USC vs Nebraska Prediction, Odds & Best Prop Bets โ€“ NCAAF, Week 10

Nebraska head coach Matt Rhule reacts during the first half of an NCAA college football game against Minnesota, Thursday, Aug. 31, 2023, in Minneapolis. (AP Photo/Abbie Parr)
(AP Photo/Abbie Parr)
  • USC is a -6.5 point favorite vs. Nebraska
  • USC vs. Nebraska Total (Over/Under): 59.5 points
  • TV Channel: NBC | PEAC

USC (5-2) visit Memorial Stadium (Lincoln, NE) to take on Nebraska (6-2) on Nov. 1 in Lincoln, NE. Kickoff is scheduled for 7:30pm EDT.

USC is a betting favorite in Week 10, with the spread sitting at -6.5 (-110).

The USC vs. Nebraska Over/Under is 59.5 total points.

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USC vs. Nebraska Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
USC-6.5 -11059.5 -115-250
Nebraska +6.5 -11059.5 -105200

USC vs Nebraska Prediction:

The winning team model predicts USC will win this game with 66.5% confidence, based on game simulations, offensive & defensive matchups and recent game results.

This winning team prediction factors in up-to-date player injuries for both USC and Nebraska, key player performances this season and recent team trends.

USC vs Nebraska Spread Prediction:

Based on recent against-the-spread trends, the model predicts USC will cover the spread with 51.9% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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  • USC has hit the 1H Game Total Under in their last 6 away games (+6.00 Units / 90% ROI)
  • USC have covered the 1H Spread in 9 of their last 12 games (+5.40 Units / 38% ROI)
  • USC has hit the 1Q Moneyline in 6 of their last 10 games (+3.25 Units / 8% ROI)
  • USC has hit the Moneyline in 7 of their last 11 games (+1.90 Units / 2% ROI)
  • USC has hit the 1H Moneyline in 6 of their last 9 games (+1.85 Units / 2% ROI)
  • Nebraska has hit the Team Total Over in their last 5 games at home (+5.00 Units / 86% ROI)
  • Nebraska has hit the Game Total Over in 6 of their last 7 games at home (+4.90 Units / 64% ROI)
  • Nebraska has hit the 1H Moneyline in 8 of their last 11 games (+3.65 Units / 7% ROI)
  • Nebraska have covered the 1H Spread in 8 of their last 12 games (+3.45 Units / 25% ROI)
  • Nebraska has hit the 1Q Moneyline in 6 of their last 9 games (+1.30 Units / 4% ROI)

USC Against the Spread (ATS) Record

USC is 4-3 against the spread this college football season (+0.7 Units / 9.09% ROI).

  • USC is 4-2 when betting on the Moneyline for +0.65 Units / 0.85% ROI
  • USC is 4-3 when betting the Over for +0.7 Units / 9.09% ROI
  • USC is 3-4 when betting the Under for -1.4 Units / -18.18% ROI

Nebraska Against the Spread (ATS) Record

Nebraska iss 1-5 against the spread this college football season (-4.55 Units / -58.71% ROI).

  • Nebraska is 4-2 when betting on the Moneyline for +0.45 Units / 2.88% ROI
  • Nebraska is 5-2 when betting the Over for +2.8 Units / 36.36% ROI
  • Nebraska is 2-5 when betting the Under for -3.5 Units / -45.45% ROI

USC: Keys to the Game vs. Nebraska

Nebraska has allowed one passing TD (11 pass attempts) in the Red Zone this season– 3rd-best in FBS; Average: 3.8

Nebraska opponents has averaged 68.3 Passing Attempts per TD (205 Pass Attempts/3 Passing TDs) this season– 2nd-best among Power Conference Teams; Average: 23.2

Nebraska opponents has averaged 68.3 Passing Attempts per TD (205 Pass Attempts/3 Passing TDs) this season– 2nd-best in FBS; Average: 21.5

Nebraska has allowed one passing TD (11 pass attempts) in the Red Zone this season– 2nd-best among Power Conference Teams; Average: 4.0

Nebraska did not tackle opponents for a loss on any of 30 rushing attempts last week– worst in the Big Ten; Average: 12%.

Nebraska: Keys to the Game vs. USC

Nebraska’s WRs has gained 1,461 yards on 103 receptions (14.2 YPR) this season — 5th-best among Big Ten WRs. USC’s defense has allowed just 6.8 Yards Per Reception to TEs this season — 4th-best among FBS defenses.

Nebraska TEs had no touchdowns on 5 receptions in the Red Zone last season– T-worst Receptions Per TD among Power Conference Teams; Average: 2.0

Nebraska has 472 receptions in 21 games (22.5 per game) since the 2024 season — 3rd-best among Big Ten skill players. USC’s defense has allowed 21.4 receptions per game since the 2024 season — worst among Big Ten defenses.

Nebraska Skill Players averaged a touchdown every 3.8 receptions (34 Rec/9 TDs) in the Red Zone last season– worst Receptions Per TD among Big Ten Teams; Average: 2.1

Nebraska has averaged just 10.4 yards after the catch since the 2024 season — T-3rd-worst among Power 5 skill players. USC’s defense has allowed just 10.8 RAC since the 2024 season — T-24th-best among FBS defenses.

Matchup Notes for USC vs. Nebraska

Nebraska’s WRs has gained 1,461 yards on 103 receptions (14.2 YPR) this season — 5th-best among Big Ten WRs. USC’s defense has allowed just 6.8 Yards Per Reception to TEs this season — 4th-best among FBS defenses.

