Cardinals vs Brewers Prediction, Odds & Player Prop Bets Today – MLB, Sep 27

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MLB betting odds, predictions and betting odds for today's games
(AP Photo)
BetMGM Betting @BETMGM Sep 27, 2022, 3:30 PM
  • The Cardinals (89-65) are -115 favorites vs the Brewers (82-71)
  • Cardinals starting pitcher: Miles Mikolas (11-13), 3.35 ERA
  • Brewers starting pitcher: Adrian Houser (6-9), 4.62 ERA
  • Watch the game on MLB Network

The St. Louis Cardinals (-115) visit American Family Field to take on the Milwaukee Brewers (-105) on Tuesday, September 27, 2022. First pitch is scheduled for 7:40pm EDT in Milwaukee.

The Cardinals are betting favorites in this MLB matchup, with the run line sitting at -1.5 (+140).

The Cardinals vs Brewers Over/Under is 8.5 total runs for the game.

So far this season, the Cardinals are 89-65 against the spread (ATS), while the Brewers are 65-88 ATS.

Cardinals vs. Brewers Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cardinals-1.5 +140O 8.5 -110-115
Brewers +1.5 -165U 8.5 -110-105

Cardinals vs Brewers Prediction for Today’s Game

Based on recent trends the model predicts the Brewers will win Tuesday‘s matchup with 57.4% confidence.

This prediction factors in starting pitchers, recent team and player hitting performances, the last 5 games for both the Cardinals and Brewers and up-to-date player injuries.


Looking for a risk-free bet up to $1,000? Bet now on Brewers vs Cardinals and all MLB games with BetMGM


Best Cardinals Player Prop Bets Today

We’ve highlighted some favorite MLB player prop bets for Cardinals players for Tuesday‘s game, looking at profitable historical betting trends:

  • Jose Quintana has hit the Earned Runs Under in 20 of his last 25 games (+14.30 Units / 47% ROI)
  • Paul Goldschmidt has hit the RBIs Under in his last 11 away games (+11.00 Units / 50% ROI)
  • Paul Goldschmidt has hit the Runs Under in 11 of his last 12 games (+9.80 Units / 56% ROI)
  • Tommy Edman has hit the Hits Under in 8 of his last 11 games (+8.40 Units / 62% ROI)
  • Tommy Edman has hit the Runs Under in 14 of his last 18 games (+8.05 Units / 29% ROI)

Best Brewers Player Prop Best Bets Today

And here are some favorite MLB player prop bets for Brewers players for Tuesday‘s game, looking at profitable historical betting trends:

  • Willy Adames has hit the RBIs Over in 24 of his last 45 games at home (+11.25 Units / 25% ROI)
  • Willy Adames has hit the Total Bases Over in 17 of his last 24 games at home (+10.85 Units / 39% ROI)
  • Eric Lauer has hit the Strikeouts Under in 16 of his last 21 games (+9.35 Units / 30% ROI)
  • Freddy Peralta has hit the Strikeouts Under in his last 9 games (+9.05 Units / 68% ROI)
  • Hunter Renfroe has hit the Singles Over in 25 of his last 46 games (+9.05 Units / 19% ROI)

Brewers vs Cardinals Home Run Prop Bets Today

Over Under
Andrew McCutchen 0.5 +500 0.5 -1100
Christian Yelich 0.5 +550 0.5 -1400
Garrett Mitchell 0.5 +800 0.5 -3000
Hunter Renfroe 0.5 +375 0.5 -700
Kolten Wong 0.5 +600 0.5 -1600

Brewers vs Cardinals Total Hits Prop Bets Today

Over Under
Andrew McCutchen 0.5 -165 0.5 +115
Christian Yelich 0.5 -250 0.5 +165
Garrett Mitchell 0.5 -120 0.5 -115
Hunter Renfroe 0.5 -190 0.5 +135
Kolten Wong 0.5 -190 0.5 +130

