Braves vs Nationals Prediction, Odds & Player Prop Bets Today – MLB, Apr 22

Washington Nationals' Luis Garcia hits an RBI single against the Seattle Mariners to score CJ Abrams during the third inning of a baseball game Monday, June 26, 2023, in Seattle.
(AP Photo/Lindsey Wasson)
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  • The Braves are -140 favorites vs the Nationals
  • Braves vs Nationals Over / Under today: 9 Runs
  • Braves / Nationals TV Channel: BRVN | NATV

The Atlanta Braves (-140) visit Nationals Park to take on the Washington Nationals (+115) on April 22, 2026. First pitch is scheduled for 6:45 pm in Washington, D.C., DC.

This season, the Braves are 16-8 against the spread (ATS), while the Nationals are 14-9 ATS.

Braves vs Nationals Starting Pitchers Today:

  • Braves starting pitcher: Martin Perez 1-1, 2.22 ERA
  • Nationals starting pitcher: Zack Littell 0-2, 7.11 ERA

Braves vs. Nationals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Braves-1.5 +120O 9 -115-140
Nationals +1.5 -145U 9 -105+115

Braves vs Nationals Prediction for Today’s Game

Based on recent trends the model predicts the Braves will win Wednesday‘s MLB game with 60.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Braves players for Wednesday‘s game, looking at profitable historical betting trends:

Best Braves Player Prop Bets Today:

  • Ozzie Albies has hit the RBIs Over in 15 of his last 25 away games (+15.50 Units / 62% ROI)
  • Dominic Smith has hit the Total Bases Over in 20 of his last 25 games (+15.05 Units / 41% ROI)
  • Michael Harris II has hit the Home Runs Over in 3 of his last 8 games (+14.50 Units / 181% ROI)
  • Drake Baldwin has hit the Runs Over in 19 of his last 25 games (+14.30 Units / 56% ROI)
  • Matt Olson has hit the Hits Over in 21 of his last 25 games (+12.70 Units / 25% ROI)

And here are some favorite MLB player prop bets for Nationals players for Wednesday‘s game, looking at profitable historical betting trends:

Best Nationals Player Prop Best Bets Today:

  • James Wood has hit the Home Runs Over in 6 of his last 9 games at home (+27.10 Units / 301% ROI)
  • Daylen Lile has hit the Hits Over in 19 of his last 25 games (+10.40 Units / 21% ROI)
  • James Wood has hit the Singles Under in 19 of his last 25 games (+10.00 Units / 26% ROI)
  • Jacob Young has hit the Hits Runs and RBIs Over in 14 of his last 20 games (+9.20 Units / 37% ROI)
  • Jacob Young has hit the Total Bases Over in 12 of his last 15 games at home (+8.45 Units / 39% ROI)
  • The Atlanta Braves have covered the Run Line in 31 of their last 40 away games (+25.15 Units / 50% ROI)
  • The Atlanta Braves have hit the Moneyline in 26 of their last 40 away games (+13.45 Units / 29% ROI)
  • The Atlanta Braves have hit the Team Total Over in 31 of their last 50 away games (+9.90 Units / 17% ROI)
  • The Atlanta Braves have hit the Game Total Over in 29 of their last 50 away games (+8.35 Units / 15% ROI)
  • The Atlanta Braves have hit the 1st Five Innings (F5) Team Total Over in 22 of their last 35 away games (+8.10 Units / 20% ROI)
  • The Washington Nationals have hit the 1st Five Innings (F5) Team Total Over in 25 of their last 35 games (+14.45 Units / 34% ROI)
  • The Washington Nationals have hit the Team Total Over in 33 of their last 50 games (+13.25 Units / 22% ROI)
  • The Washington Nationals have hit the Game Total Over in 29 of their last 45 games (+11.55 Units / 23% ROI)
  • The Washington Nationals have hit the Moneyline in 24 of their last 50 games (+8.75 Units / 17% ROI)
  • The Washington Nationals have hit the 1st Five Innings (F5) Moneyline in 23 of their last 50 games (+6.85 Units / 13% ROI)

Braves Against the Spread (ATS) Record

Against the spread this season, the Braves are 15-9 against the Run Line (+10.25 Units / 39.73% ROI).

