• The Cardinals are -110 favorites vs the Angels
• Cardinals vs Angels Over / Under today: 9 Runs
• Cardinals / Angels TV Channel: CATV | ABTV

The St. Louis Cardinals (-110) visit Angel Stadium of Anaheim to take on the Los Angeles Angels (-110) on July 21, 2026. First pitch is scheduled for 9:38 pm in Anaheim, CA.

This season, the Cardinals are against the spread (ATS), while the Angels are ATS.

Cardinals vs Angels Starting Pitchers Today:

• Cardinals starting pitcher: Matthew Liberatore 5-6, 5.00 ERA
• Angels starting pitcher: Walbert Urena 5-7, 2.87 ERA

Cardinals vs. Angels Odds, Run Line, Over/Under & Moneyline

Cardinals vs Angels Prediction for Today’s Game

Based on recent trends the model predicts the Angels will win Tuesday‘s MLB game with 52.7% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Cardinals vs Angels and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Cardinals players for Tuesday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Bets Today:

• Nathan Church has hit the Home Runs Over in 3 of his last 9 away games (+20.50 Units / 228% ROI)
• Blaze Jordan has hit the Runs Under in 17 of his last 20 games (+11.05 Units / 26% ROI)
• Jordan Walker has hit the Hits Runs and RBIs Over in 16 of his last 20 games (+10.80 Units / 43% ROI)
• Ivan Herrera has hit the Total Bases Under in 19 of his last 25 games (+10.10 Units / 24% ROI)
• Lars Nootbaar has hit the Walks Under in 13 of his last 15 away games (+9.45 Units / 38% ROI)

And here are some favorite MLB player prop bets for Angels players for Tuesday‘s game, looking at profitable historical betting trends:

Best Angels Player Prop Best Bets Today:

• Jo Adell has hit the Hits Under in 15 of his last 25 games (+11.20 Units / 40% ROI)
• Logan O’Hoppe has hit the Runs Under in 20 of his last 25 games at home (+10.60 Units / 20% ROI)
• Jo Adell has hit the Hits Runs and RBIs Under in 18 of his last 25 games (+10.05 Units / 32% ROI)
• Nolan Schanuel has hit the Total Bases Over in 13 of his last 20 games at home (+9.80 Units / 42% ROI)
• Denzer Guzman has hit the Singles Over in 11 of his last 15 games (+8.90 Units / 58% ROI)

Cardinals Best Bets Today:

• The St. Louis Cardinals have hit the Team Total Over in 31 of their last 45 away games (+15.45 Units / 29% ROI)
• The St. Louis Cardinals have covered the Run Line in 28 of their last 45 away games (+9.85 Units / 15% ROI)
• The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 24 of their last 45 away games (+9.40 Units / 20% ROI)
• The St. Louis Cardinals have hit the Moneyline in 25 of their last 45 away games (+8.55 Units / 18% ROI)
• The St. Louis Cardinals have hit the Game Total Under in 16 of their last 24 games (+8.40 Units / 32% ROI)

Angels Best Bets Today:

• The Los Angeles Angels have hit the Team Total Under in 31 of their last 50 games at home (+9.35 Units / 16% ROI)
• The Los Angeles Angels have hit the Game Total Under in 27 of their last 45 games at home (+8.45 Units / 17% ROI)
• The Los Angeles Angels have covered the 1st Five Innings (F5) Run Line in 27 of their last 45 games (+7.30 Units / 14% ROI)
• The Los Angeles Angels have hit the 1st Five Innings (F5) Moneyline in 26 of their last 50 games at home (+6.75 Units / 11% ROI)
• The Los Angeles Angels have hit the 1st Five Innings (F5) Team Total Under in their last 5 games (+5.20 Units / 74% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are against the Run Line ( Units / ROI).

• away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• away total over record when betting on the total runs Over for over units Units / over ROI ROI
• away total under record when betting on the total runs Under for under units Units / under ROI ROI

Angels Against the Spread (ATS) Record

Against the spread this season, the Angels are against the Run Line ( Units / ROI).

• home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• home total over record when betting on the total runs Over for over units Units / over ROI ROI
• home total under record when betting on the total runs Under for under units Units / under ROI ROI

Angels vs Cardinals Home Run Prop Bets Today

Angels vs Cardinals Total Hits Prop Bets Today

Angels vs Cardinals Strikeout Prop Bets Today

Cardinals Keys to the Game vs. the Angels

The Cardinals were just 7-11 (.389) when tied entering the 8th inning in the 2025 season — tied for 5th lowest in MLB; League Avg: .500.

The Cardinals were 18-9 (.667) when tied entering the 7th inning in the 2024 season — tied for 3rd best in MLB; League Avg: .498.

The Cardinals were 69-1 (.986) when leading entering the 9th inning in the 2024 season — tied for 2nd best in MLB; League Avg: .949.

Angels Keys to the Game vs. the Cardinals

The Angels are just 33-8 (.805) when leading entering the 9th inning this season — lowest in MLB; League Avg: .947.

The Angels are just 3-10 (.231) when tied entering the 8th inning this season — 2nd lowest in MLB; League Avg: .500.

The Angels are just 40-61 (.396) this season — 2nd lowest in MLB; League Avg: .500.

The Angels are just 3-26 (.103) when allowing 10 or more hits this season — lowest in MLB; League Avg: .248.

Cardinals Hitting Stats & Trends

Cardinals hitters have struck out in just 17% of their PA’s against LHP this season — 2nd best in MLB.

Cardinals hitters are slugging just .366 at home this season — 3rd lowest in MLB.

Cardinals hitters have an OPS of just .671 (1,884 PA’s) at home this season — 3rd lowest in MLB.

Cardinals hitters have 76 extra-base hits out of 247 total hits (just 31%) against LHP this season — 4th lowest in MLB.

Angels Hitting Stats & Trends

Angels hitters are slugging just .346 at home this season — lowest in MLB.

Angels hitters have an OPS of just .649 (1,837 PA’s) at home this season — lowest in MLB.

The Angels have a winning percentage of just 33% on the road this season — tied for lowest in MLB.

Angels hitters have struck out in 25% of their PA’s this season — highest in MLB.

Cardinals Pitching Stats & Trends

Opponents have a miss rate of just 22% against Cardinals pitchers this season — lowest in MLB.

The Cardinals pitchers have allowed their opponents to score first in just 32% of their games on the road this season — 2nd lowest in MLB.

Cardinals pitchers have a strikeout rate of just 20% this season — tied for 3rd lowest in MLB.

Opponents have a groundball rate of 46% against Cardinals pitchers this season — tied for highest in MLB.

Angels Pitching Stats & Trends

Angels pitchers have walked 11% of batters this season — 3rd highest in MLB.

Opponents have a miss rate of 28% against Angels pitchers this season — best in MLB.

The Angels pitchers have allowed their opponents to score first in 59% of their games on the road this season — 2nd highest in MLB.

Angels pitchers have won only 16% of games in which they have allowed their opponent to score in three different innings this season — tied for lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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