• The Tigers are -140 favorites vs the Brewers
• Brewers vs Tigers Over / Under today: 7.5 Runs
• Brewers / Tigers TV Channel: DSN | BRTV

The Milwaukee Brewers (+115) visit Comerica Park to take on the Detroit Tigers (-140) on April 22, 2026. First pitch is scheduled for 6:40 pm in Detroit, MI.

This season, the Brewers are 13-9 against the spread (ATS), while the Tigers are 11-12 ATS.

Brewers vs Tigers Starting Pitchers Today:

• Brewers starting pitcher: Chad Patrick 1-0, 0.95 ERA
• Tigers starting pitcher: Casey Mize 1-1, 2.78 ERA

Brewers vs. Tigers Odds, Run Line, Over/Under & Moneyline

Brewers vs Tigers Prediction for Today’s Game

Based on recent trends the model predicts the Tigers will win Wednesday‘s MLB game with 52.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Brewers vs Tigers and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Brewers players for Wednesday‘s game, looking at profitable historical betting trends:

Best Brewers Player Prop Bets Today:

• Brice Turang has hit the Walks Over in 14 of his last 20 games (+13.75 Units / 69% ROI)
• Brice Turang has hit the Hits Under in 13 of his last 20 away games (+11.95 Units / 49% ROI)
• William Contreras has hit the Total Bases Over in 14 of his last 20 games (+11.45 Units / 53% ROI)
• Sal Frelick has hit the Hits Runs and RBIs Under in 18 of his last 25 games (+10.15 Units / 31% ROI)
• Brice Turang has hit the Home Runs Over in 2 of his last 8 games (+9.90 Units / 124% ROI)

And here are some favorite MLB player prop bets for Tigers players for Wednesday‘s game, looking at profitable historical betting trends:

Best Tigers Player Prop Best Bets Today:

• Dillon Dingler has hit the Home Runs Over in 3 of his last 7 games (+20.00 Units / 286% ROI)
• Kevin McGonigle has hit the Walks Over in 8 of his last 9 games at home (+12.60 Units / 140% ROI)
• Kerry Carpenter has hit the Singles Under in 20 of his last 25 games at home (+12.00 Units / 30% ROI)
• Dillon Dingler has hit the Runs Over in 8 of his last 10 games at home (+9.65 Units / 96% ROI)
• Gleyber Torres has hit the Total Bases Over in 10 of his last 15 games at home (+7.95 Units / 46% ROI)

Brewers Best Bets Today:

• The Milwaukee Brewers have covered the Run Line in 30 of their last 50 away games (+11.45 Units / 18% ROI)
• The Milwaukee Brewers have hit the Team Total Under in 16 of their last 23 away games (+8.00 Units / 29% ROI)
• The Milwaukee Brewers have covered the 1st Five Innings (F5) Run Line in 30 of their last 50 away games (+7.85 Units / 13% ROI)
• The Milwaukee Brewers have hit the Moneyline in 29 of their last 50 away games (+7.50 Units / 13% ROI)
• The Milwaukee Brewers have hit the 1st Five Innings (F5) Team Total Over in 14 of their last 22 games (+5.85 Units / 23% ROI)

Tigers Best Bets Today:

• The Detroit Tigers have hit the Game Total Over in 28 of their last 45 games at home (+13.70 Units / 28% ROI)
• The Detroit Tigers have hit the 1st Five Innings (F5) Team Total Over in 30 of their last 50 games at home (+9.45 Units / 16% ROI)
• The Detroit Tigers have hit the Team Total Over in 25 of their last 40 games at home (+9.05 Units / 20% ROI)
• The Detroit Tigers have hit the Moneyline in 9 of their last 11 games at home (+6.50 Units / 43% ROI)
• The Detroit Tigers have covered the Run Line in 7 of their last 11 games at home (+5.50 Units / 44% ROI)

Brewers Against the Spread (ATS) Record

Against the spread this season, the Brewers are 14-8 against the Run Line (+8.6 Units / 33.33% ROI).

