Blue Jays vs Angels Prediction, Odds & Player Prop Bets Today – MLB, Apr 21

Los Angeles Angels starting pitcher Josรฉ Soriano throws in the first inning of a baseball game against the Cincinnati Reds, Sunday, April 21, 2024, in Cincinnati.
(AP Photo/Carolyn Kaster)
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  • The Blue Jays are +100 favorites vs the Angels
  • Blue Jays vs Angels Over / Under today: 9.5 Runs
  • Blue Jays / Angels TV Channel: FDW | RSN1 | ESUN

The Toronto Blue Jays (+100) visit Angel Stadium of Anaheim to take on the Los Angeles Angels (-120) on April 21, 2026. First pitch is scheduled for 9:38 pm in Anaheim, CA.

This season, the Blue Jays are 9-13 against the spread (ATS), while the Angels are 14-10 ATS.

Blue Jays vs Angels Starting Pitchers Today:

  • Blue Jays starting pitcher: Patrick Corbin 0-0, 4.66 ERA
  • Angels starting pitcher: Jack Kochanowicz 2-0, 3.47 ERA

Blue Jays vs. Angels Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Blue Jays-1.5 +155O 9.5 -110+100
Angels +1.5 -190U 9.5 -110-120

Blue Jays vs Angels Prediction for Today’s Game

Based on recent trends the model predicts the Angels will win Tuesday‘s MLB game with 51.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Blue Jays players for Tuesday‘s game, looking at profitable historical betting trends:

Best Blue Jays Player Prop Bets Today:

  • Vladimir Guerrero Jr has hit the Singles Over in 17 of his last 20 away games (+13.60 Units / 52% ROI)
  • Ernie Clement has hit the Hits Over in 19 of his last 25 games (+11.55 Units / 25% ROI)
  • Andres Gimenez has hit the Home Runs Over in 2 of his last 9 away games (+11.50 Units / 128% ROI)
  • Vladimir Guerrero Jr has hit the RBIs Over in 12 of his last 20 away games (+10.90 Units / 55% ROI)
  • Ernie Clement has hit the Total Bases Over in 15 of his last 25 away games (+9.05 Units / 30% ROI)

And here are some favorite MLB player prop bets for Angels players for Tuesday‘s game, looking at profitable historical betting trends:

Best Angels Player Prop Best Bets Today:

  • Oswald Peraza has hit the Home Runs Over in 3 of his last 6 games (+20.00 Units / 333% ROI)
  • Jo Adell has hit the Singles Over in 17 of his last 25 games (+13.65 Units / 55% ROI)
  • Jack Kochanowicz has hit the Walks Allowed Over in 16 of his last 20 games (+12.05 Units / 44% ROI)
  • Mike Trout has hit the Runs Over in 17 of his last 25 games (+9.60 Units / 36% ROI)
  • Mike Trout has hit the RBIs Under in his last 9 games at home (+9.00 Units / 46% ROI)
  • The Toronto Blue Jays have hit the 1st Five Innings (F5) Team Total Under in 17 of their last 22 games (+12.30 Units / 46% ROI)
  • The Toronto Blue Jays have hit the Game Total Over in 26 of their last 45 away games (+7.50 Units / 15% ROI)
  • The Toronto Blue Jays have hit the Team Total Over in 26 of their last 45 games (+4.95 Units / 10% ROI)
  • The Toronto Blue Jays have hit the 1st Five Innings (F5) Moneyline in 21 of their last 45 games (+3.00 Units / 5% ROI)
  • The Toronto Blue Jays have covered the 1st Five Innings (F5) Run Line in 25 of their last 45 games (+2.30 Units / 4% ROI)
  • The Los Angeles Angels have hit the Team Total Under in 30 of their last 45 games at home (+12.70 Units / 24% ROI)
  • The Los Angeles Angels have hit the 1st Five Innings (F5) Team Total Over in 13 of their last 15 games (+11.60 Units / 65% ROI)
  • The Los Angeles Angels have covered the 1st Five Innings (F5) Run Line in 16 of their last 24 games (+6.45 Units / 23% ROI)
  • The Los Angeles Angels have covered the Run Line in 7 of their last 9 games (+4.95 Units / 43% ROI)
  • The Los Angeles Angels have hit the 1st Five Innings (F5) Moneyline in 10 of their last 23 games (+4.30 Units / 17% ROI)

Blue Jays Against the Spread (ATS) Record

Against the spread this season, the Blue Jays are 7-15 against the Run Line (-9.25 Units / -34.97% ROI).

