Purdue vs Northwestern Prediction, Odds & Best Prop Bets โ€“ NCAAF, Week 8

Northwestern running back Cam Porter (4) runs with the ball against Duke during the first half of an NCAA football game on Saturday, Sept. 10, 2022, in Evanston, Ill. (AP Photo/Kamil Krzaczynski)
(AP Photo/Kamil Krzaczynski)
  • Northwestern is a -3.5 point favorite vs. Purdue
  • Purdue vs. Northwestern Total (Over/Under): 46.5 points
  • TV Channel: BTN

Purdue (2-4) visit Northwestern Medicine Field at Martin Stadium to take on Northwestern (4-2) on Oct. 18 in Evanston, IL. Kickoff is scheduled for 3:00pm EDT.

Northwestern is a betting favorite in Week 8, with the spread sitting at -3.5 (-105).

The Purdue vs. Northwestern Over/Under is 46.5 total points.

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Purdue vs. Northwestern Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
Purdue+3.5 -11546.5 -105140
Northwestern -3.5 -10546.5 -115-165

Purdue vs Northwestern Prediction:

The winning team model predicts Northwestern will win this game with 67.4% confidence, based on game simulations, offensive & defensive matchups and recent game results.

This winning team prediction factors in up-to-date player injuries for both Purdue and Northwestern, key player performances this season and recent team trends.

Purdue vs Northwestern Spread Prediction:

Based on recent against-the-spread trends, the model predicts Purdue will cover the spread with 54.5% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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  • Purdue has hit the 1Q Game Total Under in 3 of their last 5 away games (+1.90 Units / 34% ROI)
  • Purdue has hit the Team Total Under in 4 of their last 6 games (+1.65 Units / 24% ROI)
  • Purdue has hit the Game Total Under in 7 of their last 12 games (+1.50 Units / 11% ROI)
  • Purdue have covered the 1Q Spread in 2 of their last 5 away games (+0.90 Units / 17% ROI)
  • Purdue has hit the 1H Game Total Over in 3 of their last 5 away games (+0.85 Units / 15% ROI)
  • Northwestern has hit the Moneyline in 5 of their last 11 games (+6.70 Units / 10% ROI)
  • Northwestern has hit the 1Q Moneyline in 5 of their last 10 games (+3.90 Units / 15% ROI)
  • Northwestern have covered the 1Q Spread in 8 of their last 12 games (+3.81 Units / 28% ROI)
  • Northwestern have covered the 1H Spread in 8 of their last 12 games (+3.35 Units / 24% ROI)
  • Northwestern has hit the Team Total Over in 4 of their last 5 games (+2.85 Units / 48% ROI)

Purdue Against the Spread (ATS) Record

Purdue is 3-3 against the spread this college football season (-0.4 Units / -5.97% ROI).

  • Purdue is 2-4 when betting on the Moneyline for -2 Units / -9.09% ROI
  • Purdue is 2-4 when betting the Over for -2.4 Units / -36.36% ROI
  • Purdue is 4-2 when betting the Under for +1.8 Units / 27.27% ROI

Northwestern Against the Spread (ATS) Record

Northwestern iss 4-2 against the spread this college football season (+1.8 Units / 27.27% ROI).

  • Northwestern is 4-2 when betting on the Moneyline for +9.5 Units / 15.91% ROI
  • Northwestern is 2-4 when betting the Over for -2.4 Units / -36.36% ROI
  • Northwestern is 4-2 when betting the Under for +1.8 Units / 27.27% ROI

Purdue: Keys to the Game vs. Northwestern

Purdue is winless (0-13) when allowing 120 or more rushing yards since the 2024 season– T-worst among Power Conference Teams; Average: .424

Purdue was winless (0-4) when in a one score game last season– T-worst among Power Conference Teams; Average: .514

Purdue was 1-6 (.143) when having a turnover margin within one of the opposing team last season– worst among Power Conference Teams; Average: .578

Purdue was winless (0-10) when the opposing team converts 55% or more of its red zone chances into touchdowns last season– T-worst in FBS; Average: .418

Northwestern: Keys to the Game vs. Purdue

Northwestern had no interceptions (0 pass attempts) in the Red Zone last season– T-worst in FBS; Average: 36.5

