Athletics vs Astros Prediction, Odds & Player Prop Bets Today – MLB, May 21

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MLB betting odds, predictions and betting odds for today's games
(AP Photo)
BetMGM Betting @BETMGM May 21, 2023, 12:02 PM
  • The Astros are -350 favorites vs the Athletics
  • Athletics starting pitcher: James Kaprielian
  • Astros starting pitcher: Framber Valdez
  • Watch the game on SportsNet SW

The Oakland Athletics (+280) visit Minute Maid Park to take on the Houston Astros (-350) on Sunday, May 21, 2023. First pitch is scheduled for 2:10pm EDT in Houston.

The Astros are the betting favorite in this game, with the run line sitting at -2.5 (-110).

The Athletics vs Astros Over/Under is 8.5 total runs for the game.

This season, the Athletics are 10-37 against the spread (ATS), while the Astros are 22-23 ATS.

Athletics vs. Astros Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Athletics+2.5 -110O 8.5 -110+280
Astros -2.5 -110U 8.5 -110-350

Athletics vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Sunday‘s MLB matchup with 51.9% confidence.

This prediction factors in starting pitchers, recent team and player hitting performances, the last 5 games for both the Athletics and Astros and up-to-date player injuries.


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We’ve highlighted some favorite MLB player prop bets for Athletics players for Sunday‘s game, looking at profitable historical betting trends:

Best Athletics Player Prop Bets Today:

  • Esteury Ruiz has hit the Singles Over in 29 of his last 40 games (+17.10 Units / 34% ROI)
  • Esteury Ruiz has hit the Hits Over in 32 of his last 43 games (+15.65 Units / 20% ROI)
  • Jordan Diaz has hit the Hits Runs and RBIs Under in 14 of his last 16 games (+11.85 Units / 51% ROI)
  • Jace Peterson has hit the Singles Over in 11 of his last 15 games (+10.20 Units / 68% ROI)
  • Esteury Ruiz has hit the Total Bases Over in 26 of his last 43 games (+9.85 Units / 18% ROI)

And here are some favorite MLB player prop bets for Astros players for Sunday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

  • Alex Bregman has hit the Total Bases Under in 34 of his last 45 games (+16.60 Units / 21% ROI)
  • Jose Abreu has hit the Total Bases Under in 30 of his last 39 games (+15.20 Units / 23% ROI)
  • Jose Abreu has hit the Runs Under in 32 of his last 42 games (+12.65 Units / 17% ROI)
  • Kyle Tucker has hit the RBIs Over in 22 of his last 44 games (+11.20 Units / 25% ROI)
  • Yordan Alvarez has hit the Hits Over in 13 of his last 15 games (+11.00 Units / 35% ROI)

Astros vs Athletics Home Run Prop Bets Today

Over Under
Nick Allen 0.5 +1400 0.5
Jose Abreu 0.5 +525 0.5 -1200
Kyle Tucker 0.5 +340 0.5 -600
Jordan Diaz 0.5 +900 0.5 -10000
Yordan Alvarez 0.5 +250 0.5 -400

Astros vs Athletics Total Hits Prop Bets Today

Over Under
Nick Allen 0.5 -135 0.5 +105
Jose Abreu 0.5 -250 0.5 +190
Kyle Tucker 0.5 -250 0.5 +180
Jordan Diaz 0.5 -145 0.5 +110
Yordan Alvarez 0.5 -250 0.5 +185

Astros vs Athletics RBI Prop Bets Today

Over Under
Nick Allen 0.5 +375 0.5 -600
Jose Abreu 0.5 +155 0.5 -210
Kyle Tucker 0.5 +140 0.5 -185
Jordan Diaz 0.5 +290 0.5 -400
Yordan Alvarez 0.5 +125 0.5 -160

Astros vs Athletics Strikeout Prop Bets Today

Over Under
Framber Valdez 7.5 +115 7.5 -150
  • The Oakland Athletics have hit the Team Total Under in 22 of their last 33 games (+9.75 Units / 25% ROI)
  • The Oakland Athletics have hit the 1st Five Innings (F5) Team Total Over in 14 of their last 18 away games (+9.65 Units / 43% ROI)
  • The Oakland Athletics have hit the Game Total Over in 15 of their last 22 away games (+7.30 Units / 30% ROI)
  • The Houston Astros have hit the Moneyline in 9 of their last 10 games (+8.20 Units / 49% ROI)
  • The Houston Astros have hit the Game Total Under in 15 of their last 22 games (+7.40 Units / 31% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Team Total Under in 16 of their last 24 games at home (+6.30 Units / 22% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Moneyline in 9 of their last 14 games (+5.85 Units / 29% ROI)
  • The Houston Astros have hit the Team Total Under in 13 of their last 21 games (+3.60 Units / 15% ROI)

Athletics Against the Spread (ATS) Record

Against the spread this MLB season, the Athletics have gone 18-29 against the Run Line (-14.15 Units / -26.23% ROI).

  • 10-37 when betting on the Moneyline for -21.5 Units / -45.6% ROI
  • 27-19 when betting on the total runs Over for +5.7 Units / 10.85% ROI
  • 19-27 when betting on the total runs Under for -10.25 Units / -20.12% ROI

Astros Against the Spread (ATS) Record

Against the spread this MLB season, the Astros have gone 22-23 against the Run Line (-4.1 Units / -6.96% ROI).

