Syracuse vs Purdue Prediction, Odds & Best Prop Bets – NCAAF, Week 3

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Purdue defensive end Kydran Jenkins (44) reacts during the second half of an NCAA college football game against Indiana, Saturday, Nov. 26, 2022, in Bloomington, Ind. (AP Photo/Darron Cummings)
(AP Photo/Darron Cummings)
BetMGM Betting @BETMGM Sep 16, 2023, 11:15 AM
  • Syracuse is a -2.5 point favorite vs. Purdue
  • Total (Over/Under): 57.5 points
  • Watch the game on NBC/Peacock

The Syracuse Orange visit Ross-Ade Stadium to take on the Purdue Boilermakers on Sep. 16. Kickoff is scheduled for 7:30pm EDT in West Lafayette.

Syracuse is a betting favorite in Week 3, with the spread sitting at -2.5 (-110).

The Syracuse vs. Purdue Over/Under is 56.5 total points.

Bet now on Purdue vs Syracuse & all NCAAF games with BetMGM

Syracuse vs. Purdue Odds, Spread, Over/Under for Week 3

SpreadTotal (O/U)Moneyline
Syracuse-2.5 -11056.5 -110-135
Purdue +2.5 -11056.5 -110+110

Syracuse vs Purdue Prediction for Week 3

Based on recent trends, the winning team model predicts Syracuse will win this game with 54.3% confidence.

Syracuse vs Purdue Spread Prediction for Week 3

Based on recent against-the-spread trends, the model predicts Purdue will cover the spread with 76.3% confidence.

Both predictions factor in up-to-date player injuries for both Syracuse and Purdue, plus offensive & defensive matchups, recent games and key player performances this season.


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  • Syracuse has hit the 1Q Game Total Under in 3 of their last 4 away games (+3.00 Units / 48% ROI)
  • Syracuse have covered the 1Q Spread in 6 of their last 9 games (+2.90 Units / 26% ROI)
  • Syracuse has hit the Game Total Over in 3 of their last 4 away games (+1.90 Units / 43% ROI)
  • Syracuse has hit the 1H Game Total Under in 3 of their last 4 away games (+1.90 Units / 42% ROI)
  • Syracuse has hit the 1Q Moneyline in 4 of their last 9 games (+1.67 Units / 14% ROI)
  • Purdue has hit the 1Q Game Total Under in 9 of their last 12 games (+5.50 Units / 39% ROI)
  • Purdue has hit the Moneyline in 8 of their last 14 games (+3.75 Units / 10% ROI)
  • Purdue has hit the Team Total Under in 4 of their last 5 games (+2.85 Units / 50% ROI)
  • Purdue has hit the 1Q Moneyline in 3 of their last 5 games at home (+2.00 Units / 17% ROI)
  • Purdue has hit the 1H Game Total Over in 3 of their last 4 games at home (+1.90 Units / 43% ROI)

Best Syracuse Player Prop Bets Today

We’ve highlighted some favorite college football player prop bets for Syracuse players for Week 3, looking at profitable historical betting trends:

  • Oronde Gadsden II has hit the Receiving Yards Over in his last 6 games (+6.00 Units / 83% ROI)
  • Garrett Shrader has hit the TD Passes Under in 4 of his last 5 games (+2.95 Units / 40% ROI)
  • Garrett Shrader has hit the Rushing Yards Over in 4 of his last 6 games (+1.85 Units / 27% ROI)
  • Garrett Shrader has hit the Passing Yards Under in 4 of his last 6 games (+1.60 Units / 22% ROI)

Best Purdue Player Prop Best Bets Today

Top NCAAF player prop bets for Purdue players for Week 3, looking at profitable historical betting trends:

  • TJ Sheffield has hit the Receiving Yards Under in 3 of his last 5 games (+0.60 Units / 10% ROI)

Syracuse Against the Spread (ATS) Record

Syracuse is 2-0 against the spread this college football season (+2 Units / 90.91% ROI).

  • Syracuse is 1-0 when betting on the Moneyline for +1 Units / 4.8% ROI
  • Syracuse is 1-1 when betting the Over for -0.1 Units / -4.55% ROI
  • Syracuse is 1-1 when betting the Under for -0.1 Units / -4.55% ROI

Purdue Against the Spread (ATS) Record

Purdue is 1-1 against the spread this college football season (-0.1 Units / -4.44% ROI).

  • Purdue is 1-1 when betting on the Moneyline for -0.7 Units / -25.45% ROI
  • Purdue is 1-1 when betting the Over for -0.1 Units / -4.55% ROI
  • Purdue is 1-1 when betting the Under for -0.1 Units / -4.55% ROI

Syracuse: Keys to the Game vs. Purdue

Syracuse is 4-11 (.267) when having a turnover margin within one of the opposing team since the 2021 season– tied for 15th-worst among Power 5 Teams; Average: .497

Syracuse is 3-9 (.250) when allowing 100 or more rushing yards since the 2021 season– tied for 14th-worst among Power 5 Teams; Average: .398

Syracuse is 2-8 (.200) when in a one score game since the 2021 season– tied for 4th-worst among Power 5 Teams; Average: .494

Purdue: Keys to the Game vs. Syracuse

Purdue is winless (0-3) when intercepting no passes since the 2022 season– tied for worst in FBS; Average: .347

Purdue is 12-3 (.800) when intercepting at least 1 pass since the 2021 season– tied for 13th-best among Power 5 Teams; Average: .625

Purdue is undefeated (5-0) when rushing for 120 or more yards since the 2022 season– tied for 8th-best in FBS; Average: .559

Purdue is 12-4 (.750) when allowing less than 5 yards per rush since the 2021 season– tied for 13th-best among Power 5 Teams; Average: .603

Matchup Notes for Syracuse vs. Purdue

Purdue’s WRs has gained 2,993 yards on 258 receptions (just 11.6 YPR) since the 2022 season — tied for 16th-worst among FBS WRs. Syracuse’s defense has allowed just 9.4 Yards Per Reception since the 2022 season — second-best among P5 defenses.

