetMGM Betting Oct 24, 2025, 3:16 PM

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Eastern Michigan head coach Chris Creighton watches from the sideline during the first half of an NCAA college football game against Central Michigan, Friday, Nov. 25, 2022, in Ypsilanti, Mich. (AP Photo/Carlos Osorio)

(AP Photo/Carlos Osorio)

Ohio is a -12.5 point favorite vs. E Michigan
Ohio vs. Eastern Michigan Total (Over/Under): 60.5 points
TV Channel: CBSN

Ohio (4-3) visit Rynearson Stadium to take on Eastern Michigan (2-6) on Oct. 25 in Ypsilanti, MI. Kickoff is scheduled for 12:00pm EDT.

Ohio is a betting favorite in Week 9, with the spread sitting at -12.5 (-110).

The Ohio vs. Eastern Michigan Over/Under is 60.5 total points.

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Ohio vs. Eastern Michigan Odds, Spread, Over/Under:

	Spread	Total (O/U)	Moneyline
Ohio	-12.5 -110	60.5 -110	-500
Eastern Michigan	+12.5 -110	60.5 -110	375

Ohio vs Eastern Michigan Prediction:

The winning team model predicts Ohio will win this game with 76.2% confidence, based on game simulations, offensive & defensive matchups and recent game results.

This winning team prediction factors in up-to-date player injuries for both Ohio and E Michigan, key player performances this season and recent team trends.

Ohio vs Eastern Michigan Spread Prediction:

Based on recent against-the-spread trends, the model predicts Eastern Michigan will cover the spread with 51.1% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.

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Ohio Best Bets Today

Ohio has hit the 1H Moneyline in 11 of their last 14 games (+8.15 Units / 10% ROI)
Ohio have covered the Spread in 11 of their last 14 games (+7.70 Units / 50% ROI)
Ohio have covered the 1H Spread in 11 of their last 14 games (+7.45 Units / 46% ROI)
Ohio have covered the 1Q Spread in 11 of their last 14 games (+7.40 Units / 42% ROI)
Ohio has hit the Game Total Under in 6 of their last 7 away games (+4.90 Units / 64% ROI)

Eastern Michigan Best Bets Today

Eastern Michigan has hit the 1H Game Total Under in 4 of their last 5 games at home (+2.80 Units / 50% ROI)
Eastern Michigan has hit the 1Q Game Total Under in 4 of their last 5 games at home (+2.50 Units / 41% ROI)
Eastern Michigan has hit the Team Total Over in 4 of their last 6 games (+1.70 Units / 26% ROI)
Eastern Michigan have covered the Spread in 3 of their last 5 games at home (+0.80 Units / 15% ROI)
Eastern Michigan has hit the Game Total Over in 3 of their last 5 games at home (+0.80 Units / 15% ROI)

Ohio Against the Spread (ATS) Record

Ohio is 5-2 against the spread this college football season (+2.8 Units / 36.36% ROI).

Ohio is 4-3 when betting on the Moneyline for -3.3 Units / -5.92% ROI
Ohio is 4-3 when betting the Over for +0.7 Units / 9.09% ROI
Ohio is 3-4 when betting the Under for -1.4 Units / -18.18% ROI

Eastern Michigan Against the Spread (ATS) Record

E Michigan iss 4-4 against the spread this college football season (-0.4 Units / -4.55% ROI).

Eastern Michigan is 2-6 when betting on the Moneyline for -18.85 Units / -81.78% ROI
Eastern Michigan is 5-3 when betting the Over for +1.7 Units / 19.32% ROI
Eastern Michigan is 3-5 when betting the Under for -2.5 Units / -28.41% ROI

Ohio: Keys to the Game vs. Eastern Michigan

Ohio was 9-1 (.900) when allowing less than 3 sacks last season– T-2nd-best among Non-Power Conference Teams; Average: .583

Ohio was 11-1 (.917) when allowing less than 5 yards per rush last season– 3rd-best among Non-Power Conference Teams; Average: .612

Ohio was 10-1 (.909) when averaging more than 5 yards on first down plays last season– 4th-best among Non-Power Conference Teams; Average: .570

Ohio was 4-3 (.571) when sacking the QB less than 3 times last season– T-14th-best among Non-Power Conference Teams; Average: .388

Eastern Michigan: Keys to the Game vs. Ohio

Eastern Michigan WRs caught 4 touchdown passes last week– T-3rd-most among FBS Teams

Eastern Michigan Skill Players averaged 18.7 yards per reception (598 yards/32 catches) on 3rd and long last season– 4th-best among FBS Teams; Average: 12.9

Eastern Michigan WRs had 525 receiving yards in close and late situations last season– 2nd-most among FBS Teams

Eastern Michigan RBs have 6 receptions for 20 or more yards this season– T-4th-most among FBS Teams

Eastern Michigan Skill Players averaged 21.5 yards per reception (559 yards/26 catches) in close and late situations last season– T-best among FBS Teams; Average: 11.9

Matchup Notes for Ohio vs. Eastern Michigan