Athletics vs Mariners Prediction, Odds & Player Prop Bets Today – MLB, Apr 21

Seattle Mariners' Julio Rodriguez reacts after the umpires confirmed a challenged call, ruling him out for fan interference on a foul ball during the eighth inning of the team's baseball game against the Oakland Athletics, Tuesday, May 23, 2023, in Seattle.
(AP Photo/Caean Couto)
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  • The Mariners are -185 favorites vs the Athletics
  • Athletics vs Mariners Over / Under today: 7.5 Runs
  • Athletics / Mariners TV Channel: MRTV | NSCA

The Athletics (+150) visit T-Mobile Park to take on the Seattle Mariners (-185) on April 21, 2026. First pitch is scheduled for 9:40 pm in Seattle, WA.

This season, the Athletics are 12-11 against the spread (ATS), while the Mariners are 9-15 ATS.

Athletics vs Mariners Starting Pitchers Today:

  • Athletics starting pitcher: , ERA
  • Mariners starting pitcher: , ERA

Athletics vs. Mariners Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Athletics+1.5 -150O 7.5 -110+150
Mariners -1.5 +125U 7.5 -110-185

Athletics vs Mariners Prediction for Today’s Game

Based on recent trends the model predicts the will win Tuesday‘s MLB game with confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Athletics players for Tuesday‘s game, looking at profitable historical betting trends:

Best Athletics Player Prop Bets Today:

  • player high – away 

And here are some favorite MLB player prop bets for Mariners players for Tuesday‘s game, looking at profitable historical betting trends:

Best Mariners Player Prop Best Bets Today:

  • player  high – home
  • team high – away
  • team high – home

Athletics Against the Spread (ATS) Record

Against the spread this season, the Athletics are 13-10 against the Run Line (-0.45 Units / -1.38% ROI).

  • 12-11 when betting on the Moneyline for +2.85 Units / 11.31% ROI
  • 12-10 when betting on the total runs Over for +1 Units / 3.94% ROI
  • 10-12 when betting on the total runs Under for -3.1 Units / -12.3% ROI

Mariners Against the Spread (ATS) Record

Against the spread this season, the Mariners are 9-15 against the Run Line (-4.45 Units / -17.02% ROI).

  • 10-14 when betting on the Moneyline for -8.65 Units / -25.67% ROI
  • 11-13 when betting on the total runs Over for -3.2 Units / -12.14% ROI
  • 13-11 when betting on the total runs Under for +0.95 Units / 3.58% ROI

Mariners vs Athletics Home Run Prop Bets Today

Yes
Cal Raleigh +350
Nick Kurtz +360
Shea Langeliers +375
Julio Rodriguez +380
Randy Arozarena +450

Mariners vs Athletics Total Hits Prop Bets Today

Over Under
Jacob Wilson 0.5 -225 0.5 +165
Jeff McNeil 0.5 -200 0.5 +150
Julio Rodriguez 0.5 -190 0.5 +140
Carlos Cortes 0.5 -175 0.5 +130
Shea Langeliers 0.5 -175 0.5 +130

Mariners vs Athletics Strikeout Prop Bets Today

Over Under
Julio Rodriguez 0.5 -275 0.5 +195
Randy Arozarena 0.5 -235 0.5 +170
Lawrence Butler 0.5 -225 0.5 +165
Tyler Soderstrom 0.5 -210 0.5 +155
Rob Refsnyder 0.5 -200 0.5 +145

Athletics Keys to the Game vs. the Mariners

Mariners Keys to the Game vs. the Athletics

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.