Purdue’s WRs has gained 356 yards on 20 receptions (17.8 YPR) this season — fifth-best among Power 5 WRs. Syracuse’s defense has allowed just 7.0 Yards Per Reception this season — fourth-best among FBS defenses.

Purdue’s WRs has gained 2,993 yards on 258 receptions (just 11.6 YPR) since the 2022 season — tied for 16th-worst among FBS WRs. Syracuse’s defense has allowed just 9.4 Yards Per Reception since the 2022 season — second-best among FBS defenses.

Syracuse has gained 3,738 yards on 279 receptions (13.4 YPR) since the 2022 season — tied for 17th-best among FBS skill players. Purdue’s defense has allowed 13.2 Yards Per Reception since the 2022 season — fourth-worst among P5 defenses.

Syracuse has gained 3,738 yards on 279 receptions (13.4 YPR) since the 2022 season — tied for 17th-best among FBS skill players. Purdue’s defense has allowed 13.2 Yards Per Reception since the 2022 season — worst among Big Ten defenses.

Syracuse’s WRs has gained 622 yards on 36 receptions (17.3 YPR) this season — best among ACC WRs. Purdue’s defense has allowed 12.9 Yards Per Reception this season — tied for 28th-worst among FBS defenses.

Syracuse Offensive Stats & Trends

Syracuse WRs have caught 4 touchdown passes in the Red Zone this season– tied for most among FBS Teams

Syracuse Skill Players have caught 7 touchdown passes this season– 3rd-most among FBS Teams

Syracuse Skill Players have caught 5 touchdown passes in the Red Zone this season– tied for most among FBS Teams

Syracuse has gained 3,738 yards on 279 receptions (13.4 YPR) since the 2022 season — tied for 17th-best among FBS skill players. Purdue’s defense has allowed 13.2 Yards Per Reception since the 2022 season — fourth-worst among P5 defenses.

Syracuse TEs have been targeted 7 times in the 1st quarter this season– most among FBS Teams

Purdue Offensive Stats & Trends

Purdue’s WRs has gained 2,993 yards on 258 receptions (just 11.6 YPR) since the 2022 season — tied for 16th-worst among FBS WRs. Syracuse’s defense has allowed just 9.4 Yards Per Reception since the 2022 season — second-best among P5 defenses.

Purdue’s WRs has gained 356 yards on 20 receptions (17.8 YPR) this season — fifth-best among Power 5 WRs. Syracuse’s defense has allowed just 7.0 Yards Per Reception this season — fourth-best among FBS defenses.

Purdue’s WRs has gained 2,993 yards on 258 receptions (just 11.6 YPR) since the 2022 season — tied for 16th-worst among FBS WRs. Syracuse’s defense has allowed just 9.4 Yards Per Reception since the 2022 season — second-best among FBS defenses.

Purdue Skill Players have averaged 28.0 receptions per game (811/29) since the 2021 season– 3rd best among FBS Teams; Average: 19.1

Purdue has gained 502 yards on 40 receptions (12.6 YPR) this season — fourth-best among Big Ten skill players. Syracuse’s defense has allowed just 7.0 Yards Per Reception this season — fourth-best among FBS defenses.

Syracuse Orange Defensive Stats & Trends

Syracuse has allowed a passer rating of just 95.9 (122.0 Pass Attempts) since the 2021 season– best among Power 5 Teams; Average: 129.5

Syracuse has allowed passes of 20+ yards on just 4 of 122 attempts (3%) since the 2021 season– worst among Power 5 Teams; Average: 10%

Syracuse has allowed a passer rating of just 95.9 (122.0 Pass Attempts) since last season– best among Power 5 Teams; Average: 128.2

Syracuse has allowed 4.7 yards from scrimmage per touch (926 yards / 195 touches) since the 2021 season– best among Power 5 Teams; Average: 6.7

Syracuse has allowed 3.5 yards from scrimmage per touch (295 yards / 84 touches) on 1st down since the 2021 season– best among Power 5 Teams; Average: 6.8

Purdue Boilermakers Defensive Stats & Trends

Purdue has allowed 4 TD passes this season– tied for most among Power 5 Teams

Purdue allowed first downs on 10% of pass attempts on 3rd and long in the 2022 season– best among Power 5 Teams; Average: 27%

Purdue has allowed 34 TD passes since last season– tied for most among Power 5 Teams

Purdue has allowed 8 TD passes in close and late situations since last season– tied for 3rd most in FBS

Purdue has allowed 19 TD passes in the Red Zone since last season– tied for 2nd most among Power 5 Teams


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.