Athletics vs Angels Prediction, Odds & Player Prop Bets Today – MLB, May 21

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  • The Athletics are -110 favorites vs the Angels
  • Athletics vs Angels Over / Under today: 8 Runs
  • Athletics / Angels TV Channel: NSCA | ABTV

The Athletics (-110) visit Angel Stadium of Anaheim to take on the Los Angeles Angels (-110) on May 21, 2026. First pitch is scheduled for 9:38 pm in Anaheim, CA.

This season, the Athletics are 25-24 against the spread (ATS), while the Angels are 22-27 ATS.

Athletics vs Angels Starting Pitchers Today:

  • Athletics starting pitcher: , ERA
  • Angels starting pitcher: , ERA

Athletics vs. Angels Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Athletics-1.5 +155O 8 -102-110
Angels +1.5 -190U 8 -118-110

Athletics vs Angels Prediction for Today’s Game

Based on recent trends the model predicts the will win Thursday‘s MLB game with confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Athletics players for Thursday‘s game, looking at profitable historical betting trends:

Best Athletics Player Prop Bets Today:

  • player high – away 

And here are some favorite MLB player prop bets for Angels players for Thursday‘s game, looking at profitable historical betting trends:

Best Angels Player Prop Best Bets Today:

  • player  high – home
  • team high – away
  • team high – home

Athletics Against the Spread (ATS) Record

Against the spread this season, the Athletics are 27-22 against the Run Line (+1.5 Units / 2.26% ROI).

  • 25-24 when betting on the Moneyline for +1.25 Units / 2.26% ROI
  • 23-24 when betting on the total runs Over for -3.25 Units / -6.02% ROI
  • 24-23 when betting on the total runs Under for -1.1 Units / -2.04% ROI

Angels Against the Spread (ATS) Record

Against the spread this season, the Angels are 22-27 against the Run Line (-13 Units / -19.25% ROI).

  • 17-33 when betting on the Moneyline for -12.8 Units / -24.08% ROI
  • 24-25 when betting on the total runs Over for -3.1 Units / -5.63% ROI
  • 25-24 when betting on the total runs Under for -0.95 Units / -1.73% ROI

Angels vs Athletics Home Run Prop Bets Today

Yes
Mike Trout +280
Shea Langeliers +340
Jo Adell +360
Zachary Neto +390
Nick Kurtz +390

Angels vs Athletics Total Hits Prop Bets Today

Over Under
Carlos Cortes 0.5 -225 0.5 +165
Nolan Schanuel 0.5 -220 0.5 +160
Shea Langeliers 0.5 -200 0.5 +150
Zachary Neto 0.5 -190 0.5 +140
Mike Trout 0.5 -185 0.5 +135

Angels vs Athletics Strikeout Prop Bets Today

Over Under
Tyler Soderstrom 0.5 -275 0.5 +190
Jo Adell 0.5 -225 0.5 +165
Josh Lowe 0.5 -220 0.5 +160
Logan O'Hoppe 0.5 -210 0.5 +155
Carlos Cortes 0.5 -200 0.5 +145

Athletics Keys to the Game vs. the Angels

Angels Keys to the Game vs. the Athletics

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.