• The Angels are +100 favorites vs the Mariners
• Angels vs Mariners Over / Under today: 6.5 Runs
• Angels / Mariners TV Channel: MRTV | ABTV

The Los Angeles Angels (+100) visit T-Mobile Park to take on the Seattle Mariners (-120) on September 25, 2026. First pitch is scheduled for 10:10 pm in Seattle, WA.

This season, the Angels are 61-98 against the spread (ATS), while the Mariners are 58-100 ATS.

Angels vs Mariners Starting Pitchers Today:

• Angels starting pitcher: Reid Detmers 6-8, 3.52 ERA
• Mariners starting pitcher: Bryce Miller 4-9, 4.02 ERA

Angels vs. Mariners Odds, Run Line, Over/Under & Moneyline

Angels vs Mariners Prediction for Today’s Game

Based on recent trends the model predicts the Mariners will win Friday‘s MLB game with 55.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Angels players for Friday‘s game, looking at profitable historical betting trends:

Best Angels Player Prop Bets Today:

• Vaughn Grissom has hit the Home Runs Over in 2 of his last 5 away games (+11.20 Units / 224% ROI)
• Wade Meckler has hit the Hits Runs and RBIs Over in 17 of his last 25 games (+10.50 Units / 37% ROI)
• Wade Meckler has hit the Singles Over in 18 of his last 25 away games (+10.15 Units / 34% ROI)
• Reid Detmers has hit the Walks Allowed Under in 17 of his last 25 games (+9.60 Units / 33% ROI)
• Zach Neto has hit the Hits Under in 12 of his last 20 games (+8.80 Units / 39% ROI)

And here are some favorite MLB player prop bets for Mariners players for Friday‘s game, looking at profitable historical betting trends:

Best Mariners Player Prop Best Bets Today:

• J.P. Crawford has hit the Hits Runs and RBIs Under in 20 of his last 25 games at home (+12.85 Units / 37% ROI)
• Dominic Canzone has hit the Hits Over in 16 of his last 20 games (+12.00 Units / 35% ROI)
• Randy Arozarena has hit the Walks Over in 11 of his last 15 games at home (+11.25 Units / 75% ROI)
• Dominic Canzone has hit the Singles Over in 16 of his last 25 games at home (+9.25 Units / 37% ROI)
• J.P. Crawford has hit the Total Bases Under in 15 of his last 25 games at home (+9.25 Units / 34% ROI)

Angels Best Bets Today:

• The Los Angeles Angels have hit the Game Total Under in 30 of their last 50 games (+9.70 Units / 17% ROI)
• The Los Angeles Angels have covered the Run Line in 14 of their last 18 away games (+9.05 Units / 35% ROI)
• The Los Angeles Angels have hit the Team Total Under in 19 of their last 30 away games (+6.85 Units / 20% ROI)
• The Los Angeles Angels have hit the 1st Five Innings (F5) Team Total Over in 6 of their last 8 games (+3.75 Units / 39% ROI)
• The Los Angeles Angels have hit the 1st Five Innings (F5) Moneyline in 8 of their last 18 away games (+1.80 Units / 10% ROI)

Mariners Best Bets Today:

• The Seattle Mariners have hit the Game Total Over in 25 of their last 40 games (+10.65 Units / 24% ROI)
• The Seattle Mariners have hit the 1st Five Innings (F5) Team Total Over in 25 of their last 40 games (+8.45 Units / 17% ROI)
• The Seattle Mariners have hit the 1st Five Innings (F5) Moneyline in 5 of their last 7 games (+3.45 Units / 29% ROI)
• The Seattle Mariners have hit the Team Total Under in 25 of their last 45 games at home (+3.45 Units / 7% ROI)
• The Seattle Mariners have covered the 1st Five Innings (F5) Run Line in 4 of their last 7 games (+0.95 Units / 12% ROI)

Angels Against the Spread (ATS) Record

Against the spread this season, the Angels are 79-79 against the Run Line (-24 Units / -10.87% ROI).

• 61-98 when betting on the Moneyline for -26 Units / -15.42% ROI
• 68-87 when betting on the total runs Over for -27.15 Units / -15.53% ROI
• 87-68 when betting on the total runs Under for +12.4 Units / 7.08% ROI

Mariners Against the Spread (ATS) Record

Against the spread this season, the Mariners are 58-100 against the Run Line (-40.05 Units / -21.68% ROI).

• 74-85 when betting on the Moneyline for -35 Units / -16.35% ROI
• 83-67 when betting on the total runs Over for +9.4 Units / 5.35% ROI
• 67-83 when betting on the total runs Under for -23.85 Units / -13.68% ROI

Angels Keys to the Game vs. the Mariners

The Angels are just 53-11 (.828) when leading entering the 9th inning this season — lowest in MLB.

The Angels are just 5-18 (.217) when tied entering the 7th inning this season — 2nd lowest in MLB.

The Angels are just 23-37 (.383) vs the bottom 10 runs allowed teams this season Today, they face the Mariners (16th fewest runs allowed).

The Angels are just 4-16 (.200) when tied entering the 8th inning this season — lowest in MLB.

Mariners Keys to the Game vs. the Angels

The Mariners are just 2-72 (.027) when trailing entering the 8th inning this season — 2nd lowest in MLB.

The Mariners are just 23-26 (.469) when they’ve scored in the first inning this season — 2nd lowest in MLB.

The Mariners are just 2-75 (.026) when trailing entering the 9th inning this season — tied for 3rd lowest in MLB.

The Mariners are just 26-40 (.394) vs bottom 10 scoring offenses this season Today, they face the Angels (29th in runs scored).

Angels Hitting Stats & Trends

Angels hitters are slugging just .327 at home this season — lowest in MLB.

Angels hitters are slugging just .363 against RHP this season — lowest in MLB.

Angels hitters have struck out in 26% of their PA’s against RHP this season — highest in MLB.

Angels hitters have an OPS of just .625 (2,974 PA’s) at home this season — lowest in MLB.

Mariners Hitting Stats & Trends

Mariners hitters are slugging just .477 on the first pitch of at-bats this season — lowest in MLB.

The Mariners are batting just .220 at home this season — lowest in MLB.

The Mariners are just 58-101 (.365) against the run line (-22.8% ROI) this season — lowest in MLB.

The Mariners are just 22-44 (.333) against the run line (-25.2% ROI) vs bottom 10 scoring offenses this season Today, they face the Angels (29th in runs scored).

Angels Pitching Stats & Trends

Opponents have a miss rate of 28% against Angels pitchers this season — 3rd best in MLB.

Angels pitchers have walked 10% of batters this season — 3rd highest in MLB.

The Angels have won just 20% of games in which their opponents scored first this season — lowest in MLB.

Angels pitchers have won only 17% of games in which they have allowed their opponent to score in three different innings this season — lowest in MLB.

Mariners Pitching Stats & Trends

Mariners pitchers have walked 7% of batters this season — 2nd best in MLB.

Mariners pitchers have a first-pitch strike rate of 66% this season — highest in MLB.

Mariners pitchers have thrown at least two strikes in their first three pitches to 69% of opposing batters this season — highest in MLB.

Mariners pitchers have walked 7% of batters when facing the leadoff batter in the inning this season — tied for 3rd best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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