- The Diamondbacks are -150 favorites vs the Astros
- Astros vs Diamondbacks Over / Under today: 9 Runs
- Astros / Diamondbacks TV Channel: DBTV | SCHN
The Houston Astros (+115) visit Chase Field to take on the Arizona Diamondbacks (-140) on Monday, July 21, 2025. First pitch is scheduled for 9:40pm EDT in Phoenix, AZ.
This season, the Astros are 57-42 against the spread (ATS), while the Diamondbacks are 49-51 ATS.
Astros vs Diamondbacks Starting Pitchers Today:
- Astros starting pitcher: Colton Gordon 3-2, 4.74 ERA
- Diamondbacks starting pitcher: Zac Gallen 7-10, 5.40 ERA
Astros vs. Diamondbacks Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Astros | +1.5 -175 | O 9 -118 | +115 |
| Diamondbacks | -1.5 +145 | U 9 -102 | -140 |
Astros vs Diamondbacks Prediction for Today’s Game
Based on recent trends the model predicts the Diamondbacks will win Monday‘s MLB game with 58.9% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
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We’ve highlighted some favorite MLB player prop bets for Astros players for Monday‘s game, looking at profitable historical betting trends:
Best Astros Player Prop Bets Today:
- Christian Walker has hit the Singles Over in 15 of his last 20 away games (+11.75 Units / 57% ROI)
- Christian Walker has hit the RBIs Over in 8 of his last 10 games (+10.90 Units / 107% ROI)
- Mauricio Dubon has hit the Total Bases Over in 12 of his last 15 away games (+10.60 Units / 54% ROI)
- Christian Walker has hit the Hits Over in 16 of his last 20 away games (+10.45 Units / 28% ROI)
- Christian Walker has hit the Runs Under in 16 of his last 20 games (+9.35 Units / 29% ROI)
And here are some favorite MLB player prop bets for Diamondbacks players for Monday‘s game, looking at profitable historical betting trends:
Best Diamondbacks Player Prop Best Bets Today:
- Eugenio Suarez has hit the Home Runs Over in 5 of his last 10 games at home (+16.10 Units / 161% ROI)
- Eugenio Suarez has hit the Total Bases Over in 17 of his last 25 games (+11.85 Units / 43% ROI)
- James McCann has hit the Hits Runs and RBIs Over in 15 of his last 20 games (+11.65 Units / 48% ROI)
- Corbin Carroll has hit the Singles Under in 19 of his last 25 games at home (+11.15 Units / 32% ROI)
- Eugenio Suarez has hit the RBIs Over in 14 of his last 25 games (+9.25 Units / 36% ROI)
Astros Best Bets Today:
- The Houston Astros have hit the Team Total Under in 59 of their last 99 games (+15.55 Units / 13% ROI)
- The Houston Astros have hit the Moneyline in 40 of their last 64 games (+13.00 Units / 15% ROI)
- The Houston Astros have hit the 1st Five Innings (F5) Team Total Under in 29 of their last 44 away games (+12.95 Units / 25% ROI)
- The Houston Astros have covered the Run Line in 48 of their last 91 games (+6.27 Units / 5% ROI)
- The Houston Astros have hit the Game Total Over in 9 of their last 13 games (+5.80 Units / 41% ROI)
Diamondbacks Best Bets Today:
- The Arizona Diamondbacks have hit the 1st Five Innings (F5) Moneyline in 47 of their last 84 games (+17.50 Units / 15% ROI)
- The Arizona Diamondbacks have covered the 1st Five Innings (F5) Run Line in 52 of their last 84 games (+16.90 Units / 17% ROI)
- The Arizona Diamondbacks have hit the Game Total Over in 30 of their last 46 games (+12.45 Units / 24% ROI)
- The Arizona Diamondbacks have hit the Team Total Over in 28 of their last 43 games at home (+10.80 Units / 21% ROI)
- The Arizona Diamondbacks have hit the 1st Five Innings (F5) Team Total Over in 35 of their last 59 games (+8.75 Units / 12% ROI)
Astros Against the Spread (ATS) Record
Against the spread this season, the Astros are 50-49 against the Run Line (+1.62 Units / 1.3% ROI).
- 57-42 when betting on the Moneyline for +7 Units / 5.35% ROI
- 43-52 when betting on the total runs Over for -13.55 Units / -12.52% ROI
- 52-43 when betting on the total runs Under for +4.75 Units / 4.33% ROI
Diamondbacks Against the Spread (ATS) Record
Against the spread this season, the Diamondbacks are 49-51 against the Run Line (-7.11 Units / -5.52% ROI).
- 50-50 when betting on the Moneyline for -12.1 Units / -8.98% ROI
- 53-43 when betting on the total runs Over for +5.45 Units / 4.92% ROI
- 43-53 when betting on the total runs Under for -14.8 Units / -13.56% ROI
Diamondbacks vs Astros Home Run Prop Bets Today
| Over | Under | |
|---|---|---|
| Eugenio Suarez (ARI) | 0.5 +275 | 0.5 -350 |
| Ketel Marte (ARI) | 0.5 +310 | 0.5 -400 |
| Christian Walker (HOU) | 0.5 +475 | 0.5 -650 |
| Corbin Carroll (ARI) | 0.5 +575 | 0.5 -900 |
| Lourdes Gurriel Jr (ARI) | 0.5 +600 | 0.5 -900 |
Diamondbacks vs Astros Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Eugenio Suarez (ARI) | 0.5 -250 | 0.5 +190 |
| Corbin Carroll (ARI) | 0.5 -250 | 0.5 +180 |
| Mauricio Dubon (HOU) | 0.5 -235 | 0.5 +175 |
| Josh Naylor (ARI) | 0.5 -225 | 0.5 +170 |
| Victor Caratini (HOU) | 0.5 -220 | 0.5 +165 |
Diamondbacks vs Astros RBI Prop Bets Today
| Over | Under | |
|---|---|---|
| Eugenio Suarez (ARI) | 0.5 +115 | 0.5 -150 |
| Ketel Marte (ARI) | 0.5 +125 | 0.5 -165 |
| Yainer Diaz (HOU) | 0.5 +160 | 0.5 -210 |
| Christian Walker (HOU) | 0.5 +160 | 0.5 -210 |
| Lourdes Gurriel Jr (ARI) | 0.5 +165 | 0.5 -220 |
Diamondbacks vs Astros Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Zac Gallen (ARI) | 5.5 -105 | 5.5 -125 |
| Colton Gordon (HOU) | 3.5 -105 | 3.5 -120 |
Astros Starting Pitcher Stats & Trends
Opponents have a groundball rate of just 25% (9/36) against Colton Gordon’s low breaking balls this season — lowest in MLB among starting pitchers with at least 39 total IP; League Avg: 49% — first Percentile.
