• The Angels are -155 favorites vs the Blue Jays
• Blue Jays vs Angels Over / Under today: 8 Runs
• Blue Jays / Angels TV Channel: FDW | RSN

The Toronto Blue Jays (+130) visit Angel Stadium of Anaheim to take on the Los Angeles Angels (-155) on April 22, 2026. First pitch is scheduled for 3:07 pm in Anaheim, CA.

This season, the Blue Jays are 10-13 against the spread (ATS), while the Angels are 14-11 ATS.

Blue Jays vs Angels Starting Pitchers Today:

• Blue Jays starting pitcher: Eric Lauer 1-3, 7.14 ERA
• Angels starting pitcher: Jose Soriano 5-0, 0.28 ERA

Blue Jays vs. Angels Odds, Run Line, Over/Under & Moneyline

Blue Jays vs Angels Prediction for Today’s Game

Based on recent trends the model predicts the Angels will win Wednesday‘s MLB game with 57.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Blue Jays players for Wednesday‘s game, looking at profitable historical betting trends:

Best Blue Jays Player Prop Bets Today:

• Vladimir Guerrero Jr has hit the Singles Over in 17 of his last 20 away games (+13.60 Units / 52% ROI)
• Ernie Clement has hit the Hits Over in 19 of his last 25 games (+12.20 Units / 27% ROI)
• Vladimir Guerrero Jr has hit the RBIs Over in 12 of his last 20 away games (+10.90 Units / 55% ROI)
• Andres Gimenez has hit the Home Runs Over in 2 of his last 10 away games (+10.50 Units / 105% ROI)
• Nathan Lukes has hit the Hits Runs and RBIs Under in 15 of his last 20 games (+9.65 Units / 37% ROI)

And here are some favorite MLB player prop bets for Angels players for Wednesday‘s game, looking at profitable historical betting trends:

Best Angels Player Prop Best Bets Today:

• Oswald Peraza has hit the Home Runs Over in 3 of his last 7 games (+19.00 Units / 271% ROI)
• Jo Adell has hit the Singles Over in 16 of his last 25 games (+11.15 Units / 44% ROI)
• Mike Trout has hit the RBIs Under in his last 10 games at home (+10.00 Units / 46% ROI)
• Mike Trout has hit the Runs Over in 17 of his last 25 games (+9.60 Units / 35% ROI)
• Bryce Teodosio has hit the Total Bases Under in 15 of his last 20 games (+9.50 Units / 37% ROI)

Blue Jays Best Bets Today:

• The Toronto Blue Jays have hit the 1st Five Innings (F5) Team Total Under in 18 of their last 23 games (+13.30 Units / 47% ROI)
• The Toronto Blue Jays have hit the Game Total Over in 28 of their last 50 away games (+7.35 Units / 13% ROI)
• The Toronto Blue Jays have hit the Team Total Under in 12 of their last 18 games (+5.55 Units / 26% ROI)
• The Toronto Blue Jays have hit the 1st Five Innings (F5) Moneyline in 21 of their last 45 games (+3.00 Units / 5% ROI)
• The Toronto Blue Jays have covered the 1st Five Innings (F5) Run Line in 25 of their last 45 games (+2.30 Units / 4% ROI)

Angels Best Bets Today:

• The Los Angeles Angels have hit the Team Total Under in 22 of their last 30 games at home (+13.05 Units / 37% ROI)
• The Los Angeles Angels have hit the 1st Five Innings (F5) Team Total Over in 13 of their last 16 games (+10.50 Units / 55% ROI)
• The Los Angeles Angels have covered the 1st Five Innings (F5) Run Line in 17 of their last 25 games (+7.50 Units / 25% ROI)
• The Los Angeles Angels have hit the 1st Five Innings (F5) Moneyline in 11 of their last 24 games (+5.30 Units / 20% ROI)
• The Los Angeles Angels have hit the Game Total Under in 6 of their last 8 games (+4.90 Units / 55% ROI)

Blue Jays Against the Spread (ATS) Record

Against the spread this season, the Blue Jays are 8-15 against the Run Line (-8 Units / -29.14% ROI).