  • 9-13 when betting on the Moneyline for -10.1 Units / -30.56% ROI
  • 11-11 when betting on the total runs Over for -1.15 Units / -4.73% ROI
  • 11-11 when betting on the total runs Under for -1.05 Units / -4.36% ROI

Angels Against the Spread (ATS) Record

Against the spread this season, the Angels are 14-10 against the Run Line (-0.3 Units / -0.9% ROI).

  • 11-13 when betting on the Moneyline for +2.8 Units / 11.38% ROI
  • 12-11 when betting on the total runs Over for +0 Units / 0% ROI
  • 11-12 when betting on the total runs Under for -1.85 Units / -7.09% ROI

Angels vs Blue Jays Home Run Prop Bets Today

Yes
Jo Adell +280
Zachary Neto +333
Daulton Varsho +333
Mike Trout +350
Jorge Soler +390

Angels vs Blue Jays Total Hits Prop Bets Today

Over Under
Eloy Jimenez 0.5 -250 0.5 +180
Jo Adell 0.5 -235 0.5 +170
Ernie Clement 0.5 -235 0.5 +175
Zachary Neto 0.5 -235 0.5 +175
Vaughn Grissom 0.5 -225 0.5 +165

Angels vs Blue Jays Strikeout Prop Bets Today

Over Under
Zachary Neto 0.5 -250 0.5 +180
Bryce Teodosio 0.5 -200 0.5 +150
Logan O'Hoppe 0.5 -190 0.5 +140
Daulton Varsho 0.5 -190 0.5 +140
Jo Adell 0.5 -190 0.5 +140

Blue Jays Keys to the Game vs. the Angels

The Blue Jays were 12-53 (.185) when trailing entering the 8th inning in the 2025 season — best in MLB; League Avg: .090.

The Blue Jays are 14-63 (.182) when trailing entering the 8th inning since the 2025 season — best in MLB; League Avg: .092.

The Blue Jays are 78-5 (.940) when scoring 5 or more runs since the 2025 season — best in MLB; League Avg: .793.

The Blue Jays are 2-11 (.154) when trailing entering the 9th inning this season — 3rd best in MLB; League Avg: .052.

Angels Keys to the Game vs. the Blue Jays

The Angels are just 45-67 (.402) vs the bottom 10 runs allowed teams since the 2024 season Today, they face the Blue Jays (25th runs allowed).

The Angels are just 0-10 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .052.

The Angels were just 43-8 (.843) when leading entering the 7th inning in the 2025 season — 5th lowest in MLB; League Avg: .875.

The Angels were 19-6 (.760) when tied entering the 7th inning in the 2025 season — best in MLB; League Avg: .500.

Blue Jays hitters have struck out in just 18% of their PA’s against LHP since the 2025 season — best in MLB.

Blue Jays hitters have struck out in just 13% of their PA’s against LHP this season — best in MLB.

Blue Jays hitters have struck out in just 18% of their PA’s against RHP since the 2025 season — best in MLB.

Blue Jays hitters struck out in just 18% of their PA’s in the 2025 season — best in MLB.

Angels hitters have struck out in 27% of their PA’s against RHP since the 2025 season — highest in MLB.

Angels hitters struck out in 27% of their PA’s against RHP in the 2025 season — highest in MLB.

The Angels batted just .116 on pitches out of the zone in the 2025 season — lowest in MLB.

The Angels batted just .140 with two-strikes in the 2025 season — lowest in MLB.

Blue Jays pitchers won 45% of games in which they allowed their opponent to score in three different innings in the 2025 season — highest in MLB.

Blue Jays pitchers have a strikeout rate of 27% this season — best in MLB.

Opponents have a miss rate of 28% against Blue Jays pitchers this season — 5th best in MLB.

Blue Jays pitchers have a strikeout rate of 32% versus the bottom of the order this season — best in MLB.

Angels pitchers have walked 10% of batters since the 2025 season — highest in MLB.

Angels pitchers have walked 11% of batters when facing the leadoff batter in the inning since the 2025 season — highest in MLB.

Angels pitchers walked 11% of batters when facing the leadoff batter in the inning in the 2025 season — highest in MLB.

Angels pitchers have walked 10% of batters when facing the leadoff batter in the inning since the 2024 season — highest in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.