Right-handed hitters have a line drive rate of 33% (47/141) against Colton Gordon this season — highest in MLB among starting pitchers with at least 39 total IP; League Avg: 24% — 0 Percentile.
Colton Gordon has walked 4% of batters this season — 5th best in MLB among starting pitchers with at least 39 total IP; League Avg: 8% — 97th Percentile.
Right-handed hitters have a miss rate of just 17% (58/352) against Colton Gordon this season — 3rd lowest in MLB among starting pitchers with at least 39 total IP; League Avg: 25% — second Percentile.
Diamondbacks Starting Pitcher Stats & Trends
Zac Gallen has walked 12% of batters when going through the lineup the first time in a game since last season — highest among qualified SPs in MLB; League Avg: 7% — second Percentile.
Zac Gallen has walked 12% of batters when going through the lineup the first time in a game this season — tied for 2nd highest among qualified SPs in MLB; League Avg: 7% — fourth Percentile.
Zac Gallen has an ERA of 5.66 (55.2 IP) at home this season — 3rd highest among qualified SPs in MLB; League Avg: 3.40 — fifth Percentile.
Zac Gallen has thrown just 47% of his pitches in the strike zone (900/1,894) this season — 7th lowest among qualified SPs in MLB; League Avg: 51% — 10th Percentile.
Astros Keys to the Game vs. the Diamondbacks
The Astros are 19-13 (.594) vs top 10 scoring offenses this season They play the Diamondbacks (Ranks fourth runs scored) today.
The Astros are 39-31 (.557) vs top 10 scoring offenses since last season They play the Diamondbacks (Ranks fourth runs scored) today.
The Astros are 8-3 (.727) when tied entering the 7th inning this season — 4th best in MLB; League Avg: .500.
The Astros were just 0-56 (.000) when trailing entering the 9th inning in the 2024 season — tied for lowest in MLB; League Avg: .050.
Diamondbacks Keys to the Game vs. the Astros
The Diamondbacks are just 46-4 (.920) when leading entering the 9th inning this season — 5th lowest in MLB; League Avg: .956.
The Diamondbacks are just 41-10 (.804) when leading entering the 7th inning this season — 5th lowest in MLB; League Avg: .876.
The Diamondbacks are just 44-8 (.846) when leading entering the 8th inning this season — 5th lowest in MLB; League Avg: .906.
The Diamondbacks were 5-59 (.077) when trailing entering the 9th inning in the 2024 season — 4th best in MLB; League Avg: .050.
Astros Hitting Stats & Trends
Astros hitters have not struck out in 5 PA’s against LHP over the past seven days (2 games) — tied for best in MLB; League Avg: 21%.
Astros hitters have put 46% of balls in play to the left side of the field this season — highest in MLB; League Avg: 38%.
Astros hitters are averaging just 3.70 pitches per plate appearance since last season — lowest in MLB; League Avg: 3.88.
Astros hitters have put just 29% of balls in play to the right side of the field this season — lowest in MLB; League Avg: 37%.
Diamondbacks Hitting Stats & Trends
Diamondbacks hitters are slugging .464 against RHP this season — best in MLB; League Avg: .406.
Diamondbacks hitters have an OPS of .781 (7,079 PA’s) against RHP since last season — 2nd best in MLB; League Avg: .717.
Diamondbacks hitters have 264 extra-base hits out of 622 total hits (42%) against RHP this season — best in MLB; League Avg: 35%.
Diamondbacks hitters are slugging .443 since last season — 2nd best in MLB; League Avg: .400.
Astros Pitching Stats & Trends
Astros pitchers have a strikeout rate of 26% this season — best in MLB; League Avg: 22%.
Opponents have a miss rate of 28% against Astros pitchers since last season — 2nd best in MLB; League Avg: 25%.
Astros pitchers have a strikeout rate of 32% in close and late situations this season — best in MLB; League Avg: 24%.
Opponents have a miss rate of 28% against Astros pitchers this season — best in MLB; League Avg: 25%.
Diamondbacks Pitching Stats & Trends
Diamondbacks pitchers have struck out just 10% of left-handed batters they faced over the last 14 days — lowest in MLB; League Avg: 21%.
The Diamondbacks have allowed 1.69 runs per game (169/100) in late innings this season — 3rd highest in MLB; League Avg: 1.33.
The Diamondbacks pitchers have allowed their opponents to score first in just 42% of their games since last season — lowest in MLB; League Avg: 50%.
Diamondbacks pitchers have a strikeout rate of just 18% over the last 14 days — tied for 4th lowest in MLB; League Avg: 22%.
More MLB Reading:
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