• 10-13 when betting on the Moneyline for -9.1 Units / -26.65% ROI
• 11-12 when betting on the total runs Over for -2.2 Units / -8.68% ROI
• 12-11 when betting on the total runs Under for -0.05 Units / -0.2% ROI

Angels Against the Spread (ATS) Record

Against the spread this season, the Angels are 14-11 against the Run Line (-1.8 Units / -5.18% ROI).

• 11-14 when betting on the Moneyline for +1.7 Units / 6.61% ROI
• 12-12 when betting on the total runs Over for -1.05 Units / -3.78% ROI
• 12-12 when betting on the total runs Under for -0.85 Units / -3.12% ROI

Angels vs Blue Jays Home Run Prop Bets Today

Angels vs Blue Jays Total Hits Prop Bets Today

Angels vs Blue Jays Strikeout Prop Bets Today

Blue Jays Keys to the Game vs. the Angels

The Blue Jays are 2-11 (.154) when trailing entering the 9th inning this season — 3rd best in MLB; League Avg: .050.

The Blue Jays are 78-5 (.940) when scoring 5 or more runs since the 2025 season — best in MLB; League Avg: .793.

The Blue Jays are 14-63 (.182) when trailing entering the 8th inning since the 2025 season — best in MLB; League Avg: .092.

The Blue Jays were 12-53 (.185) when trailing entering the 8th inning in the 2025 season — best in MLB; League Avg: .090.

Angels Keys to the Game vs. the Blue Jays

The Angels are just 45-68 (.398) vs the bottom 10 runs allowed teams since the 2024 season Today, they face the Blue Jays (24th runs allowed).

The Angels are just 0-9 (.000) when trailing entering the 7th inning this season — tied for lowest in MLB; League Avg: .134.

The Angels are just 24-29 (.453) vs the bottom 10 runs allowed teams since the 2025 season Today, they face the Blue Jays (24th runs allowed).

The Angels were 19-6 (.760) when tied entering the 7th inning in the 2025 season — best in MLB; League Avg: .500.

Blue Jays Hitting Stats & Trends

Blue Jays hitters have struck out in just 13% of their PA’s against LHP this season — best in MLB.

Blue Jays hitters struck out in just 18% of their PA’s in the 2025 season — best in MLB.

Blue Jays hitters have struck out in just 18% of their PA’s against LHP since the 2025 season — best in MLB.

Blue Jays hitters struck out in just 17% of their PA’s against RHP in the 2025 season — 2nd best in MLB.

Angels Hitting Stats & Trends

Angels hitters struck out in 27% of their PA’s against RHP in the 2025 season — highest in MLB.

Angels hitters struck out in 27% of their PA’s in the 2025 season — highest in MLB.

Angels hitters have struck out in 27% of their PA’s against RHP since the 2025 season — highest in MLB.

Angels hitters have struck out in 27% of their PA’s since the 2025 season — highest in MLB.

Blue Jays Pitching Stats & Trends

Blue Jays pitchers have a strikeout rate of 27% this season — best in MLB.

Blue Jays pitchers won 45% of games in which they allowed their opponent to score in three different innings in the 2025 season — highest in MLB.

Opponents have a miss rate of 28% against Blue Jays pitchers this season — 5th best in MLB.

Blue Jays pitchers have a strikeout rate of 47% with two-strikes this season — best in MLB.

Angels Pitching Stats & Trends

Angels pitchers walked 11% of batters when facing the leadoff batter in the inning in the 2025 season — highest in MLB.

Angels pitchers have walked 11% of batters when facing the leadoff batter in the inning since the 2025 season — highest in MLB.

Angels pitchers have walked 10% of batters since the 2025 season — highest in MLB.

Angels pitchers have walked 10% of batters when facing the leadoff batter in the inning since the 2024 season — highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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