South Carolina vs Mississippi Prediction, Odds & Best Prop Bets โ€“ NCAAF, Week 10

Mississippi coach Lane Kiffin watches a play on the video board during the second half of the team's NCAA college football game against Central Arkansas in Oxford, Miss., Saturday, Sept. 10, 2022. (AP Photo/Rogelio V. Solis)
(AP Photo/Rogelio V. Solis)
  • Mississippi is a -12.5 point favorite vs. South Carolina
  • South Carolina vs. Ole Miss Total (Over/Under): 54.5 points
  • TV Channel: ESPN

South Carolina (3-5) visit Vaught-Hemingway Stadium to take on Ole Miss (7-1) on Nov. 1 in University, MS. Kickoff is scheduled for 7:00pm EDT.

Mississippi is a betting favorite in Week 10, with the spread sitting at -12.5 (-110).

The South Carolina vs. Ole Miss Over/Under is 54.5 total points.

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South Carolina vs. Ole Miss Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
South Carolina+12.5 -11054.5 -110375
Ole Miss -12.5 -11054.5 -110-500

South Carolina vs Ole Miss Prediction:

The winning team model predicts Ole Miss will win this game with 78.3% confidence, based on game simulations, offensive & defensive matchups and recent game results.

This winning team prediction factors in up-to-date player injuries for both South Carolina and Mississippi, key player performances this season and recent team trends.


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  • South Carolina has hit the 1H Game Total Under in 8 of their last 13 games (+3.45 Units / 23% ROI)
  • South Carolina has hit the Game Total Under in 4 of their last 5 away games (+2.90 Units / 53% ROI)
  • South Carolina have covered the 1H Spread in 4 of their last 5 away games (+2.85 Units / 50% ROI)
  • South Carolina has hit the 1Q Game Total Under in 3 of their last 5 away games (+1.90 Units / 34% ROI)
  • South Carolina has hit the Team Total Under in 5 of their last 8 games (+1.50 Units / 16% ROI)
  • Ole Miss has hit the 1H Moneyline in their last 12 games (+13.05 Units / 11% ROI)
  • Ole Miss has hit the Moneyline in their last 6 games at home (+6.10 Units / 12% ROI)
  • Ole Miss have covered the Spread in 6 of their last 8 games at home (+3.80 Units / 43% ROI)
  • Ole Miss has hit the 1H Game Total Under in 6 of their last 8 games at home (+3.70 Units / 40% ROI)
  • Ole Miss has hit the 1Q Game Total Under in 8 of their last 13 games (+2.25 Units / 15% ROI)

South Carolina Against the Spread (ATS) Record

South Carolina is 4-4 against the spread this college football season (-0.4 Units / -4.55% ROI).

  • South Carolina is 2-5 when betting on the Moneyline for -3.55 Units / -34.8% ROI
  • South Carolina is 3-5 when betting the Over for -2.5 Units / -28.41% ROI
  • South Carolina is 5-3 when betting the Under for +1.7 Units / 19.32% ROI

Ole Miss Against the Spread (ATS) Record

Mississippi iss 5-3 against the spread this college football season (+1.7 Units / 19.21% ROI).

  • Ole Miss is 5-1 when betting on the Moneyline for +4.65 Units / 37.2% ROI
  • Ole Miss is 5-3 when betting the Over for +1.7 Units / 19.32% ROI
  • Ole Miss is 3-5 when betting the Under for -2.5 Units / -28.41% ROI

South Carolina: Keys to the Game vs. Ole Miss

Ole Miss was 2-1 (.667) when sacking the QB less than 3 times last season– T-19th-best in FBS; Average: .429

Ole Miss is 6-2 (.750) when sacking the QB less than 3 times since the 2024 season– T-9th-best in FBS; Average: .436

Ole Miss was 9-2 (.818) when allowing less than 50% of third down conversion opportunities last season– T-15th-best among Power Conference Teams; Average: .645

Ole Miss was 10-2 (.833) when converting 55% or more of its red zone chances into touchdowns last season– 12th-best among Power Conference Teams; Average: .657

