Astros vs Mariners Prediction, Odds & Player Prop Bets Today – MLB, Apr 12

Seattle Mariners' Cal Raleigh walks to first base during the third inning of a baseball game against the Chicago Cubs in Chicago, Sunday, June 22, 2025.
(AP Photo/Nam Y. Huh)
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  • The Mariners are -160 favorites vs the Astros
  • Astros vs Mariners Over / Under today: 7.5 Runs
  • Astros / Mariners TV Channel: MRTV | SCHN

The Houston Astros (+135) visit T-Mobile Park to take on the Seattle Mariners (-160) on April 12, 2026. First pitch is scheduled for 4:10 pm in Seattle, WA.

This season, the Astros are 6-9 against the spread (ATS), while the Mariners are 5-10 ATS.

Astros vs Mariners Starting Pitchers Today:

  • Astros starting pitcher: Cody Bolton 0-0, 3.69 ERA
  • Mariners starting pitcher: Logan Gilbert 0-2, 5.40 ERA

Astros vs. Mariners Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Astros+1.5 -170O 7.5 -105+135
Mariners -1.5 +140U 7.5 -115-160

Astros vs Mariners Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Sunday‘s MLB game with 51.9% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Astros players for Sunday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Bets Today:

  • Carlos Correa has hit the Runs Over in 16 of his last 25 away games (+11.70 Units / 46% ROI)
  • Cam Smith has hit the Home Runs Over in 2 of his last 9 games (+9.50 Units / 106% ROI)
  • Jose Altuve has hit the RBIs Under in 20 of his last 25 away games (+9.25 Units / 16% ROI)
  • Carlos Correa has hit the Hits Over in 16 of his last 25 away games (+8.90 Units / 23% ROI)
  • Yainer Diaz has hit the Total Bases Under in 15 of his last 20 games (+8.05 Units / 26% ROI)

And here are some favorite MLB player prop bets for Mariners players for Sunday‘s game, looking at profitable historical betting trends:

Best Mariners Player Prop Best Bets Today:

  • Julio Rodriguez has hit the Total Bases Under in 20 of his last 25 games (+12.70 Units / 34% ROI)
  • Josh Naylor has hit the Runs Under in 14 of his last 15 games (+12.20 Units / 46% ROI)
  • Josh Naylor has hit the Hits Under in 11 of his last 15 games (+11.65 Units / 66% ROI)
  • Luke Raley has hit the Home Runs Over in 2 of his last 6 games at home (+11.50 Units / 192% ROI)
  • Cal Raleigh has hit the Singles Under in 17 of his last 20 games (+10.00 Units / 22% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 14 of their last 19 games (+8.90 Units / 41% ROI)
  • The Houston Astros have hit the Game Total Over in 11 of their last 13 games (+8.80 Units / 61% ROI)
  • The Houston Astros have hit the Team Total Over in 10 of their last 13 games (+6.05 Units / 37% ROI)
  • The Houston Astros have covered the Run Line in 28 of their last 50 away games (+5.75 Units / 9% ROI)
  • The Houston Astros have covered the 1st Five Innings (F5) Run Line in 19 of their last 35 away games (+0.80 Units / 2% ROI)
  • The Seattle Mariners have hit the Moneyline in 34 of their last 50 games at home (+12.35 Units / 15% ROI)
  • The Seattle Mariners have hit the 1st Five Innings (F5) Moneyline in 23 of their last 40 games at home (+8.50 Units / 12% ROI)
  • The Seattle Mariners have hit the Team Total Over in 27 of their last 45 games at home (+7.30 Units / 14% ROI)
  • The Seattle Mariners have hit the Game Total Over in 26 of their last 45 games at home (+6.45 Units / 13% ROI)
  • The Seattle Mariners have hit the 1st Five Innings (F5) Team Total Over in 26 of their last 45 games at home (+3.65 Units / 6% ROI)

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 7-8 against the Run Line (-0.15 Units / -0.85% ROI).

  • 6-9 when betting on the Moneyline for -6.1 Units / -30.42% ROI
  • 11-4 when betting on the total runs Over for +6.5 Units / 38.81% ROI
  • 4-11 when betting on the total runs Under for -7.95 Units / -48.92% ROI

Mariners Against the Spread (ATS) Record

Against the spread this season, the Mariners are 5-10 against the Run Line (-5 Units / -29.15% ROI).

  • 6-9 when betting on the Moneyline for -6.4 Units / -30.4% ROI
  • 7-8 when betting on the total runs Over for -1.8 Units / -10.94% ROI
  • 8-7 when betting on the total runs Under for +0.25 Units / 1.51% ROI

Astros Keys to the Game vs. the Mariners

The Astros were 56-7 (.889) when they scored 5 or more runs in the 2025 season — 3rd best in MLB; League Avg: .797.

The Astros were 71-4 (.947) when leading entering the 8th inning in the 2025 season — tied for 2nd best in MLB; League Avg: .909.

The Astros are just 1-7 (.125) on the road this season — 2nd lowest in MLB; League Avg: .440.

The Astros are 11-6 (.647) when tied entering the 8th inning since the 2025 season — 5th best in MLB; League Avg: .500.

Mariners Keys to the Game vs. the Astros

The Mariners are just 0-9 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .026.

The Mariners are just 12-27 (.308) vs top 10 scoring offenses since the 2025 season Today, they face the Astros (second in runs scored).

The Mariners were 9-55 (.141) when trailing entering the 8th inning in the 2025 season — 3rd best in MLB; League Avg: .090.

The Mariners were 18-10 (.643) when tied entering the 7th inning in the 2025 season — 4th best in MLB; League Avg: .500.

Astros hitters have an OBP of .523 (65 PA’s) when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Astros hitters have an OPS of .839 (613 PA’s) this season — 2nd best in MLB.

The Astros are batting .404 when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Astros hitters have an OBP of .377 (613 PA’s) this season — best in MLB.

Mariners hitters slugged .712 on the first pitch of at-bats in the 2025 season — best in MLB.

Mariners hitters are slugging just .236 against LHP this season — 2nd lowest in MLB.

Mariners hitters have put just 31% of their swings in play this season — lowest in MLB.

Mariners hitters are slugging .691 on the first pitch of at-bats since the 2025 season — best in MLB.

Astros pitchers have an ERA of 6.47 (129.1 IP) this season — highest in MLB.

Astros pitchers have an ERA of 8.28 (66.1 IP) on the road this season — highest in MLB.

Astros pitchers have an ERA of 9.12 (49.1 IP) over the past seven days (6 games) — highest in MLB.

Astros pitchers have walked 17% of batters over the past seven days (6 games) — highest in MLB.

Mariners pitchers have induced opposing hitters to ground into 18 double plays in 84 opportunities (21%) this season — best in MLB.

Mariners pitchers have walked 7% of batters since the 2025 season — 3rd best in MLB.

Mariners pitchers have walked 6% of batters when facing the leadoff batter in the inning since the 2024 season — best in MLB.

Mariners pitchers have walked 6% of batters this season — 2nd best in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.