• The Guardians are -175 favorites vs the Angels
• Angels vs Guardians Over / Under today: 8 Runs
• Angels / Guardians TV Channel: GDTV | ESUN | ANTV

The Los Angeles Angels (+145) visit Progressive Field to take on the Cleveland Guardians (-175) on May 11, 2026. First pitch is scheduled for 6:10 pm in Cleveland, OH.

This season, the Angels are 16-25 against the spread (ATS), while the Guardians are 21-21 ATS.

Angels vs Guardians Starting Pitchers Today:

• Angels starting pitcher: Samuel Aldegheri 1-0, 4.77 ERA
• Guardians starting pitcher: Joey Cantillo 2-1, 3.46 ERA

Angels vs. Guardians Odds, Run Line, Over/Under & Moneyline

Angels vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Monday‘s MLB game with 66.5% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Angels players for Monday‘s game, looking at profitable historical betting trends:

Best Angels Player Prop Bets Today:

• Oswald Peraza has hit the Home Runs Over in 4 of his last 8 away games (+25.10 Units / 314% ROI)
• Jo Adell has hit the Singles Over in 17 of his last 25 away games (+11.85 Units / 46% ROI)
• Jo Adell has hit the Runs Under in 16 of his last 20 games (+9.65 Units / 29% ROI)
• Jo Adell has hit the Hits Over in 13 of his last 15 away games (+9.15 Units / 30% ROI)
• Bryce Teodosio has hit the Total Bases Under in 12 of his last 15 away games (+8.45 Units / 42% ROI)

And here are some favorite MLB player prop bets for Guardians players for Monday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Best Bets Today:

• Kyle Manzardo has hit the Hits Runs and RBIs Under in 19 of his last 25 games at home (+12.00 Units / 37% ROI)
• Daniel Schneemann has hit the Total Bases Over in 19 of his last 25 games (+12.00 Units / 36% ROI)
• Kyle Manzardo has hit the Runs Under in 14 of his last 15 games at home (+11.95 Units / 41% ROI)
• Daniel Schneemann has hit the Hits Over in 19 of his last 25 games (+10.20 Units / 28% ROI)
• Daniel Schneemann has hit the Home Runs Over in 2 of his last 10 games at home (+8.90 Units / 89% ROI)

Angels Best Bets Today:

• The Los Angeles Angels have hit the Team Total Under in 28 of their last 45 away games (+10.00 Units / 19% ROI)
• The Los Angeles Angels have hit the Game Total Under in 9 of their last 11 games (+6.80 Units / 56% ROI)
• The Los Angeles Angels have hit the 1st Five Innings (F5) Team Total Over in 19 of their last 30 games (+6.30 Units / 17% ROI)
• The Los Angeles Angels have covered the 1st Five Innings (F5) Run Line in 24 of their last 40 games (+5.30 Units / 11% ROI)
• The Los Angeles Angels have hit the 1st Five Innings (F5) Moneyline in 19 of their last 40 games (+4.70 Units / 10% ROI)

Guardians Best Bets Today:

• The Cleveland Guardians have covered the Run Line in 23 of their last 40 games at home (+10.25 Units / 21% ROI)
• The Cleveland Guardians have hit the Game Total Under in 24 of their last 40 games at home (+8.45 Units / 19% ROI)
• The Cleveland Guardians have hit the Moneyline in 25 of their last 40 games at home (+6.90 Units / 14% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in 9 of their last 11 games (+6.55 Units / 48% ROI)
• The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 18 of their last 30 games (+5.90 Units / 18% ROI)

Angels Against the Spread (ATS) Record

Against the spread this season, the Angels are 19-21 against the Run Line (-8 Units / -14.56% ROI).

• 16-25 when betting on the Moneyline for -5.55 Units / -12.69% ROI
• 19-21 when betting on the total runs Over for -3.85 Units / -8.48% ROI
• 21-19 when betting on the total runs Under for +0.6 Units / 1.34% ROI

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 21-21 against the Run Line (-0.2 Units / -0.38% ROI).

• 21-21 when betting on the Moneyline for -0.1 Units / -0.2% ROI
• 21-21 when betting on the total runs Over for -1.95 Units / -4.23% ROI
• 21-21 when betting on the total runs Under for -2.25 Units / -4.84% ROI

Guardians vs Angels Home Run Prop Bets Today

Guardians vs Angels Total Hits Prop Bets Today

Guardians vs Angels Strikeout Prop Bets Today

Angels Keys to the Game vs. the Guardians

The Angels are just 16-22 (.421) when allowing 5 or more extra base hits this season — tied for 2nd lowest in MLB; League Avg: .532.

The Angels are just 1-8 (.111) when allowing 10 or more hits this season — tied for 5th lowest in MLB; League Avg: .245.

The Angels are just 0-20 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .051.

The Angels are just 16-25 (.390) this season — tied for 2nd lowest in MLB; League Avg: .500.

Guardians Keys to the Game vs. the Angels

The Guardians are just 0-19 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .051.

The Guardians are 13-7 (.650) after a loss this season — 4th best in MLB; League Avg: .471.

The Guardians are 15-1 (.938) when leading entering the 7th inning this season — 4th best in MLB; League Avg: .861.

The Guardians are 41-5 (.872) when they’ve had 10 or more hits since the 2025 season — 2nd best in MLB; League Avg: .745.

Angels Hitting Stats & Trends

Angels hitters have struck out in 26% of their PA’s against RHP this season — highest in MLB.

Angels hitters are slugging just .329 at home this season — 3rd lowest in MLB.

The Angels are batting just .213 at home this season — lowest in MLB.

Angels hitters have an OPS of just .623 (650 PA’s) at home this season — 3rd lowest in MLB.

Guardians Hitting Stats & Trends

Guardians hitters are slugging just .352 against RHP this season — 3rd lowest in MLB.

8% of Guardians’ hitters plate appearances have lasted only one pitch (129/1,584 PA’s) this season — lowest in MLB.

Guardians hitters are averaging 4.08 pitches per plate appearance this season — highest in MLB.

Guardians hitters have chased 23% of pitches out of the zone in righty-righty matchups this season — lowest in MLB.

Angels Pitching Stats & Trends

Opponents have a miss rate of 28% against Angels pitchers this season — tied for best in MLB.

Angels pitchers have walked 12% of batters this season — tied for 3rd highest in MLB.

Angels pitchers have a first-pitch strike rate of just 57% this season — 3rd lowest in MLB.

The Angels have allowed 1.83 runs per game (75/41) in late innings this season — 2nd highest in MLB.

Guardians Pitching Stats & Trends

Guardians pitchers have a strikeout rate of 34% in close and late situations this season — best in MLB.

Guardians pitchers have struck out 28% of left-handed batters they faced this season — best in MLB.

Opponents have a miss rate of 28% against Guardians pitchers this season — tied for 4th best in MLB.

Guardians pitchers have a strikeout rate of 25% this season — 4th best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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