Wisconsin vs Penn State Prediction, Odds & Best Prop Bets – NCAAF, Week 4

A general view of the end zone at Beaver Stadium before an NCAA college football game against Nebraska, Saturday, Nov. 22, 2025, in State College, Pa. (AP Photo/Barry Reeger)
(AP Photo/Barry Reeger)
Odds Boost This Weekend
  • The Penn State Nittany Lions are a -10.5 point favorite vs. the Wisconsin Badgers
  • Wisconsin vs. Penn State Total (Over/Under): 45.5 points
  • TV Channel: PEAC

Wisconsin (2-1) visit West Shore Home Field at Beaver Stadium to take on Penn State (3-0) on Sep. 26 in University Park, PA. Kickoff is scheduled for 5:00 pm.

The Penn State Nittany Lions are betting favorites in Week 4, with the spread sitting at -10.5 (+100).

The Wisconsin vs. Penn State Over/Under is 45.5 total points.

Bet now on Penn State Nittany Lions vs Wisconsin Badgers & all NCAAF games with BetMGM

Wisconsin vs. Penn State Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
Wisconsin+10.5 -13545.5 -130+290
Penn State -10.5 +10045.5 -102-375

Wisconsin vs Penn State Prediction:

The winning team model predicts Penn State will win this game with 68.2% confidence, based on game simulations, offensive & defensive matchups and recent game results.

The winning team prediction factors in up-to-date player injuries for both the Wisconsin Badgers and the Penn State Nittany Lions, key player performances this season and recent team trends.

Wisconsin vs Penn State Spread Prediction:

Based on recent against-the-spread trends, the model predicts Penn State will cover the spread with 63.5% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


Bet now on Penn State Nittany Lions vs Wisconsin Badgers and all games with BetMGM


  • Wisconsin has hit the Game Total Under in 9 of their last 11 games (+6.85 Units / 57% ROI)
  • Wisconsin has hit the 1H Game Total Under in their last 5 away games (+5.05 Units / 93% ROI)
  • Wisconsin have covered the 1H Spread in 4 of their last 5 away games (+2.90 Units / 52% ROI)
  • Wisconsin have covered the Spread in 3 of their last 5 away games (+0.80 Units / 15% ROI)
  • Wisconsin has hit the Team Total Over in 3 of their last 5 away games (+0.70 Units / 12% ROI)
  • Penn State has hit the 1H Moneyline in 4 of their last 6 games at home (+3.00 Units / 0% ROI)
  • Penn State has hit the Team Total Over in 8 of their last 13 games (+2.35 Units / 16% ROI)
  • Penn State have covered the Spread in 4 of their last 6 games at home (+1.80 Units / 27% ROI)
  • Penn State has hit the 1Q Game Total Under in 4 of their last 6 games at home (+1.65 Units / 23% ROI)
  • Penn State has hit the Game Total Over in 7 of their last 13 games (+1.50 Units / 11% ROI)

Wisconsin Against the Spread (ATS) Record

Wisconsin Badgers is 1-2 against the spread this college football season (-1.2 Units / -36.36% ROI).

  • Wisconsin is 1-1 when betting on the Moneyline for +0 Units / 0% ROI
  • Wisconsin is 2-1 when betting the Over for +0.9 Units / 26.87% ROI
  • Wisconsin is 1-2 when betting the Under for -1.15 Units / -35.38% ROI

Penn State Against the Spread (ATS) Record

Penn State Nittany Lions is 2-1 against the spread this college football season (+0.9 Units / 27.44% ROI).

  • Penn State is 2-0 when betting on the Moneyline for +2 Units / 4.65% ROI
  • Penn State is 1-2 when betting the Over for -1.2 Units / -36.36% ROI
  • Penn State is 2-1 when betting the Under for +0.9 Units / 27.27% ROI

Wisconsin: Keys to the Game vs. Penn State

Wisconsin was winless (0-5) when allowing 200 or more passing yards last season– T-worst among Power Conference Teams; Average: .498

Wisconsin was winless (0-5) when allowing 200 or more passing yards last season– T-worst in FBS; Average: .481

Wisconsin was 1-6 (.143) when the opposing team converts 55% or more of its red zone chances into touchdowns last season– 9th-worst among Power Conference Teams; Average: .451

Wisconsin is 4-5 (.444) when rushing more than 30 times this season– T-11th-worst among Power Conference Teams; Average: .672

Penn State: Keys to the Game vs. Wisconsin

Penn State was 7-1 (.875) when sacking the QB less than 3 times last season– T-best among Power Conference Teams; Average: .468

Penn State was 7-1 (.875) when sacking the QB less than 3 times last season– T-2nd-best in FBS; Average: .429

Penn State is 1-5 (.167) when throwing at least 1 interception this season– T-10th-worst among Power Conference Teams; Average: .436

Penn State was 8-1 (.889) when making 5 or more explosive passes in a game last season– T-4th-best among Power Conference Teams; Average: .631

Matchup Notes for Wisconsin vs. Penn State

Penn State’s WRs has 156 receptions in 16 games (just 9.8 per game) since the 2024 season — 4th-worst among Big Ten WRs. Wisconsin’s defense has allowed 19.5 receptions per game since the 2024 season — T-4th-worst among Big Ten defenses.

