Blue Jays vs Cubs Prediction, Odds & Player Prop Bets Today – MLB, Jun 21

Chicago Cubs' Dansby Swanson waves to the crowd before batting against his former team the Atlanta Braves in the second inning of a baseball game, Tuesday, Sept. 26, 2023, in Atlanta.
(AP Photo/John Bazemore)
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  • The Blue Jays are -120 favorites vs the Cubs
  • Blue Jays vs Cubs Over / Under today: 7 Runs
  • Blue Jays / Cubs TV Channel: MARQ | RSN | TVA

The Toronto Blue Jays (-120) visit Wrigley Field to take on the Chicago Cubs (+100) on June 21, 2026. First pitch is scheduled for 2:20 pm in Chicago, IL.

This season, the Blue Jays are 38-39 against the spread (ATS), while the Cubs are 29-48 ATS.

Blue Jays vs Cubs Starting Pitchers Today:

  • Blue Jays starting pitcher: Dylan Cease 4-3, 2.71 ERA
  • Cubs starting pitcher: Shota Imanaga 4-6, 4.26 ERA

Blue Jays vs. Cubs Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Blue Jays-1.5 +150O 7 -110-120
Cubs +1.5 -185U 7 -110+100

Blue Jays vs Cubs Prediction for Today’s Game

Based on recent trends the model predicts the Blue Jays will win Sunday‘s MLB game with 53.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Blue Jays players for Sunday‘s game, looking at profitable historical betting trends:

Best Blue Jays Player Prop Bets Today:

  • Jesus Sanchez has hit the Runs Under in 22 of his last 25 away games (+15.80 Units / 32% ROI)
  • Andres Gimenez has hit the Home Runs Over in 2 of his last 10 away games (+12.50 Units / 125% ROI)
  • Kazuma Okamoto has hit the Total Bases Over in 14 of his last 20 games (+9.10 Units / 37% ROI)
  • Ernie Clement has hit the Hits Over in 18 of his last 25 games (+8.95 Units / 18% ROI)
  • Davis Schneider has hit the Hits Runs and RBIs Under in 17 of his last 25 games (+8.75 Units / 30% ROI)

And here are some favorite MLB player prop bets for Cubs players for Sunday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Best Bets Today:

  • Pete Crow-Armstrong has hit the Home Runs Over in 7 of his last 10 games at home (+23.50 Units / 235% ROI)
  • Nico Hoerner has hit the Hits Under in 19 of his last 25 games at home (+15.10 Units / 34% ROI)
  • Pete Crow-Armstrong has hit the Total Bases Over in 16 of his last 20 games (+14.00 Units / 65% ROI)
  • Nico Hoerner has hit the Hits Runs and RBIs Under in 19 of his last 25 games (+13.20 Units / 47% ROI)
  • Michael Busch has hit the Runs Under in 17 of his last 20 games at home (+12.65 Units / 41% ROI)
  • The Toronto Blue Jays have covered the Run Line in 24 of their last 40 games (+8.05 Units / 15% ROI)
  • The Toronto Blue Jays have hit the 1st Five Innings (F5) Team Total Under in 24 of their last 40 away games (+6.85 Units / 14% ROI)
  • The Toronto Blue Jays have hit the Team Total Under in 24 of their last 40 away games (+6.25 Units / 13% ROI)
  • The Toronto Blue Jays have hit the Moneyline in 9 of their last 14 away games (+6.00 Units / 41% ROI)
  • The Toronto Blue Jays have hit the Game Total Over in 13 of their last 20 games (+5.40 Units / 25% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Under in 29 of their last 45 games (+12.10 Units / 23% ROI)
  • The Chicago Cubs have hit the Team Total Under in 12 of their last 17 games at home (+6.55 Units / 33% ROI)
  • The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 8 of their last 10 games (+5.80 Units / 48% ROI)
  • The Chicago Cubs have hit the Game Total Under in 26 of their last 45 games (+5.60 Units / 11% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 8 of their last 10 games (+5.20 Units / 34% ROI)

Blue Jays Against the Spread (ATS) Record

Against the spread this season, the Blue Jays are 39-37 against the Run Line (-1.3 Units / -1.29% ROI).