  • 26-19 when betting on the Moneyline for -1.3 Units / -1.92% ROI
  • 22-22 when betting on the total runs Over for -2.4 Units / -4.81% ROI
  • 22-22 when betting on the total runs Under for -2 Units / -4.07% ROI

Opponents have a groundball batting average of .611 (11 GB hits out of 18 GBs) against James Kaprielian this season — highest in MLB among starting pitchers with at least 17 total IP; League Avg: .250 — 0 Percentile.

James Kaprielian has an ERA of 10.17 (23.0 IP)this season — 2nd highest in MLB among starting pitchers with at least 17 total IP; League Avg: 4.40 — first Percentile.

Opponents have a groundball rate of just 26% (19/72) against James Kaprielian this season — 8th lowest in MLB among starting pitchers with at least 17 total IP; League Avg: 43% — fourth Percentile.

James Kaprielian has walked 43 of 335 right-handed batters (13%) since last season — highest in MLB among starting pitchers with at least 82 total IP; League Avg: 7% — 0 Percentile.

Astros Starting Pitcher Stats & Trends

Opponents had a groundball rate of 67% (372/555) against Framber Valdez in 2022 — highest among qualified SPs in MLB; League Avg: 44% — 100th Percentile.

Opponents had a groundball rate of 68% (119/174) against Framber Valdez in two-strike counts in 2022 — highest among qualified SPs in MLB; League Avg: 46% — 100th Percentile.

Framber Valdez has thrown inside pitches 48% of the time (511/1,069) with two-strikes since last season — highest among qualified SPs in MLB; League Avg: 31% — 100th Percentile.

Opponents have a groundball rate of 66% (466/706) against Framber Valdez since last season — highest in MLB among starting pitchers with at least 82 total IP; League Avg: 43% — 100th Percentile.

Athletics Keys to the Game vs. the Astros

The Athletics are just 3-5 (.375) when leading entering the 7th inning this season — lowest in MLB; League Avg: .856.

The Athletics are just 58-8 (.879) when leading entering the 9th inning since last season — lowest in MLB; League Avg: .953.

The Athletics are just 2-4 (.333) when leading entering the 8th inning this season — lowest in MLB; League Avg: .896.

The Athletics are just 4-3 (.571) when leading entering the 9th inning this season — lowest in MLB; League Avg: .950.

Astros Keys to the Game vs. the Athletics

The Astros are 22-12 (.647) after a road loss since last season — 2nd best in MLB; League Avg: .448.

The Astros are 51-24 (.680) after a loss since last season — best in MLB; League Avg: .483.

The Astros are 86-7 (.925) when scoring 5 or more runs since last season — best in MLB; League Avg: .802.

The Astros are 14-1 (.933) when they’ve had 10 or more hits this season — 2nd best in MLB; League Avg: .728.

The Athletics have a winning percentage of just 21% this season — lowest in MLB; League Avg: 50%.

The Athletics have a winning percentage of just 20% at home this season — lowest in MLB; League Avg: 53%.

Athletics hitters have an OBP of just .284 (5,635 PA’s) against RHP since last season — 2nd lowest in MLB; League Avg: .312.

Athletics hitters have an OPS of just .630 (5,635 PA’s) against RHP since last season — 2nd lowest in MLB; League Avg: .707.

Astros hitters have just 406 strikeouts in 2,332 PA’s (17%) against LHP since last season — best in MLB; League Avg: 22%.

Astros hitters have just 786 strikeouts in 4,413 PA’s (18%) against LHP since the 2021 season — best in MLB; League Avg: 23%.

Astros hitters have just 85 strikeouts in 482 PA’s (18%) against LHP this season — 2nd best in MLB; League Avg: 22%.

Astros hitters struck out just 321 times in 1,850 PA’s (17%) against LHP in 2022 — best in MLB; League Avg: 22%.

Opponents have a groundball rate of just 38% against Athletics pitchers this season — lowest in MLB; League Avg: 43%.

Athletics pitchers have walked 228 of 1,939 batters (12%) this season — highest in MLB; League Avg: 9%.

The Athletics have allowed 7.91 runs per game (174/22) on the road this season — highest in MLB; League Avg: 4.61.

The Athletics have allowed 7.28 runs per game (342/47) this season — highest in MLB; League Avg: 4.58.

Astros pitchers have allowed opponents to score in three different innings in 28% of their games since last season — lowest in MLB; League Avg: 44%.

Astros pitchers have an ERA of 3.10 (894.0 IP) on the road since last season — best in MLB; League Avg: 4.20.

Astros pitchers have a strikeout rate of 47% with two-strikes this season — best in MLB; League Avg: 43%.

Opponents have a miss rate of 28% against Astros pitchers since last season — 2nd best in MLB; League Avg: 26%.

Astros vs. Athletics Injuries Tonight That May Affect Prop Bets 

  • Lance McCullers Jr. (Astros): Elbow, D15
  • Luis Garcia (Astros): Elbow, D15
  • Michael Brantley (Astros): Shoulder, D10
  • José Urquidy (Astros): Shoulder, D15
  • Parker Mushinski (Astros): Spine, D15
  • Trevor May (Athletics): Personal, D15
  • Dany Jiménez (Athletics): Shoulder, D60
  • Kenneth Waldichuk (Athletics): Calf, Day-to-Day
  • Kirby Snead (Athletics): Shoulder, D60
  • Manuel Piña (Athletics): Wrist, D60
  • Mason Miller (Athletics): Elbow, D15
  • Drew Rucinski (Athletics): Illness, D15
  • Zachary Jackson (Athletics): Undisclosed, D15
  • Seth Brown (Athletics): Oblique, D10
  • Paul Blackburn (Athletics): Finger, D15
  • Frederic Tarnok (Athletics): Undisclosed, D60

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.