Arizona Diamondbacks vs Chicago White Sox Prediction, Odds & Player Prop Bets Today – MLB, Jun 25

  • The Arizona Diamondbacks are -140 favorites vs the Chicago White Sox
  • Arizona Diamondbacks vs Chicago White Sox Over / Under today: 8.5 Runs
  • Arizona Diamondbacks / Chicago White Sox TV Channel: DBTV | CHSN

The Arizona Diamondbacks (-145) visit Rate Field to take on the Chicago White Sox (+120) on Wednesday, June 25, 2025. First pitch is scheduled for 2:10pm EDT in Chicago, IL, IL.

This season, the Arizona Diamondbacks are 41-38 against the spread (ATS), while the Chicago White Sox are 45-35 ATS.

Arizona Diamondbacks vs Chicago White Sox Starting Pitchers Today:

  • Arizona Diamondbacks starting pitcher: , ERA
  • Chicago White Sox starting pitcher: , ERA

Arizona Diamondbacks vs. Chicago White Sox Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Arizona Diamondbacks-1.5 +110O 8.5 -105-145
Chicago White Sox +1.5 -135U 8.5 -115+120

Arizona Diamondbacks vs Chicago White Sox Prediction for Today’s Game

Based on recent trends the model predicts the will win Wednesday‘s MLB game with confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Arizona Diamondbacks players for Wednesday‘s game, looking at profitable historical betting trends:

Best Arizona Diamondbacks Player Prop Bets Today:

  • Lourdes Gurriel Jr. has hit the Runs Under in 20 of his last 25 games (+12.65 Units / 31% ROI)
  • Lourdes Gurriel Jr. has hit the Hits Over in 19 of his last 25 games (+11.70 Units / 24% ROI)
  • Pavin Smith has hit the Home Runs Over in 3 of his last 10 games (+9.90 Units / 99% ROI)
  • Ketel Marte has hit the Singles Over in 15 of his last 20 games (+8.90 Units / 36% ROI)
  • Ildemaro Vargas has hit the Total Bases Under in 8 of his last 10 games (+7.50 Units / 57% ROI)

And here are some favorite MLB player prop bets for Chicago White Sox players for Wednesday‘s game, looking at profitable historical betting trends:

Best Chicago White Sox Player Prop Best Bets Today:

  • Josh Rojas has hit the Total Bases Under in 16 of his last 20 games at home (+12.65 Units / 58% ROI)
  • Josh Rojas has hit the Hits Under in 16 of his last 20 games at home (+12.55 Units / 58% ROI)
  • Josh Rojas has hit the Singles Under in 17 of his last 20 games at home (+11.35 Units / 31% ROI)
  • Josh Rojas has hit the Hits Runs and RBIs Under in 14 of his last 20 games at home (+8.50 Units / 34% ROI)
  • Andrew Benintendi has hit the Home Runs Over in 2 of his last 5 games (+8.40 Units / 168% ROI)
  • The Arizona Diamondbacks have hit the 1st Five Innings (F5) Moneyline in 36 of their last 63 games (+16.45 Units / 18% ROI)
  • The Arizona Diamondbacks have covered the 1st Five Innings (F5) Run Line in 40 of their last 63 games (+15.20 Units / 20% ROI)
  • The Arizona Diamondbacks have hit the Team Total Under in 20 of their last 31 away games (+7.70 Units / 21% ROI)
  • The Arizona Diamondbacks have covered the Run Line in 14 of their last 21 games (+7.50 Units / 28% ROI)
  • The Arizona Diamondbacks have hit the Moneyline in 14 of their last 21 games (+7.10 Units / 25% ROI)
  • The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 27 of their last 39 games at home (+13.10 Units / 27% ROI)
  • The Chicago White Sox have hit the Team Total Over in 18 of their last 26 games at home (+9.10 Units / 30% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Moneyline in 22 of their last 56 games (+8.75 Units / 15% ROI)
  • The Chicago White Sox have hit the Game Total Over in 21 of their last 36 games at home (+7.70 Units / 19% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Under in 41 of their last 71 games (+7.24 Units / 9% ROI)

Arizona Diamondbacks Against the Spread (ATS) Record

Against the spread this season, the Arizona Diamondbacks are 39-40 against the Run Line (-5.71 Units / -5.63% ROI).

  • 41-38 when betting on the Moneyline for -6.05 Units / -5.58% ROI
  • 39-36 when betting on the total runs Over for -0.8 Units / -0.91% ROI
  • 36-39 when betting on the total runs Under for -6.4 Units / -7.43% ROI

Chicago White Sox Against the Spread (ATS) Record

Against the spread this season, the Chicago White Sox are 45-35 against the Run Line (+4 Units / 4.12% ROI).

  • 25-55 when betting on the Moneyline for -16.16 Units / -20.17% ROI
  • 36-39 when betting on the total runs Over for -7.1 Units / -8.05% ROI
  • 39-36 when betting on the total runs Under for -0.85 Units / -0.97% ROI

Chicago White Sox vs Arizona Diamondbacks Home Run Prop Bets Today

Over Under
Ketel Marte (ARI) 0.5 +360 0.5 -500
Pavin Smith (ARI) 0.5 +450 0.5 -625
Miguel Vargas (CWS) 0.5 +450 0.5 -625
Randal Grichuk (ARI) 0.5 +475 0.5 -700
Luis Robert (CWS) 0.5 +475 0.5 -700

Chicago White Sox vs Arizona Diamondbacks Total Hits Prop Bets Today

Over Under
Ketel Marte (ARI) 0.5 -275 0.5 +195
Lourdes Gurriel Jr (ARI) 0.5 -250 0.5 +190
Chase Meidroth (CWS) 0.5 -210 0.5 +160
Andrew Benintendi (CWS) 0.5 -210 0.5 +160
Jake McCarthy (ARI) 0.5 -210 0.5 +160

Chicago White Sox vs Arizona Diamondbacks RBI Prop Bets Today

Over Under
Lourdes Gurriel Jr (ARI) 0.5 +140 0.5 -190
Ketel Marte (ARI) 0.5 +150 0.5 -200
Randal Grichuk (ARI) 0.5 +160 0.5 -210
Andrew Benintendi (CWS) 0.5 +160 0.5 -220
Miguel Vargas (CWS) 0.5 +175 0.5 -225

Chicago White Sox vs Arizona Diamondbacks Strikeout Prop Bets Today

Over Under
Zac Gallen (ARI) 5.5 -110 5.5 -115
Sean Burke (CWS) 4.5 +110 4.5 -145

starting pitcher – away

Chicago White Sox Starting Pitcher Stats & Trends

starting pitcher – home

Arizona Diamondbacks Keys to the Game vs. the Chicago White Sox

keys to the game – away

Chicago White Sox Keys to the Game vs. the Arizona Diamondbacks

keys to the game – home

team hitters – away

team hitters – home

team pitchers – away

team pitchers – home

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.