Northwestern allowed passes of 40+ yards on 1 of 20 attempts (5%) last week– worst in the Big Ten; Average: 1%

Northwestern did not allow an opponent to rush for 10 or more yards on any of their 14 carries on 3rd and long last season– T-best in the Big Ten; Average: 14%

Northwestern had no interceptions (0 pass attempts) in the Red Zone last season– T-worst in the Big Ten; Average: 38.1

Northwestern has forced one fumble on 185 carries this season– 2nd-worst among Power Conference Teams; Average: 47.9

Matchup Notes for Purdue vs. Northwestern

Northwestern had no interceptions (0 pass attempts) in the Red Zone last season– T-worst in FBS; Average: 36.5

Northwestern allowed passes of 40+ yards on 1 of 20 attempts (5%) last week– worst in the Big Ten; Average: 1%

Northwestern did not allow an opponent to rush for 10 or more yards on any of their 14 carries on 3rd and long last season– T-best in the Big Ten; Average: 14%

Northwestern had no interceptions (0 pass attempts) in the Red Zone last season– T-worst in the Big Ten; Average: 38.1

Northwestern has forced one fumble on 185 carries this season– 2nd-worst among Power Conference Teams; Average: 47.9

Purdue is winless (0-13) when allowing 120 or more rushing yards since the 2024 season– T-worst among Power Conference Teams; Average: .424

Purdue was winless (0-4) when in a one score game last season– T-worst among Power Conference Teams; Average: .514

Purdue was 1-6 (.143) when having a turnover margin within one of the opposing team last season– worst among Power Conference Teams; Average: .578

Purdue was winless (0-10) when the opposing team converts 55% or more of its red zone chances into touchdowns last season– T-worst in FBS; Average: .418

Purdue Offensive Stats & Trends

Purdue is winless (0-13) when allowing 120 or more rushing yards since the 2024 season– T-worst among Power Conference Teams; Average: .424

Purdue was winless (0-4) when in a one score game last season– T-worst among Power Conference Teams; Average: .514

Purdue was 1-6 (.143) when having a turnover margin within one of the opposing team last season– worst among Power Conference Teams; Average: .578

Purdue was winless (0-10) when the opposing team converts 55% or more of its red zone chances into touchdowns last season– T-worst in FBS; Average: .418

Northwestern Offensive Stats & Trends

Northwestern had no interceptions (0 pass attempts) in the Red Zone last season– T-worst in FBS; Average: 36.5

Northwestern allowed passes of 40+ yards on 1 of 20 attempts (5%) last week– worst in the Big Ten; Average: 1%

Northwestern did not allow an opponent to rush for 10 or more yards on any of their 14 carries on 3rd and long last season– T-best in the Big Ten; Average: 14%

Northwestern had no interceptions (0 pass attempts) in the Red Zone last season– T-worst in the Big Ten; Average: 38.1

Northwestern has forced one fumble on 185 carries this season– 2nd-worst among Power Conference Teams; Average: 47.9

Purdue Defensive Stats & Trends

Purdue is winless (0-13) when allowing 120 or more rushing yards since the 2024 season– T-worst among Power Conference Teams; Average: .424

Purdue was winless (0-4) when in a one score game last season– T-worst among Power Conference Teams; Average: .514

Purdue was 1-6 (.143) when having a turnover margin within one of the opposing team last season– worst among Power Conference Teams; Average: .578

Purdue was winless (0-10) when the opposing team converts 55% or more of its red zone chances into touchdowns last season– T-worst in FBS; Average: .418

Northwestern Defensive Stats & Trends

Northwestern had no interceptions (0 pass attempts) in the Red Zone last season– T-worst in FBS; Average: 36.5

Northwestern allowed passes of 40+ yards on 1 of 20 attempts (5%) last week– worst in the Big Ten; Average: 1%

Northwestern did not allow an opponent to rush for 10 or more yards on any of their 14 carries on 3rd and long last season– T-best in the Big Ten; Average: 14%

Northwestern had no interceptions (0 pass attempts) in the Red Zone last season– T-worst in the Big Ten; Average: 38.1

Northwestern has forced one fumble on 185 carries this season– 2nd-worst among Power Conference Teams; Average: 47.9


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