• The Red Sox are -125 favorites vs the Astros
• Astros vs Red Sox Over / Under today: 9.5 Runs
• Astros / Red Sox TV Channel: SCHN | NSN+

The Houston Astros (+105) visit Fenway Park to take on the Boston Red Sox (-125) on May 1, 2026. First pitch is scheduled for 7:10 pm in Boston, MA.

This season, the Astros are 12-20 against the spread (ATS), while the Red Sox are 10-21 ATS.

Astros vs Red Sox Starting Pitchers Today:

• Astros starting pitcher: Michael Burrows 1-3, 6.26 ERA
• Red Sox starting pitcher: Garrett Crochet 3-3, 6.24 ERA

Astros vs. Red Sox Odds, Run Line, Over/Under & Moneyline

Astros vs Red Sox Prediction for Today’s Game

Based on recent trends the model predicts the Red Sox will win Friday‘s MLB game with 52.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Astros vs Red Sox and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Astros players for Friday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Bets Today:

• Jose Altuve has hit the Runs Under in 16 of his last 20 away games (+10.90 Units / 37% ROI)
• Jose Altuve has hit the Total Bases Under in 19 of his last 25 away games (+10.40 Units / 27% ROI)
• Isaac Paredes has hit the Singles Over in 9 of his last 10 away games (+9.55 Units / 94% ROI)
• Yainer Diaz has hit the Hits Runs and RBIs Over in 17 of his last 25 away games (+8.75 Units / 30% ROI)
• Carlos Correa has hit the Hits Over in 17 of his last 25 away games (+8.60 Units / 19% ROI)

And here are some favorite MLB player prop bets for Red Sox players for Friday‘s game, looking at profitable historical betting trends:

Best Red Sox Player Prop Best Bets Today:

• Carlos Narvaez has hit the Home Runs Over in 2 of his last 4 games (+18.00 Units / 450% ROI)
• Roman Anthony has hit the Runs Under in 19 of his last 25 games (+11.65 Units / 34% ROI)
• Trevor Story has hit the Total Bases Under in 13 of his last 15 games at home (+10.50 Units / 46% ROI)
• Wilyer Abreu has hit the Singles Over in 16 of his last 25 games (+9.35 Units / 37% ROI)
• Jarren Duran has hit the Hits Under in 13 of his last 25 games (+7.15 Units / 27% ROI)

Astros Best Bets Today:

• The Houston Astros have hit the Game Total Over in 23 of their last 30 games (+15.00 Units / 45% ROI)
• The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 23 of their last 35 games (+10.90 Units / 27% ROI)
• The Houston Astros have hit the Team Total Over in 18 of their last 30 games (+4.10 Units / 11% ROI)
• The Houston Astros have hit the 1st Five Innings (F5) Moneyline in 4 of their last 6 away games (+2.60 Units / 43% ROI)
• The Houston Astros have covered the 1st Five Innings (F5) Run Line in 4 of their last 6 away games (+1.30 Units / 17% ROI)

Red Sox Best Bets Today:

• The Boston Red Sox have hit the Team Total Under in 29 of their last 45 games at home (+11.45 Units / 22% ROI)
• The Boston Red Sox have hit the Game Total Under in 28 of their last 45 games at home (+11.35 Units / 23% ROI)
• The Boston Red Sox have hit the 1st Five Innings (F5) Team Total Under in 23 of their last 35 games at home (+8.90 Units / 20% ROI)
• The Boston Red Sox have hit the 1st Five Innings (F5) Moneyline in 4 of their last 7 games (+1.30 Units / 17% ROI)
• The Boston Red Sox have hit the Moneyline in 3 of their last 5 games (+1.15 Units / 22% ROI)

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 12-20 against the Run Line (-10.2 Units / -25.37% ROI).

• 12-20 when betting on the Moneyline for -11.9 Units / -29.53% ROI
• 23-9 when betting on the total runs Over for +12.7 Units / 35.43% ROI
• 9-23 when betting on the total runs Under for -16.1 Units / -46.53% ROI

Red Sox Against the Spread (ATS) Record

Against the spread this season, the Red Sox are 10-21 against the Run Line (-11.6 Units / -31.14% ROI).

• 12-19 when betting on the Moneyline for -11.35 Units / -29.14% ROI
• 16-15 when betting on the total runs Over for -0.65 Units / -1.9% ROI
• 15-16 when betting on the total runs Under for -2.55 Units / -7.49% ROI

Red Sox vs Astros Home Run Prop Bets Today

Red Sox vs Astros Total Hits Prop Bets Today

Red Sox vs Astros Strikeout Prop Bets Today

Astros Keys to the Game vs. the Red Sox

The Astros are just 4-12 (.250) on the road this season — 2nd lowest in MLB; League Avg: .464.

The Astros are just 0-17 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .059.

The Astros are just 0-18 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .112.

The Astros are just 12-20 (.375) this season — tied for 2nd lowest in MLB; League Avg: .500.

Red Sox Keys to the Game vs. the Astros

The Red Sox are just 1-12 (.077) when allowing 10 or more hits this season — tied for 2nd lowest in MLB; League Avg: .241.

The Red Sox are just 0-18 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .059.

The Red Sox are just 0-17 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .112.

The Red Sox are just 5-75 (.062) when trailing entering the 8th inning since the 2025 season — 5th lowest in MLB; League Avg: .094.

Astros Hitting Stats & Trends

The Astros are batting .358 when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Astros hitters have an OBP of .440 (141 PA’s) when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

The Astros are batting .285 on the road this season — 2nd best in MLB.

Astros hitters have an OPS of 1.099 (68 PA’s) in lefty-lefty matchups this season — best in MLB.

Red Sox Hitting Stats & Trends

Red Sox hitters are slugging just .412 in non-two strike counts this season — lowest in MLB.

Red Sox hitters are slugging just .312 at home this season — lowest in MLB.

Red Sox hitters have an OPS of just .603 (465 PA’s) at home this season — lowest in MLB.

Red Sox hitters have an OPS of just .646 (862 PA’s) against RHP this season — 2nd lowest in MLB.

Astros Pitching Stats & Trends

Astros pitchers have walked 14% of batters this season — highest in MLB.

Astros pitchers have an ERA of 6.08 (278.1 IP) this season — highest in MLB.

Astros pitchers have allowed an OBP of .375 (1,271 PA’s) this season — highest in MLB.

The Astros have allowed 3.75 runs per game (120/32) in the first 5 innings this season — highest in MLB.

Red Sox Pitching Stats & Trends

Red Sox pitchers have walked 4% of batters when facing the leadoff batter in the inning this season — best in MLB.

Opponents have a groundball rate of 45% against Red Sox pitchers since the 2025 season — 4th highest in MLB.

Opponents have a groundball batting average of just .196 against Red Sox pitchers this season — best in MLB.

Red Sox pitchers have walked 7% of batters over the past seven days (6 games) — tied for 2nd best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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