Ole Miss: Keys to the Game vs. South Carolina

South Carolina was 8-3 (.727) when allowing less than 50% of third down conversion opportunities last season– T-38th-best in FBS; Average: .602

South Carolina was 8-2 (.800) when making 7 or more explosive plays last season– T-27th-best in FBS; Average: .628

South Carolina was 6-4 (.600) when their opponent rushed more than 30 times last season– T-36th-best in FBS; Average: .442

South Carolina is 3-9 (.250) when the opposing team converts 55% or more of its red zone chances into touchdowns since the 2024 season– 13th-worst among Power Conference Teams; Average: .453

Matchup Notes for South Carolina vs. Ole Miss

South Carolina was 8-3 (.727) when allowing less than 50% of third down conversion opportunities last season– T-38th-best in FBS; Average: .602

South Carolina was 8-2 (.800) when making 7 or more explosive plays last season– T-27th-best in FBS; Average: .628

South Carolina was 6-4 (.600) when their opponent rushed more than 30 times last season– T-36th-best in FBS; Average: .442

South Carolina is 3-9 (.250) when the opposing team converts 55% or more of its red zone chances into touchdowns since the 2024 season– 13th-worst among Power Conference Teams; Average: .453

Ole Miss was 2-1 (.667) when sacking the QB less than 3 times last season– T-19th-best in FBS; Average: .429

Ole Miss is 6-2 (.750) when sacking the QB less than 3 times since the 2024 season– T-9th-best in FBS; Average: .436

Ole Miss was 9-2 (.818) when allowing less than 50% of third down conversion opportunities last season– T-15th-best among Power Conference Teams; Average: .645

Ole Miss was 10-2 (.833) when converting 55% or more of its red zone chances into touchdowns last season– 12th-best among Power Conference Teams; Average: .657

South Carolina Offensive Stats & Trends

Ole Miss was 2-1 (.667) when sacking the QB less than 3 times last season– T-19th-best in FBS; Average: .429

Ole Miss is 6-2 (.750) when sacking the QB less than 3 times since the 2024 season– T-9th-best in FBS; Average: .436

Ole Miss was 9-2 (.818) when allowing less than 50% of third down conversion opportunities last season– T-15th-best among Power Conference Teams; Average: .645

Ole Miss was 10-2 (.833) when converting 55% or more of its red zone chances into touchdowns last season– 12th-best among Power Conference Teams; Average: .657

Ole Miss Offensive Stats & Trends

South Carolina was 8-3 (.727) when allowing less than 50% of third down conversion opportunities last season– T-38th-best in FBS; Average: .602

South Carolina was 8-2 (.800) when making 7 or more explosive plays last season– T-27th-best in FBS; Average: .628

South Carolina was 6-4 (.600) when their opponent rushed more than 30 times last season– T-36th-best in FBS; Average: .442

South Carolina is 3-9 (.250) when the opposing team converts 55% or more of its red zone chances into touchdowns since the 2024 season– 13th-worst among Power Conference Teams; Average: .453

South Carolina Defensive Stats & Trends

Ole Miss was 2-1 (.667) when sacking the QB less than 3 times last season– T-19th-best in FBS; Average: .429

Ole Miss is 6-2 (.750) when sacking the QB less than 3 times since the 2024 season– T-9th-best in FBS; Average: .436

Ole Miss was 9-2 (.818) when allowing less than 50% of third down conversion opportunities last season– T-15th-best among Power Conference Teams; Average: .645

Ole Miss was 10-2 (.833) when converting 55% or more of its red zone chances into touchdowns last season– 12th-best among Power Conference Teams; Average: .657

Ole Miss Defensive Stats & Trends

South Carolina was 8-3 (.727) when allowing less than 50% of third down conversion opportunities last season– T-38th-best in FBS; Average: .602

South Carolina was 8-2 (.800) when making 7 or more explosive plays last season– T-27th-best in FBS; Average: .628

South Carolina was 6-4 (.600) when their opponent rushed more than 30 times last season– T-36th-best in FBS; Average: .442

South Carolina is 3-9 (.250) when the opposing team converts 55% or more of its red zone chances into touchdowns since the 2024 season– 13th-worst among Power Conference Teams; Average: .453


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