USC vs Notre Dame Prediction, Odds & Best Prop Bets โ€“ NCAAF, Week 8

Notre Dame head coach Marcus Freeman looks at the scoreboard during the first half of the team's NCAA college football game against Stanford in South Bend, Ind., Saturday, Oct. 15, 2022.
(AP Photo/Nam Y. Huh)
  • Notre Dame is a -9.5 point favorite vs. USC
  • USC vs. Notre Dame Total (Over/Under): 61.5 points
  • TV Channel: NBC | PEAC

USC (5-1) visit Notre Dame Stadium to take on Notre Dame (4-2) on Oct. 18 in South Bend, IN. Kickoff is scheduled for 7:30pm EDT.

Notre Dame is a betting favorite in Week 8, with the spread sitting at -9.5 (-105).

The USC vs. Notre Dame Over/Under is 61.5 total points.

Bet now on Notre Dame vs USC & all NCAAF games with BetMGM

USC vs. Notre Dame Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
USC+9.5 -11561.5 -110275
Notre Dame -9.5 -10561.5 -110-350

USC vs Notre Dame Prediction:

The winning team model predicts Notre Dame will win this game with 74.2% confidence, based on game simulations, offensive & defensive matchups and recent game results.

This winning team prediction factors in up-to-date player injuries for both USC and Notre Dame, key player performances this season and recent team trends.


Bet now on Notre Dame vs USC and all games with BetMGM


  • USC have covered the 1H Spread in 10 of their last 13 games (+6.40 Units / 42% ROI)
  • USC has hit the 1H Game Total Under in 5 of their last 6 away games (+5.00 Units / 75% ROI)
  • USC has hit the 1H Moneyline in 8 of their last 10 games (+4.85 Units / 5% ROI)
  • USC has hit the 1Q Game Total Under in 5 of their last 6 away games (+3.95 Units / 56% ROI)
  • USC has hit the 1Q Moneyline in 7 of their last 11 games (+3.65 Units / 8% ROI)
  • Notre Dame has hit the Moneyline in 13 of their last 15 games (+9.15 Units / 6% ROI)
  • Notre Dame have covered the Spread in 12 of their last 15 games (+8.70 Units / 52% ROI)
  • Notre Dame has hit the 1Q Moneyline in 11 of their last 13 games (+8.40 Units / 19% ROI)
  • Notre Dame has hit the 1H Moneyline in 11 of their last 14 games (+6.35 Units / 7% ROI)
  • Notre Dame have covered the 1Q Spread in 8 of their last 15 games (+3.35 Units / 19% ROI)

USC Against the Spread (ATS) Record

USC is 3-3 against the spread this college football season (-0.3 Units / -4.55% ROI).

  • USC is 4-1 when betting on the Moneyline for +1.65 Units / 2.19% ROI
  • USC is 4-2 when betting the Over for +1.8 Units / 27.27% ROI
  • USC is 2-4 when betting the Under for -2.4 Units / -36.36% ROI

Notre Dame Against the Spread (ATS) Record

Notre Dame iss 3-3 against the spread this college football season (-0.3 Units / -4.51% ROI).

  • Notre Dame is 4-2 when betting on the Moneyline for +0.15 Units / 0.23% ROI
  • Notre Dame is 4-2 when betting the Over for +1.8 Units / 27.27% ROI
  • Notre Dame is 2-4 when betting the Under for -2.4 Units / -36.36% ROI

USC: Keys to the Game vs. Notre Dame

USC allowed 4.4 touchdowns per interception (31 TDs allowed, and 7 INT) in the 2023 season– 3rd-worst among Power Conference Teams; Average: 1.7

USC allowed 12 TDs in close and late situations in the 2023 season– most in the Big Ten

USC has not allowed an opponent to rush for 10 or more yards on any of their 23 carries on 3rd and long since the 2024 season– best in the Big Ten; Average: 15%

USC had no interceptions and 16 TD passes allowed in the Red Zone in the 2023 season– T-worst in the Big Ten; Average: 12.5

USC allowed 4.4 touchdowns per interception (31 TDs allowed, and 7 INT) in the 2023 season– worst in the Big Ten; Average: 1.6

Notre Dame: Keys to the Game vs. USC

USC is 9-1 (.900) when rushing more than 30 times since the 2024 season– 9th-best among Power Conference Teams; Average: .678

USC is 10-4 (.714) when having a turnover margin within one of the opposing team since the 2024 season– T-27th-best in FBS; Average: .541

USC was 2-5 (.250) when not forcing a fumble in the 2023 season– T-11th-worst among Power Conference Teams; Average: .513

USC is 7-3 (.700) when committing less than 60 yards in penalties since the 2024 season– T-28th-best in FBS; Average: .528

