Athletics vs Astros Prediction, Odds & Player Prop Bets Today – MLB, Aug 22

Houston Astros relief pitcher Steven Okert looks on after earning the save in a 2-1 win in the 12th inning against the Seattle Mariners in a baseball game Tuesday, April 8, 2025, in Seattle. (AP Photo/Lindsey Wasson)
(AP Photo/Lindsey Wasson)
Sportsbook Promos
  • The Astros are -250 favorites vs the Athletics
  • Athletics vs Astros Over / Under today: 8 Runs
  • Athletics / Astros TV Channel: NSCA | SCHN

The Athletics (+200) visit Daikin Park to take on the Houston Astros (-250) on August 22, 2026. First pitch is scheduled for 7:10 pm in Houston, TX.

This season, the Athletics are 49-80 against the spread (ATS), while the Astros are 64-65 ATS.

Athletics vs Astros Starting Pitchers Today:

  • Athletics starting pitcher: , ERA
  • Astros starting pitcher: , ERA

Athletics vs. Astros Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Athletics+1.5 -110O 8 -115+200
Astros -1.5 -110U 8 -105-250

Athletics vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the will win Saturday‘s MLB game with confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Athletics players for Saturday‘s game, looking at profitable historical betting trends:

Best Athletics Player Prop Bets Today:

  • player high – away 

And here are some favorite MLB player prop bets for Astros players for Saturday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

  • player  high – home
  • team high – away
  • team high – home

Athletics Against the Spread (ATS) Record

Against the spread this season, the Athletics are 59-70 against the Run Line (-26.55 Units / -15.32% ROI).

  • 49-80 when betting on the Moneyline for -30 Units / -20.96% ROI
  • 63-61 when betting on the total runs Over for -3.65 Units / -2.57% ROI
  • 61-63 when betting on the total runs Under for -7.85 Units / -5.53% ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 64-65 against the Run Line (-5.25 Units / -3.08% ROI).

  • 65-64 when betting on the Moneyline for -7 Units / -4.56% ROI
  • 67-55 when betting on the total runs Over for +5.65 Units / 3.95% ROI
  • 55-67 when betting on the total runs Under for -18.65 Units / -13.24% ROI

Astros vs Athletics Home Run Prop Bets Today

Yes
Yordan Alvarez +310
Christian Walker +360
Jeremy Pena +375
Cam Smith +390
Isaac Paredes +425

Astros vs Athletics Total Hits Prop Bets Today

Over Under
Yordan Alvarez 0.5 -250 0.5 +180
Isaac Paredes 0.5 -200 0.5 +150
Henry Bolte 0.5 -200 0.5 +150
Jeff McNeil 0.5 -200 0.5 +150
Jose Altuve 0.5 -190 0.5 +140

Astros vs Athletics Strikeout Prop Bets Today

Over Under
Christian Walker 0.5 -275 0.5 +190
Daulton Varsho 0.5 -200 0.5 +145
Cam Smith 0.5 -200 0.5 +150
Jonah Heim 0.5 -200 0.5 +150
Jeremy Pena 0.5 -190 0.5 +140

Athletics Keys to the Game vs. the Astros

Astros Keys to the Game vs. the Athletics

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.