• The Astros are -115 favorites vs the Athletics
• Astros vs Athletics Over / Under today: 10 Runs
• Astros / Athletics TV Channel: NSCA | SCHN

The Houston Astros (-115) visit Sutter Health Park to take on the Athletics (-105) on April 4, 2026. First pitch is scheduled for 4:05 pm in Sacramento, CA.

This season, the Astros are 5-3 against the spread (ATS), while the Athletics are 4-3 ATS.

Astros vs Athletics Starting Pitchers Today:

• Astros starting pitcher: , ERA
• Athletics starting pitcher: , ERA

Astros vs. Athletics Odds, Run Line, Over/Under & Moneyline

Astros vs Athletics Prediction for Today’s Game

Based on recent trends the model predicts the will win Saturday‘s MLB game with confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Astros vs Athletics and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Astros players for Saturday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Bets Today:

• player high – away 

And here are some favorite MLB player prop bets for Athletics players for Saturday‘s game, looking at profitable historical betting trends:

Best Athletics Player Prop Best Bets Today:

• player  high – home

Astros Best Bets Today:

• team high – away

Athletics Best Bets Today:

• team high – home

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 5-3 against the Run Line (+3.3 Units / 36.67% ROI).

• 5-3 when betting on the Moneyline for +0.8 Units / 7.24% ROI
• 6-2 when betting on the total runs Over for +3.7 Units / 40.88% ROI
• 2-6 when betting on the total runs Under for -4.45 Units / -52.05% ROI

Athletics Against the Spread (ATS) Record

Against the spread this season, the Athletics are 4-3 against the Run Line (-0.45 Units / -4.33% ROI).

• 2-5 when betting on the Moneyline for -2.65 Units / -37.32% ROI
• 2-5 when betting on the total runs Over for -3.45 Units / -44.81% ROI
• 5-2 when betting on the total runs Under for +2.85 Units / 37.01% ROI

Astros Keys to the Game vs. the Athletics

Athletics Keys to the Game vs. the Astros

Astros Hitting Stats & Trends

Athletics Hitting Stats & Trends

Astros Pitching Stats & Trends

Athletics Pitching Stats & Trends

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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