Matchup Notes for USC vs. Notre Dame

USC is 9-1 (.900) when rushing more than 30 times since the 2024 season– 9th-best among Power Conference Teams; Average: .678

USC is 10-4 (.714) when having a turnover margin within one of the opposing team since the 2024 season– T-27th-best in FBS; Average: .541

USC was 2-5 (.250) when not forcing a fumble in the 2023 season– T-11th-worst among Power Conference Teams; Average: .513

USC is 7-3 (.700) when committing less than 60 yards in penalties since the 2024 season– T-28th-best in FBS; Average: .528

USC allowed 4.4 touchdowns per interception (31 TDs allowed, and 7 INT) in the 2023 season– 3rd-worst among Power Conference Teams; Average: 1.7

USC allowed 12 TDs in close and late situations in the 2023 season– most in the Big Ten

USC has not allowed an opponent to rush for 10 or more yards on any of their 23 carries on 3rd and long since the 2024 season– best in the Big Ten; Average: 15%

USC had no interceptions and 16 TD passes allowed in the Red Zone in the 2023 season– T-worst in the Big Ten; Average: 12.5

USC allowed 4.4 touchdowns per interception (31 TDs allowed, and 7 INT) in the 2023 season– worst in the Big Ten; Average: 1.6

USC Offensive Stats & Trends

USC allowed 4.4 touchdowns per interception (31 TDs allowed, and 7 INT) in the 2023 season– 3rd-worst among Power Conference Teams; Average: 1.7

USC allowed 12 TDs in close and late situations in the 2023 season– most in the Big Ten

USC has not allowed an opponent to rush for 10 or more yards on any of their 23 carries on 3rd and long since the 2024 season– best in the Big Ten; Average: 15%

USC had no interceptions and 16 TD passes allowed in the Red Zone in the 2023 season– T-worst in the Big Ten; Average: 12.5

USC allowed 4.4 touchdowns per interception (31 TDs allowed, and 7 INT) in the 2023 season– worst in the Big Ten; Average: 1.6

Notre Dame Offensive Stats & Trends

USC is 9-1 (.900) when rushing more than 30 times since the 2024 season– 9th-best among Power Conference Teams; Average: .678

USC is 10-4 (.714) when having a turnover margin within one of the opposing team since the 2024 season– T-27th-best in FBS; Average: .541

USC was 2-5 (.250) when not forcing a fumble in the 2023 season– T-11th-worst among Power Conference Teams; Average: .513

USC is 7-3 (.700) when committing less than 60 yards in penalties since the 2024 season– T-28th-best in FBS; Average: .528

USC Defensive Stats & Trends

USC allowed 4.4 touchdowns per interception (31 TDs allowed, and 7 INT) in the 2023 season– 3rd-worst among Power Conference Teams; Average: 1.7

USC allowed 12 TDs in close and late situations in the 2023 season– most in the Big Ten

USC has not allowed an opponent to rush for 10 or more yards on any of their 23 carries on 3rd and long since the 2024 season– best in the Big Ten; Average: 15%

USC had no interceptions and 16 TD passes allowed in the Red Zone in the 2023 season– T-worst in the Big Ten; Average: 12.5

USC allowed 4.4 touchdowns per interception (31 TDs allowed, and 7 INT) in the 2023 season– worst in the Big Ten; Average: 1.6

Notre Dame Defensive Stats & Trends

USC is 9-1 (.900) when rushing more than 30 times since the 2024 season– 9th-best among Power Conference Teams; Average: .678

USC is 10-4 (.714) when having a turnover margin within one of the opposing team since the 2024 season– T-27th-best in FBS; Average: .541

USC was 2-5 (.250) when not forcing a fumble in the 2023 season– T-11th-worst among Power Conference Teams; Average: .513

USC is 7-3 (.700) when committing less than 60 yards in penalties since the 2024 season– T-28th-best in FBS; Average: .528


Bet now on Notre Dame vs USC and all games with BetMGM


More College Football Betting at BetMGM

BetMGM is the best online sportsbook for college football betting.

Whether youโ€™re a first-time bettor checking out the best sportsbook promos, a casual fan betting on Georgia football national championship odds, Michigan football odds, or Ohio State playoff odds, or a longtime diehard breaking down trends for live sports betting, there are entertainment options for everyone.

Visit the sportsbook today to place a college football bet online!

The content provided in this blog is intended for entertainment purposes only. All views and opinions expressed are the authors and reflect their individual perspectives on sports, betting, and related topics. This content should not be considered professional betting advice or the official views of BetMGM LLC. Please gamble responsibly. If you or someone you know is experiencing issues related to gambling, seek help from a licensed health professional. This blog is not liable for any losses, damages, or consequences resulting from betting activities.

About the Author Read More @BETMGM

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.