• 13-9 when betting on the Moneyline for +0.2 Units / 0.67% ROI
• 13-9 when betting on the total runs Over for +2.9 Units / 11.84% ROI
• 9-13 when betting on the total runs Under for -5.15 Units / -21.5% ROI

Tigers Against the Spread (ATS) Record

Against the spread this season, the Tigers are 11-12 against the Run Line (-1.1 Units / -3.66% ROI).

• 12-12 when betting on the Moneyline for -2.4 Units / -7.79% ROI
• 11-11 when betting on the total runs Over for -1.25 Units / -4.71% ROI
• 11-11 when betting on the total runs Under for -1.1 Units / -4.19% ROI

Tigers vs Brewers Home Run Prop Bets Today

Tigers vs Brewers Total Hits Prop Bets Today

Tigers vs Brewers Strikeout Prop Bets Today

Brewers Keys to the Game vs. the Tigers

The Brewers are 2-5 (.286) when trailing entering the 8th inning this season — best in MLB; League Avg: .105.

The Brewers were 71-7 (.910) when they scored 5 or more runs in the 2025 season — 2nd best in MLB; League Avg: .797.

The Brewers are 82-9 (.901) when scoring 5 or more runs since the 2025 season — 2nd best in MLB; League Avg: .793.

The Brewers are 51-40 (.560) on the road since the 2025 season — best in MLB; League Avg: .458.

Tigers Keys to the Game vs. the Brewers

The Tigers are 3-9 (.250) when trailing entering the 8th inning this season — tied for 3rd best in MLB; League Avg: .105.

The Tigers were just 4-56 (.067) when trailing entering the 7th inning in the 2025 season — 2nd lowest in MLB; League Avg: .124.

The Tigers were 78-1 (.987) when leading entering the 9th inning in the 2025 season — 2nd best in MLB; League Avg: .956.

The Tigers were 47-9 (.839) when they had 10 or more hits in the 2025 season — 3rd best in MLB; League Avg: .743.

Brewers Hitting Stats & Trends

Brewers hitters have an OBP of .340 (3,634 PA’s) on the road since the 2025 season — best in MLB.

Brewers hitters have chased just 19% pitches with the pitcher behind in the count since the 2025 season — lowest in MLB.

Brewers hitters had a swing rate of just 45% in the 2025 season — lowest in MLB.

Brewers hitters had an OBP of .339 (3,229 PA’s) on the road in the 2025 season — best in MLB.

Tigers Hitting Stats & Trends

The Tigers batted .265 against LHP in the 2025 season — 2nd best in MLB.

Tigers hitters had an OPS of .774 (1,702 PA’s) against LHP in the 2025 season — 2nd best in MLB.

Tigers hitters are slugging .464 at home this season — best in MLB.

Tigers hitters are slugging just .311 against LHP this season — 5th lowest in MLB.

Brewers Pitching Stats & Trends

Brewers pitchers have picked-off 8 runners this season — most in MLB.

Brewers pitchers have picked-off 7 runners from first base this season — most in MLB.

Brewers pitchers had an ERA of 3.59 (1442.0 IP) in the 2025 season — 2nd best in MLB.

Brewers pitchers have 41 three-pitch strikeouts this season — tied for 5th most in MLB.

Tigers Pitching Stats & Trends

Tigers pitchers walked 6% of batters when facing the leadoff batter in the inning in the 2025 season — 2nd best in MLB.

Tigers pitchers have walked 6% of batters when facing the leadoff batter in the inning since the 2025 season — best in MLB.

Opponents have a groundball rate of just 37% against Tigers pitchers over the past seven days (7 games) — tied for 3rd lowest in MLB.

Tigers pitchers have 22 three-pitch strikeouts this season — tied for 4th fewest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

Bet now on Brewers vs Tigers and all games with BetMGM

Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.