• The Astros are -155 favorites vs the Giants
• Astros vs Giants Over / Under today: 8.5 Runs
• Astros / Giants TV Channel: NSBA | SCHN

The Houston Astros (-155) visit Oracle Park to take on the San Francisco Giants (+125) on August 12, 2026. First pitch is scheduled for 3:45 pm in San Francisco, CA.

This season, the Astros are 61-60 against the spread (ATS), while the Giants are 57-61 ATS.

Astros vs Giants Starting Pitchers Today:

• Astros starting pitcher: Ronel Blanco 0-1, 6.99 ERA
• Giants starting pitcher: Tyler Mahle 3-9, 4.86 ERA

Astros vs. Giants Odds, Run Line, Over/Under & Moneyline

Astros vs Giants Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Wednesday‘s MLB game with 57.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Astros vs Giants and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Astros players for Wednesday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Bets Today:

• Cam Smith has hit the Home Runs Over in 4 of his last 10 away games (+20.00 Units / 200% ROI)
• Taylor Trammell has hit the Runs Over in 13 of his last 25 away games (+10.80 Units / 43% ROI)
• Jeremy Pena has hit the Hits Under in his last 8 games (+10.55 Units / 74% ROI)
• Yordan Alvarez has hit the Total Bases Under in 18 of his last 25 away games (+10.40 Units / 36% ROI)
• Yordan Alvarez has hit the RBIs Under in 19 of his last 25 away games (+8.85 Units / 21% ROI)

And here are some favorite MLB player prop bets for Giants players for Wednesday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Best Bets Today:

• Osleivis Basabe has hit the Home Runs Over in 3 of his last 10 games (+22.00 Units / 220% ROI)
• Bryce Eldridge has hit the Walks Over in 15 of his last 25 games at home (+10.10 Units / 40% ROI)
• Bryce Eldridge has hit the Singles Under in 12 of his last 15 games at home (+7.50 Units / 32% ROI)
• Willy Adames has hit the Hits Over in 9 of his last 10 games at home (+7.30 Units / 47% ROI)
• Willy Adames has hit the Total Bases Over in 9 of his last 10 games at home (+7.30 Units / 47% ROI)

Astros Best Bets Today:

• The Houston Astros have covered the Run Line in 14 of their last 20 games (+10.90 Units / 44% ROI)
• The Houston Astros have hit the Moneyline in 27 of their last 45 away games (+10.05 Units / 21% ROI)
• The Houston Astros have hit the 1st Five Innings (F5) Team Total Under in 20 of their last 30 away games (+7.65 Units / 20% ROI)
• The Houston Astros have hit the Team Total Over in 21 of their last 35 away games (+6.60 Units / 17% ROI)
• The Houston Astros have hit the Game Total Over in 12 of their last 19 away games (+6.50 Units / 31% ROI)

Giants Best Bets Today:

• The San Francisco Giants have hit the 1st Five Innings (F5) Moneyline in 8 of their last 15 games at home (+6.70 Units / 36% ROI)
• The San Francisco Giants have hit the Team Total Under in 27 of their last 45 games (+6.65 Units / 13% ROI)
• The San Francisco Giants have covered the 1st Five Innings (F5) Run Line in 9 of their last 11 games at home (+6.35 Units / 45% ROI)
• The San Francisco Giants have hit the Moneyline in 15 of their last 25 games at home (+5.70 Units / 19% ROI)
• The San Francisco Giants have covered the Run Line in 15 of their last 25 games at home (+4.85 Units / 15% ROI)

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 62-59 against the Run Line (-2.1 Units / -1.29% ROI).

• 61-60 when betting on the Moneyline for -4.9 Units / -3.46% ROI
• 64-50 when betting on the total runs Over for +8.05 Units / 5.99% ROI
• 50-64 when betting on the total runs Under for -20.35 Units / -15.42% ROI

Giants Against the Spread (ATS) Record

Against the spread this season, the Giants are 57-61 against the Run Line (-19.05 Units / -11.43% ROI).

• 50-70 when betting on the Moneyline for -17.55 Units / -13.2% ROI
• 54-55 when betting on the total runs Over for -6.75 Units / -5.09% ROI
• 55-54 when betting on the total runs Under for -4.2 Units / -3.2% ROI

Giants vs Astros Home Run Prop Bets Today

Giants vs Astros Total Hits Prop Bets Today

Giants vs Astros Strikeout Prop Bets Today

Astros Keys to the Game vs. the Giants

The Astros were just 0-56 (.000) when trailing entering the 9th inning in the 2024 season — tied for lowest in MLB; League Avg: .050.

The Astros were 56-7 (.889) when they scored 5 or more runs in the 2025 season — 3rd best in MLB; League Avg: .797.

The Astros were 65-10 (.867) when they scored 5 or more runs in the 2024 season — 5th best in MLB; League Avg: .804.

The Astros were just 5-13 (.278) when tied entering the 8th inning in the 2024 season — 3rd lowest in MLB; League Avg: .500.

Giants Keys to the Game vs. the Astros

The Giants were just 65-6 (.915) when leading entering the 9th inning in the 2025 season — 3rd lowest in MLB; League Avg: .956.

The Giants were 11-65 (.145) when trailing entering the 8th inning in the 2025 season — 2nd best in MLB; League Avg: .090.

The Giants were 12-60 (.167) when trailing entering the 7th inning in the 2025 season — tied for 4th best in MLB; League Avg: .124.

Astros Hitting Stats & Trends

Astros hitters have 38 extra-base hits out of 140 total hits (just 27%) when facing the starting pitcher for the 3rd time in a game this season — 2nd lowest in MLB.

The Astros are batting .273 when facing the starting pitcher for the 3rd time in a game this season — 5th best in MLB.

Astros hitters have struck out in just 20% of their PA’s against LHP this season — 5th best in MLB.

Astros hitters have 77 extra-base hits out of 175 total hits (44%) on the first pitch of at-bats this season — 2nd best in MLB.

Giants Hitting Stats & Trends

The Giants are batting .254 with two outs this season — 2nd best in MLB.

Giants hitters have struck out in just 20% of their PA’s against RHP this season — 4th best in MLB.

30% of Giants hitters strikeouts have come on 95+ MPH fastballs this season — highest in MLB.

The Giants have a winning percentage of just 42% this season — 5th lowest in MLB.

Astros Pitching Stats & Trends

Astros pitchers have walked 11% of batters when facing the leadoff batter in the inning this season — highest in MLB.

Astros pitchers have walked 11% of batters this season — 2nd highest in MLB.

Opponents have a groundball rate of just 39% against Astros pitchers this season — 2nd lowest in MLB.

The Astros have allowed 3.14 runs per game (380/121) in the first 5 innings this season — 3rd highest in MLB.

Giants Pitching Stats & Trends

The Giants have won just 6% of road games in which their opponents scored first this season — lowest in MLB.

Giants pitchers have walked 10% of batters this season — tied for 5th highest in MLB.

Opponents have a groundball rate of 46% against Giants pitchers this season — highest in MLB.

Giants pitchers have a strikeout rate of just 20% this season — 5th lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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