• The Mariners are -185 favorites vs the Astros
• Astros vs Mariners Over / Under today: 7.5 Runs
• Astros / Mariners TV Channel: MRTV | SCHN

The Houston Astros (+150) visit T-Mobile Park to take on the Seattle Mariners (-185) on April 13, 2026. First pitch is scheduled for 4:10 pm in Seattle, WA.

This season, the Astros are 6-10 against the spread (ATS), while the Mariners are 6-10 ATS.

Astros vs Mariners Starting Pitchers Today:

• Astros starting pitcher: Michael Burrows 1-2, 5.63 ERA
• Mariners starting pitcher: George Kirby 1-2, 3.60 ERA

Astros vs. Mariners Odds, Run Line, Over/Under & Moneyline

Astros vs Mariners Prediction for Today’s Game

Based on recent trends the model predicts the Mariners will win Monday‘s MLB game with 57.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Astros vs Mariners and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Astros players for Monday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Bets Today:

• Carlos Correa has hit the Runs Over in 16 of his last 25 away games (+11.70 Units / 46% ROI)
• Carlos Correa has hit the Hits Over in 16 of his last 25 away games (+8.90 Units / 23% ROI)
• Cam Smith has hit the Home Runs Over in 2 of his last 10 games (+8.50 Units / 85% ROI)
• Carlos Correa has hit the Total Bases Over in 15 of his last 25 away games (+7.10 Units / 25% ROI)
• Carlos Correa has hit the Hits Runs and RBIs Over in 17 of his last 25 away games (+7.05 Units / 22% ROI)

And here are some favorite MLB player prop bets for Mariners players for Monday‘s game, looking at profitable historical betting trends:

Best Mariners Player Prop Best Bets Today:

• Josh Naylor has hit the Hits Under in 12 of his last 15 games (+14.35 Units / 81% ROI)
• Josh Naylor has hit the Hits Runs and RBIs Under in 13 of his last 15 games (+10.90 Units / 59% ROI)
• Josh Naylor has hit the Total Bases Under in 13 of his last 15 games (+10.80 Units / 46% ROI)
• Luke Raley has hit the Home Runs Over in 2 of his last 7 games at home (+10.50 Units / 150% ROI)
• Cal Raleigh has hit the Singles Under in 17 of his last 20 games (+10.00 Units / 22% ROI)

Astros Best Bets Today:

• The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 14 of their last 20 games (+7.80 Units / 34% ROI)
• The Houston Astros have hit the Game Total Over in 11 of their last 14 games (+7.60 Units / 49% ROI)
• The Houston Astros have hit the Team Total Over in 10 of their last 14 games (+5.05 Units / 29% ROI)
• The Houston Astros have covered the Run Line in 24 of their last 45 away games (+3.45 Units / 6% ROI)

Mariners Best Bets Today:

• The Seattle Mariners have hit the Moneyline in 32 of their last 45 games at home (+14.25 Units / 18% ROI)
• The Seattle Mariners have hit the Team Total Over in 28 of their last 45 games at home (+9.45 Units / 18% ROI)
• The Seattle Mariners have hit the 1st Five Innings (F5) Moneyline in 23 of their last 40 games at home (+8.50 Units / 12% ROI)
• The Seattle Mariners have hit the Game Total Over in 28 of their last 50 games at home (+5.00 Units / 9% ROI)
• The Seattle Mariners have hit the 1st Five Innings (F5) Team Total Over in 29 of their last 50 games at home (+4.50 Units / 7% ROI)

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 7-9 against the Run Line (-1.55 Units / -8.16% ROI).

• 6-10 when betting on the Moneyline for -7.1 Units / -33.73% ROI
• 11-5 when betting on the total runs Over for +5.3 Units / 29.53% ROI
• 5-11 when betting on the total runs Under for -6.95 Units / -40.29% ROI

Mariners Against the Spread (ATS) Record

Against the spread this season, the Mariners are 6-10 against the Run Line (-3.85 Units / -21.21% ROI).

• 7-9 when betting on the Moneyline for -5.4 Units / -23.58% ROI
• 7-9 when betting on the total runs Over for -3 Units / -17% ROI
• 9-7 when betting on the total runs Under for +1.25 Units / 7.12% ROI

Astros Keys to the Game vs. the Mariners

The Astros are just 0-6 (.000) when scoring 4 or fewer runs this season — tied for lowest in MLB; League Avg: .284.

The Astros are just 0-8 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .024.

The Astros were 10-5 (.667) when tied entering the 8th inning in the 2025 season — tied for 3rd best in MLB; League Avg: .500.

The Astros are just 1-8 (.111) on the road this season — 2nd lowest in MLB; League Avg: .446.

Mariners Keys to the Game vs. the Astros

The Mariners are just 0-9 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .097.

The Mariners were 18-10 (.643) when tied entering the 7th inning in the 2025 season — 4th best in MLB; League Avg: .500.

The Mariners were 12-55 (.179) when trailing entering the 7th inning in the 2025 season — 3rd best in MLB; League Avg: .124.

The Mariners are 12-62 (.162) when trailing entering the 7th inning since the 2025 season — 5th best in MLB; League Avg: .124.

Astros Hitting Stats & Trends

The Astros are batting .393 when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Astros hitters have an OBP of .381 (430 PA’s) against RHP this season — best in MLB.

Astros hitters are slugging .821 in lefty-lefty matchups this season — best in MLB.

Astros hitters have an OBP of .514 (70 PA’s) when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Mariners Hitting Stats & Trends

Mariners hitters slugged .712 on the first pitch of at-bats in the 2025 season — best in MLB.

Mariners hitters are slugging just .230 on the road this season — lowest in MLB.

The Mariners are batting just .172 against LHP this season — 3rd lowest in MLB.

Mariners hitters have an OPS of just .490 (223 PA’s) on the road this season — lowest in MLB.

Astros Pitching Stats & Trends

Astros pitchers have walked 15% of batters this season — highest in MLB.

Astros pitchers have an ERA of 8.11 (74.1 IP) on the road this season — highest in MLB.

The Astros have allowed 7.67 runs per game (69/9) on the road this season — highest in MLB.

Astros pitchers have an ERA of 6.49 (137.1 IP) this season — highest in MLB.

Mariners Pitching Stats & Trends

Mariners pitchers have induced opposing hitters to ground into 19 double plays in 87 opportunities (22%) this season — best in MLB.

Mariners pitchers have allowed an OBP of just .269 (3,044 PA’s) when facing the leadoff batter in the inning since the 2024 season — best in MLB.

Mariners pitchers have thrown at least two strikes in their first three pitches to 71% of opposing batters this season — highest in MLB.

Mariners pitchers walked 6% of batters when facing the leadoff batter in the inning in the 2025 season — 3rd best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

Bet now on Astros vs Mariners and all games with BetMGM

Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.