Nebraska TEs had no touchdowns on 5 receptions in the Red Zone last season– T-worst Receptions Per TD among Power Conference Teams; Average: 2.0

Nebraska has 472 receptions in 21 games (22.5 per game) since the 2024 season — 3rd-best among Big Ten skill players. USC’s defense has allowed 21.4 receptions per game since the 2024 season — worst among Big Ten defenses.

Nebraska Skill Players averaged a touchdown every 3.8 receptions (34 Rec/9 TDs) in the Red Zone last season– worst Receptions Per TD among Big Ten Teams; Average: 2.1

Nebraska has averaged just 10.4 yards after the catch since the 2024 season — T-3rd-worst among Power 5 skill players. USC’s defense has allowed just 10.8 RAC since the 2024 season — T-24th-best among FBS defenses.

Nebraska has allowed one passing TD (11 pass attempts) in the Red Zone this season– 3rd-best in FBS; Average: 3.8

Nebraska opponents has averaged 68.3 Passing Attempts per TD (205 Pass Attempts/3 Passing TDs) this season– 2nd-best among Power Conference Teams; Average: 23.2

Nebraska opponents has averaged 68.3 Passing Attempts per TD (205 Pass Attempts/3 Passing TDs) this season– 2nd-best in FBS; Average: 21.5

Nebraska has allowed one passing TD (11 pass attempts) in the Red Zone this season– 2nd-best among Power Conference Teams; Average: 4.0

Nebraska did not tackle opponents for a loss on any of 30 rushing attempts last week– worst in the Big Ten; Average: 12%.

USC Offensive Stats & Trends

Nebraska has allowed one passing TD (11 pass attempts) in the Red Zone this season– 3rd-best in FBS; Average: 3.8

Nebraska opponents has averaged 68.3 Passing Attempts per TD (205 Pass Attempts/3 Passing TDs) this season– 2nd-best among Power Conference Teams; Average: 23.2

Nebraska opponents has averaged 68.3 Passing Attempts per TD (205 Pass Attempts/3 Passing TDs) this season– 2nd-best in FBS; Average: 21.5

Nebraska has allowed one passing TD (11 pass attempts) in the Red Zone this season– 2nd-best among Power Conference Teams; Average: 4.0

Nebraska did not tackle opponents for a loss on any of 30 rushing attempts last week– worst in the Big Ten; Average: 12%.

Nebraska Offensive Stats & Trends

Nebraska’s WRs has gained 1,461 yards on 103 receptions (14.2 YPR) this season — 5th-best among Big Ten WRs. USC’s defense has allowed just 6.8 Yards Per Reception to TEs this season — 4th-best among FBS defenses.

Nebraska TEs had no touchdowns on 5 receptions in the Red Zone last season– T-worst Receptions Per TD among Power Conference Teams; Average: 2.0

Nebraska has 472 receptions in 21 games (22.5 per game) since the 2024 season — 3rd-best among Big Ten skill players. USC’s defense has allowed 21.4 receptions per game since the 2024 season — worst among Big Ten defenses.

Nebraska Skill Players averaged a touchdown every 3.8 receptions (34 Rec/9 TDs) in the Red Zone last season– worst Receptions Per TD among Big Ten Teams; Average: 2.1

Nebraska has averaged just 10.4 yards after the catch since the 2024 season — T-3rd-worst among Power 5 skill players. USC’s defense has allowed just 10.8 RAC since the 2024 season — T-24th-best among FBS defenses.

USC Defensive Stats & Trends

Nebraska has allowed one passing TD (11 pass attempts) in the Red Zone this season– 3rd-best in FBS; Average: 3.8

Nebraska opponents has averaged 68.3 Passing Attempts per TD (205 Pass Attempts/3 Passing TDs) this season– 2nd-best among Power Conference Teams; Average: 23.2

Nebraska opponents has averaged 68.3 Passing Attempts per TD (205 Pass Attempts/3 Passing TDs) this season– 2nd-best in FBS; Average: 21.5

Nebraska has allowed one passing TD (11 pass attempts) in the Red Zone this season– 2nd-best among Power Conference Teams; Average: 4.0

Nebraska did not tackle opponents for a loss on any of 30 rushing attempts last week– worst in the Big Ten; Average: 12%.

Nebraska Defensive Stats & Trends

Nebraska’s WRs has gained 1,461 yards on 103 receptions (14.2 YPR) this season — 5th-best among Big Ten WRs. USC’s defense has allowed just 6.8 Yards Per Reception to TEs this season — 4th-best among FBS defenses.

Nebraska TEs had no touchdowns on 5 receptions in the Red Zone last season– T-worst Receptions Per TD among Power Conference Teams; Average: 2.0

Nebraska has 472 receptions in 21 games (22.5 per game) since the 2024 season — 3rd-best among Big Ten skill players. USC’s defense has allowed 21.4 receptions per game since the 2024 season — worst among Big Ten defenses.

Nebraska Skill Players averaged a touchdown every 3.8 receptions (34 Rec/9 TDs) in the Red Zone last season– worst Receptions Per TD among Big Ten Teams; Average: 2.1

Nebraska has averaged just 10.4 yards after the catch since the 2024 season — T-3rd-worst among Power 5 skill players. USC’s defense has allowed just 10.8 RAC since the 2024 season — T-24th-best among FBS defenses.


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