  • 38-39 when betting on the Moneyline for -7.95 Units / -8.15% ROI
  • 38-36 when betting on the total runs Over for -1.35 Units / -1.6% ROI
  • 36-38 when betting on the total runs Under for -5.6 Units / -6.6% ROI

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 29-48 against the Run Line (-20.45 Units / -22.61% ROI).

  • 40-37 when betting on the Moneyline for -7.7 Units / -7.25% ROI
  • 40-36 when betting on the total runs Over for +0.95 Units / 1.12% ROI
  • 36-40 when betting on the total runs Under for -7.45 Units / -8.8% ROI

Cubs vs Blue Jays Home Run Prop Bets Today

Yes
Kazuma Okamoto +360
Vladimir Guerrero Jr. +525
George Springer +525
Pete Crow-Armstrong +525
Davis Schneider +550

Cubs vs Blue Jays Total Hits Prop Bets Today

Over Under
Vladimir Guerrero Jr. 0.5 -250 0.5 +185
George Springer 0.5 -210 0.5 +155
Alejandro Kirk 0.5 -210 0.5 +155
Pete Crow-Armstrong 0.5 -185 0.5 +135
Kazuma Okamoto 0.5 -185 0.5 +135

Cubs vs Blue Jays Strikeout Prop Bets Today

Over Under
Alex Bregman 0.5 -235 0.5 +175
George Springer 0.5 -235 0.5 +170
Carson Kelly 0.5 -210 0.5 +155
Moises Ballesteros 0.5 -200 0.5 +145
Yohendrick Pinango 0.5 -185 0.5 +135

Blue Jays Keys to the Game vs. the Cubs

The Blue Jays are 6-30 (.167) when trailing entering the 8th inning this season — 3rd best in MLB; League Avg: .104.

The Blue Jays are 18-83 (.178) when trailing entering the 8th inning since the 2025 season — best in MLB; League Avg: .095.

The Blue Jays are 21-80 (.208) when trailing entering the 7th inning since the 2025 season — 2nd best in MLB; League Avg: .129.

The Blue Jays are 42-3 (.933) when they’ve had 5 or more XBH since the 2025 season — best in MLB; League Avg: .795.

Cubs Keys to the Game vs. the Blue Jays

The Cubs are 12-4 (.750) when they’ve scored in the first inning this season — 3rd best in MLB; League Avg: .645.

The Cubs are 4-35 (.103) when trailing entering the 9th inning this season — 5th best in MLB; League Avg: .055.

The Cubs are just 7-30 (.189) when scoring 4 or fewer runs this season — 3rd lowest in MLB; League Avg: .272.

The Cubs are just 4-14 (.222) when their opponents score in the first inning this season — 2nd lowest in MLB; League Avg: .355.

Blue Jays hitters have struck out in just 19% of their PA’s against RHP this season — best in MLB.

Blue Jays hitters are slugging just .478 on the first pitch of at-bats this season — 3rd lowest in MLB.

Blue Jays hitters have chased 34% of pitches out of the zone against RHP this season — highest in MLB.

The Blue Jays are batting .192 with two-strikes this season — best in MLB.

Cubs hitters have an OPS of .765 (843 PA’s) against LHP this season — 3rd best in MLB.

The Cubs are batting .259 against LHP this season — tied for 4th best in MLB.

Cubs hitters have an OBP of .352 (843 PA’s) against LHP this season — 2nd best in MLB.

Cubs hitters have an OBP of .351 (299 PA’s) when facing the starting pitcher for the 3rd time in a game this season — 5th best in MLB.

Blue Jays pitchers have allowed an average Exit Velocity of 87.7 MPH (1,866 batted balls) this season — 2nd best in MLB.

The Blue Jays pitchers have allowed an average Exit Velocity of just 87.7 MPH this season (1,866 balls in play) — 2nd best in MLB

Opponents have a groundball batting average of just .229 against Blue Jays pitchers with runners on base this season — 3rd best in MLB.

Blue Jays pitchers have a strikeout rate of 27% versus the bottom of the order this season — 4th best in MLB.

Opponents have a groundball batting average of just .208 against Cubs pitchers with runners on base this season — best in MLB.

Cubs pitchers have picked-off 13 runners from first base this season — most in MLB.

Cubs pitchers have picked-off 13 runners this season — most in MLB.

The Cubs pitchers have allowed an average Exit Velocity of 89.6 MPH this season (1,939 balls in play) — 4th highest in MLB

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.