Penn State’s WRs has averaged 13.9 yards after the catch since the 2024 season — 5th-best among Big Ten WRs. Wisconsin’s defense has allowed just 8.0 RAC to TEs since the 2024 season — 4th-best among FBS defenses.

Penn State’s TEs has averaged 7.0 targets per game since the 2024 season — 3rd-highest among Big Ten TEs. Wisconsin’s defense has allowed 3.9 receptions per game to TEs since the 2024 season — T-17th-worst among FBS defenses.

Wisconsin’s WRs gained 1,001 yards on 90 receptions (just 11.1 YPR) last season — T-4th-worst among Power 5 WRs. Penn State’s defense allowed just 10.4 Yards Per Reception last season — T-16th-best among FBS defenses.

Wisconsin’s QBs threw for 1,613 passing yards in 12 games (just 134.4 YPG) last season — 7th-worst among FBS teams. Penn State’s defense allowed just 184.2 passing yards per game last season — T-21st-best among FBS defenses.

Wisconsin’s WRs gained 1,001 yards on 90 receptions (just 11.1 YPR) last season — T-2nd-worst among Big Ten WRs. Penn State’s defense allowed just 10.4 Yards Per Reception last season — T-5th-best among Big Ten defenses.

Wisconsin Offensive Stats & Trends

Wisconsin Skill Players averaged 21.5 yards per reception (86 yards/4 catches) on 3rd and short last season– best among Big Ten Teams; Average: 8.5

Wisconsin WRs have averaged a touchdown every 22.5 receptions (90 Rec/4 TDs) this season– worst Receptions Per TD among Big Ten Teams; Average: 9.9

Wisconsin WRs averaged 24.7 yards per reception (222 yards/9 catches) in short yardage situations last season– best among Big Ten Teams; Average: 10.7

Wisconsin Skill Players averaged 18.8 yards per reception (245 yards/13 catches) in short yardage situations last season– best among Big Ten Teams; Average: 9.9

Wisconsin WRs have averaged just 7.5 receptions per game (90/12) this season– T-worst among Power Conference Teams; Average: 12.6

Penn State Offensive Stats & Trends

Penn State TEs averaged 7.9 receptions per game (127/16) last season– best among Power Conference Teams; Average: 3.7

Penn State TEs had 6 receptions for 20 or more yards in the 4th quarter last season– T-2nd-most among FBS Teams

Penn State TEs averaged 7.9 receptions per game (127/16) last season– 3rd-best among FBS Teams; Average: 3.4

Penn State TEs had 127 receptions last season– most among Power Conference Teams

Penn State TEs were targeted 169 times last season– most among Power Conference Teams

Wisconsin Defensive Stats & Trends

Wisconsin intercepted 4 of 323 attempts (80.8 pass attempts per int.) last season– 3rd-worst among Power Conference Teams; Average: 34.9

Wisconsin did not record a sack (39 pass attempts) in the Red Zone in the 2023 season– T-worst in FBS; Average: 15.1

Wisconsin tackled opponents for a loss on just 44 of 428 rushing attempts (10% TFL%) last season– 2nd-worst among Power Conference Teams; Average: 16%.

Wisconsin did not record a sack (39 pass attempts) in the Red Zone in the 2023 season– T-worst among Power Conference Teams; Average: 14.2

Wisconsin intercepted 4 of 323 attempts (80.8 pass attempts per int.) last season– 2nd-worst in the Big Ten; Average: 36.1

Penn State Defensive Stats & Trends

Penn State sacked opposing QBs on 15% of pass attempts (50/340) in the 2023 season– best in the Big Ten; Average: 8%

Penn State allowed 10 rushing TDs on 534 carries (53.4 Carries Per TD) last season– 3rd-best in FBS; Average: 23.2

Penn State’s opponents has attempted two-point conversions on 19% of PATs this season– highest in the Big Ten; Average: 6%

Penn State sacked opposing QBs on 15% of pass attempts (50/340) in the 2023 season– best in FBS; Average: 7%

Penn State allowed 7 rushing TDs on 58 carries (8.3 Carries Per TD) in the Red Zone last season– 2nd-best among Power Conference Teams; Average: 4.8


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