Brewers vs Tigers Prediction, Odds & Player Prop Bets Today – MLB, Apr 21

Detroit Tigers' Parker Meadows reacts after hitting a double against the Oakland Athletics during the third inning of a baseball game Sunday, Sept. 24, 2023, in Oakland, Calif.
(AP Photo/Godofredo A. Vรกsquez)
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  • The Brewers are -105 favorites vs the Tigers
  • Brewers vs Tigers Over / Under today: 8.5 Runs
  • Brewers / Tigers TV Channel: DSN | BRTV

The Milwaukee Brewers (-105) visit Comerica Park to take on the Detroit Tigers (-115) on April 21, 2026. First pitch is scheduled for 6:40 pm in Detroit, MI.

This season, the Brewers are 12-9 against the spread (ATS), while the Tigers are 11-11 ATS.

Brewers vs Tigers Starting Pitchers Today:

  • Brewers starting pitcher: Kyle Harrison 1-1, 3.22 ERA
  • Tigers starting pitcher: Keider Montero 1-1, 3.31 ERA

Brewers vs. Tigers Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Brewers-1.5 +155O 8.5 -118-105
Tigers +1.5 -190U 8.5 -102-115

Brewers vs Tigers Prediction for Today’s Game

Based on recent trends the model predicts the Tigers will win Tuesday‘s MLB game with 51.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Brewers players for Tuesday‘s game, looking at profitable historical betting trends:

Best Brewers Player Prop Bets Today:

  • Brice Turang has hit the Walks Over in 15 of his last 20 games (+16.55 Units / 83% ROI)
  • Brice Turang has hit the Hits Under in 13 of his last 20 away games (+11.95 Units / 49% ROI)
  • Brice Turang has hit the Home Runs Over in 2 of his last 7 games (+10.90 Units / 156% ROI)
  • Sal Frelick has hit the Hits Runs and RBIs Under in 18 of his last 25 games (+10.00 Units / 31% ROI)
  • William Contreras has hit the Total Bases Over in 13 of his last 20 games (+8.40 Units / 37% ROI)

And here are some favorite MLB player prop bets for Tigers players for Tuesday‘s game, looking at profitable historical betting trends:

Best Tigers Player Prop Best Bets Today:

  • Dillon Dingler has hit the Home Runs Over in 3 of his last 6 games (+21.00 Units / 350% ROI)
  • Wenceel Perez has hit the Total Bases Under in 17 of his last 20 games (+15.75 Units / 61% ROI)
  • Kevin McGonigle has hit the Walks Over in his last 8 games at home (+13.60 Units / 170% ROI)
  • Wenceel Perez has hit the Hits Under in 14 of his last 20 games (+13.35 Units / 67% ROI)
  • Wenceel Perez has hit the Singles Under in 20 of his last 25 games (+13.30 Units / 38% ROI)
  • The Milwaukee Brewers have covered the Run Line in 29 of their last 50 away games (+9.20 Units / 15% ROI)
  • The Milwaukee Brewers have hit the Team Total Under in 16 of their last 22 away games (+9.00 Units / 34% ROI)
  • The Milwaukee Brewers have covered the 1st Five Innings (F5) Run Line in 29 of their last 50 away games (+5.80 Units / 10% ROI)
  • The Milwaukee Brewers have hit the Moneyline in 28 of their last 50 away games (+5.10 Units / 9% ROI)
  • The Milwaukee Brewers have hit the 1st Five Innings (F5) Team Total Over in 13 of their last 21 games (+4.85 Units / 20% ROI)
  • The Detroit Tigers have hit the Game Total Over in 28 of their last 45 games at home (+13.70 Units / 27% ROI)
  • The Detroit Tigers have hit the 1st Five Innings (F5) Team Total Over in 31 of their last 50 games at home (+11.45 Units / 20% ROI)
  • The Detroit Tigers have hit the Moneyline in 9 of their last 10 games at home (+7.60 Units / 55% ROI)
  • The Detroit Tigers have covered the Run Line in 7 of their last 10 games at home (+7.00 Units / 64% ROI)
  • The Detroit Tigers have hit the Team Total Over in 24 of their last 40 games at home (+6.75 Units / 15% ROI)

Brewers Against the Spread (ATS) Record

Against the spread this season, the Brewers are 13-8 against the Run Line (+7.35 Units / 29.64% ROI).