  • 16-8 when betting on the Moneyline for +4.75 Units / 14.05% ROI
  • 11-12 when betting on the total runs Over for -2.05 Units / -7.69% ROI
  • 12-11 when betting on the total runs Under for +0.3 Units / 1.15% ROI

Nationals Against the Spread (ATS) Record

Against the spread this season, the Nationals are 14-9 against the Run Line (+3.05 Units / 9.81% ROI).

  • 11-13 when betting on the Moneyline for +3.75 Units / 15.43% ROI
  • 17-7 when betting on the total runs Over for +9.45 Units / 36% ROI
  • 7-17 when betting on the total runs Under for -11.8 Units / -44.36% ROI

Nationals vs Braves Home Run Prop Bets Today

Yes
Matt Olson +340
Ronald Acuna Jr. +350
Austin Riley +350
Drake Baldwin +425
James Wood +450

Nationals vs Braves Total Hits Prop Bets Today

Over Under
Curtis Mead 0.5 -250 0.5 +185
Drake Baldwin 0.5 -250 0.5 +180
James Wood 0.5 -235 0.5 +175
Daylen Lile 0.5 -235 0.5 +175
Ozzie Albies 0.5 -225 0.5 +165

Nationals vs Braves Strikeout Prop Bets Today

Over Under
Matt Olson 0.5 -235 0.5 +170
Brady House 0.5 -235 0.5 +175
Joey Wiemer 0.5 -190 0.5 +140
Austin Riley 0.5 -190 0.5 +140
Ronald Acuna Jr. 0.5 -165 0.5 +125

Braves Keys to the Game vs. the Nationals

The Braves were just 7-40 (.149) when allowing 2 or more home runs in the 2025 season — 2nd lowest in MLB; League Avg: .301.

The Braves are just 14-74 (.159) when allowing 2 or more home runs since the 2024 season — lowest in MLB; League Avg: .295.

The Braves are 16-8 (.667) this season — tied for 3rd best in MLB; League Avg: .500.

The Braves were 10-67 (.130) when trailing entering the 8th inning in the 2025 season — 4th best in MLB; League Avg: .090.

Nationals Keys to the Game vs. the Braves

The Nationals are just 3-7 (.300) after a win this season — 2nd lowest in MLB; League Avg: .536.

The Nationals are just 3-8 (.273) at home this season — lowest in MLB; League Avg: .538.

The Nationals are just 34-57 (.370) at home since the 2025 season — 2nd lowest in MLB; League Avg: .542.

The Nationals are 7-2 (.778) when tied entering the 8th inning since the 2025 season — best in MLB; League Avg: .500.

The Braves are batting .293 at home this season — best in MLB.

The Braves are batting .272 this season — 2nd best in MLB.

Braves hitters are slugging .305 on pitches out of the zone this season — best in MLB.

Braves hitters are slugging .448 this season — 2nd best in MLB.

The Nationals are batting just .178 when facing the starting pitcher for the 3rd time in a game this season — 2nd lowest in MLB.

Nationals hitters had an OPS of just .640 (1,704 PA’s) against LHP in the 2025 season — 3rd lowest in MLB.

Nationals hitters have struck out in just 19% of their PA’s against RHP this season — 2nd best in MLB.

The Nationals are batting .194 with two-strikes this season — best in MLB.

Braves pitchers have induced opposing hitters to ground into 23 double plays in 146 opportunities (16%) this season — best in MLB.

Braves pitchers had a strikeout rate of 46% with two-strikes in the 2024 season — best in MLB; League Avg: 42%.

Braves pitchers have walked 6% of batters when facing the leadoff batter in the inning this season — 4th best in MLB.

Opponents had a miss rate of 27% against Braves pitchers in the 2025 season — 4th best in MLB.

Nationals pitchers have a strikeout rate of just 36% with two-strikes this season — 2nd lowest in MLB.

Nationals pitchers had an ERA of 5.34 (1424.2 IP) in the 2025 season — 2nd highest in MLB.

Nationals pitchers have an ERA of 5.39 (1641.2 IP) since the 2025 season — 2nd highest in MLB.

The Nationals have allowed 6.01 runs per game (553/92) at home since the 2025 season — 2nd highest in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.