• The Padres are -125 favorites vs the Astros
• Astros vs Padres Over / Under today: 8 Runs
• Astros / Padres TV Channel: PDTV | SCHN

The Houston Astros (+105) visit Petco Park to take on the San Diego Padres (-125) on August 7, 2026. First pitch is scheduled for 9:40 pm in San Diego, CA.

This season, the Astros are 59-57 against the spread (ATS), while the Padres are 61-53 ATS.

Astros vs Padres Starting Pitchers Today:

• Astros starting pitcher: Ronel Blanco 0-1, 7.37 ERA
• Padres starting pitcher: Robbie Ray 10-6, 3.10 ERA

Astros vs. Padres Odds, Run Line, Over/Under & Moneyline

Astros vs Padres Prediction for Today’s Game

Based on recent trends the model predicts the Padres will win Friday‘s MLB game with 53.7% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Astros vs Padres and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Astros players for Friday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Bets Today:

• Taylor Trammell has hit the Home Runs Over in 4 of his last 9 away games (+21.80 Units / 242% ROI)
• Yordan Alvarez has hit the RBIs Under in 20 of his last 25 away games (+11.95 Units / 29% ROI)
• Jeremy Pena has hit the Runs Over in 18 of his last 25 games (+10.95 Units / 40% ROI)
• Yainer Diaz has hit the Total Bases Over in 13 of his last 20 away games (+9.65 Units / 45% ROI)
• Yordan Alvarez has hit the Walks Over in 15 of his last 20 games (+9.30 Units / 37% ROI)

And here are some favorite MLB player prop bets for Padres players for Friday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Best Bets Today:

• Jackson Merrill has hit the RBIs Over in 14 of his last 25 games (+12.80 Units / 51% ROI)
• Ty France has hit the Hits Runs and RBIs Over in 19 of his last 25 games (+12.60 Units / 42% ROI)
• Jake Cronenworth has hit the Walks Under in 14 of his last 15 games at home (+12.10 Units / 41% ROI)
• Ty France has hit the Hits Over in 20 of his last 25 games (+11.55 Units / 22% ROI)
• Luis Campusano has hit the Runs Under in his last 10 games (+10.00 Units / 50% ROI)

Astros Best Bets Today:

• The Houston Astros have hit the Moneyline in 25 of their last 40 away games (+12.00 Units / 29% ROI)
• The Houston Astros have covered the Run Line in 11 of their last 15 games (+10.15 Units / 56% ROI)
• The Houston Astros have hit the Team Total Over in 19 of their last 30 away games (+7.95 Units / 23% ROI)
• The Houston Astros have hit the Game Total Over in 10 of their last 14 away games (+6.70 Units / 43% ROI)
• The Houston Astros have hit the 1st Five Innings (F5) Team Total Under in 16 of their last 25 away games (+4.90 Units / 15% ROI)

Padres Best Bets Today:

• The San Diego Padres have hit the Team Total Over in 30 of their last 50 games (+8.95 Units / 15% ROI)
• The San Diego Padres have hit the Game Total Under in 25 of their last 40 games at home (+8.60 Units / 20% ROI)
• The San Diego Padres have hit the Moneyline in 14 of their last 20 games at home (+6.85 Units / 26% ROI)
• The San Diego Padres have hit the 1st Five Innings (F5) Team Total Over in 12 of their last 18 games at home (+6.40 Units / 32% ROI)
• The San Diego Padres have covered the Run Line in 17 of their last 30 games (+5.50 Units / 15% ROI)

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 59-57 against the Run Line (-2.85 Units / -1.83% ROI).

• 59-57 when betting on the Moneyline for -2.95 Units / -2.19% ROI
• 62-48 when betting on the total runs Over for +8.25 Units / 6.4% ROI
• 48-62 when betting on the total runs Under for -20.05 Units / -15.86% ROI

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 61-53 against the Run Line (+2.3 Units / 1.5% ROI).

• 60-56 when betting on the Moneyline for +0.45 Units / 0.33% ROI
• 53-61 when betting on the total runs Over for -14.15 Units / -11.04% ROI
• 61-53 when betting on the total runs Under for +3.05 Units / 2.4% ROI

Padres vs Astros Home Run Prop Bets Today

Padres vs Astros Total Hits Prop Bets Today

Padres vs Astros Strikeout Prop Bets Today

Astros Keys to the Game vs. the Padres

The Astros were just 0-56 (.000) when trailing entering the 9th inning in the 2024 season — tied for lowest in MLB; League Avg: .050.

The Astros were 10-5 (.667) when tied entering the 8th inning in the 2025 season — tied for 3rd best in MLB; League Avg: .500.

The Astros were 56-7 (.889) when they scored 5 or more runs in the 2025 season — 3rd best in MLB; League Avg: .797.

The Astros were 71-4 (.947) when leading entering the 8th inning in the 2025 season — tied for 2nd best in MLB; League Avg: .909.

Padres Keys to the Game vs. the Astros

The Padres were 66-8 (.892) when they scored 5 or more runs in the 2024 season — 2nd best in MLB; League Avg: .804.

The Padres were 93-69 (.574) in the 2024 season — tied for 4th best in MLB; League Avg: .500.

The Padres were 48-12 (.800) when they had 10 or more hits in the 2025 season — 5th best in MLB; League Avg: .743.

The Padres were 13-8 (.619) when tied entering the 7th inning in the 2024 season — 5th best in MLB; League Avg: .498.

Astros Hitting Stats & Trends

Astros hitters have 37 extra-base hits out of 136 total hits (just 27%) when facing the starting pitcher for the 3rd time in a game this season — 2nd lowest in MLB.

Astros hitters are slugging .416 on the road this season — 5th best in MLB.

Astros hitters are slugging .416 this season — 5th best in MLB.

Astros hitters have 76 extra-base hits out of 174 total hits (44%) on the first pitch of at-bats this season — 2nd best in MLB.

Padres Hitting Stats & Trends

The Padres are batting .379 on the first pitch of at-bats this season — 2nd best in MLB.

Padres hitters are slugging just .355 at home this season — 2nd lowest in MLB.

Padres hitters have an OPS of just .666 (2,059 PA’s) at home this season — 3rd lowest in MLB.

Padres hitters have an OPS of just .672 (1,081 PA’s) against LHP this season — 5th lowest in MLB.

Astros Pitching Stats & Trends

Astros pitchers have walked 12% of batters when facing the leadoff batter in the inning this season — highest in MLB.

Opponents have a groundball rate of just 39% against Astros pitchers this season — 2nd lowest in MLB.

Astros pitchers have walked 11% of batters this season — 2nd highest in MLB.

The Astros have allowed 3.15 runs per game (365/116) in the first 5 innings this season — 2nd highest in MLB.

Padres Pitching Stats & Trends

Padres pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — tied for 4th highest in MLB.

Padres pitchers have allowed an exit velocity over 100 MPH 614 times this season — 5th fewest in MLB.

Opponents have a groundball batting average of .272 against Padres pitchers this season — 2nd highest in MLB.

The Padres have allowed 1.14 runs per game (132/116) in late innings this season — tied for 5th best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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