  • 12-9 when betting on the Moneyline for -0.8 Units / -2.79% ROI
  • 12-9 when betting on the total runs Over for +1.9 Units / 8.12% ROI
  • 9-12 when betting on the total runs Under for -4.05 Units / -17.72% ROI

Tigers Against the Spread (ATS) Record

Against the spread this season, the Tigers are 11-11 against the Run Line (+0.4 Units / 1.4% ROI).

  • 12-11 when betting on the Moneyline for -1.3 Units / -4.38% ROI
  • 10-11 when betting on the total runs Over for -2.25 Units / -8.84% ROI
  • 11-10 when betting on the total runs Under for +0 Units / 0% ROI

Tigers vs Brewers Home Run Prop Bets Today

Yes
Gary Sanchez +390
William Contreras +475
Jake Bauers +475
Riley Greene +550
Spencer Torkelson +550

Tigers vs Brewers Total Hits Prop Bets Today

Over Under
William Contreras 0.5 -250 0.5 +180
Sal Frelick 0.5 -235 0.5 +175
Kevin McGonigle 0.5 -225 0.5 +165
Brice Turang 0.5 -220 0.5 +160
Riley Greene 0.5 -200 0.5 +150

Tigers vs Brewers Strikeout Prop Bets Today

Over Under
Riley Greene 0.5 -275 0.5 +190
Brandon Lockridge 0.5 -250 0.5 +180
Spencer Torkelson 0.5 -235 0.5 +175
Jake Bauers 0.5 -235 0.5 +175
Gary Sanchez 0.5 -235 0.5 +175

Brewers Keys to the Game vs. the Tigers

The Brewers are 2-5 (.286) when trailing entering the 8th inning this season — tied for best in MLB; League Avg: .107.

The Brewers were 71-7 (.910) when they scored 5 or more runs in the 2025 season — 2nd best in MLB; League Avg: .797.

The Brewers are just 7-4 (.636) when leading entering the 7th inning this season — tied for lowest in MLB; League Avg: .867.

The Brewers are 81-9 (.900) when scoring 5 or more runs since the 2025 season — 2nd best in MLB; League Avg: .793.

Tigers Keys to the Game vs. the Brewers

The Tigers are 8-1 (.889) at home this season — best in MLB; League Avg: .546.

The Tigers were just 4-56 (.067) when trailing entering the 7th inning in the 2025 season — 2nd lowest in MLB; League Avg: .124.

The Tigers were 47-9 (.839) when they had 10 or more hits in the 2025 season — 3rd best in MLB; League Avg: .743.

The Tigers are 84-24 (.778) when allowing 4 or fewer runs since the 2025 season — tied for best in MLB; League Avg: .715.

Brewers hitters had an OBP of .339 (3,229 PA’s) on the road in the 2025 season — best in MLB.

Brewers hitters have a swing rate of just 45% since the 2025 season — lowest in MLB.

Brewers hitters put 40% of their swings in play against LHP in the 2025 season — highest in MLB.

Brewers hitters chased just 19% pitches when the pitcher was behind in the count in the 2025 season — lowest in MLB.

Tigers hitters have chased 19% of pitches out of the zone in non-two strike counts this season — lowest in MLB.

Tigers hitters slugged .439 against LHP in the 2025 season — 3rd best in MLB.

Tigers hitters have struck out in 24% of their PA’s against RHP since the 2025 season — tied for 3rd highest in MLB.

The Tigers batted .265 against LHP in the 2025 season — 2nd best in MLB.

Brewers pitchers have picked-off 8 runners this season — most in MLB.

Brewers pitchers have picked-off 7 runners from first base this season — most in MLB.

Brewers pitchers have a strikeout rate of just 19% over the last 14 days — 4th lowest in MLB.

Brewers pitchers have an ERA of 3.62 (1629.0 IP) since the 2025 season — 3rd best in MLB.

Tigers pitchers walked 6% of batters when facing the leadoff batter in the inning in the 2025 season — 2nd best in MLB.

Tigers pitchers have walked 6% of batters when facing the leadoff batter in the inning since the 2025 season — best in MLB.

Tigers pitchers had a first-pitch strike rate of 65% in the 2025 season — tied for highest in MLB.

Tigers pitchers have walked 7% of batters when facing the leadoff batter in the inning since the 2024 season — tied for 3rd best in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.