Brewers vs Cardinals RBI Prop Bets Today

Over Under
Andrew McCutchen 0.5 +210 0.5 -350
Christian Yelich 0.5 +230 0.5 -350
Garrett Mitchell 0.5 +280 0.5 -450
Hunter Renfroe 0.5 +170 0.5 -250
Kolten Wong 0.5 +230 0.5 -350

Brewers vs Cardinals Strikeout Prop Bets Today

Over Under
Adrian Houser 2.5 -140 2.5 +100
  • The St. Louis Cardinals have covered the Run Line in 83 of their last 149 games (+12.05 Units / 6% ROI)
  • The St. Louis Cardinals have hit the Moneyline in 44 of their last 67 games (+11.10 Units / 10% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Total Over in 35 of their last 65 away games (+9.75 Units / 14% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 10 of their last 11 away games (+9.50 Units / 73% ROI)
  • The St. Louis Cardinals have hit the Team Total Under in 28 of their last 48 away games (+6.60 Units / 12% ROI)
  • The Milwaukee Brewers have hit the 1st Five Innings (F5) Total Over in 71 of their last 133 games (+12.90 Units / 9% ROI)
  • The Milwaukee Brewers have hit the Team Total Over in 27 of their last 42 games at home (+10.70 Units / 22% ROI)
  • The Milwaukee Brewers have covered the 1st Five Innings (F5) Run Line in 42 of their last 69 games at home (+10.32 Units / 12% ROI)
  • The Milwaukee Brewers have hit the Game Total Over in 70 of their last 133 games (+5.15 Units / 3% ROI)
  • The Milwaukee Brewers have hit the Moneyline in 15 of their last 23 games at home (+5.05 Units / 13% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this MLB season, the Cardinals have gone 85-69 against the Run Line (+10.7 Units / 5.53% ROI).

  • 89-65 when betting on the Moneyline for +7.4 Units / 3.34% ROI
  • 73-76 when betting on the total runs Over for -10.9 Units / -6.42% ROI
  • 76-73 when betting on the total runs Under for -3.9 Units / -2.3% ROI

Brewers Against the Spread (ATS) Record

Against the spread this MLB season, the Cardinals have gone 65-88 against the Run Line (-30.75 Units / -16.66% ROI).

  • 82-71 when betting on the Moneyline for -19.75 Units / -8.14% ROI
  • 75-71 when betting on the total runs Over for -2.65 Units / -1.57% ROI
  • 71-75 when betting on the total runs Under for -10.25 Units / -6.09% ROI

Miles Mikolas has allowed an average Exit Velocity of just 75.7 MPH on pitches out of the zone since the start of last season (125 balls in play) — 3rd best in MLB among starting pitchers with at least 157 total IP; League Avg: 80.2

Miles Mikolas has thrown inside pitches 46% of the time (658/1,433) vs left-handed batters this season — 2nd highest among qualified SPs in MLB; League Avg: 33% — 96th Percentile.

Miles Mikolas has a strikeout rate of just 17% (30 SO in 177 PAs) on low non-fastballs this season — 2nd lowest among qualified SPs in MLB; League Avg: 35% — fourth Percentile.

52% of Miles Mikolas’ called strikeouts are inside this season — 5th highest among qualified SPs in MLB; League Avg: 32% — 91st Percentile.

Adrian Houser: Brewers Starting Pitcher Stats & Trends

Adrian Houser has a strikeout rate of just 9% (3 SO in 35 PAs) with two-strikes this month (4 games) — lowest in MLB among starting pitchers with at least 10 total IP; League Avg: 42% — 0 Percentile.

Adrian Houser has thrown at least two strikes in his first three pitches to 53% (180/338) of opposing batters this season — 2nd lowest in MLB among starting pitchers with at least 76 total IP; League Avg: 65% — first Percentile.

Hitters have chased just 95 of Adrian Houser’s 439 breaking balls down out of the zone (chase rate of 22%) since the start of last season — 2nd lowest in MLB among starting pitchers with at least 157 total IP; League Avg: 35% — second Percentile.

Adrian Houser has not struck out a hitter in his last 46 PAs against a RHH dating back to September 5th — this is the longest active streak among active MLB players.

Cardinals Keys to the Game vs. the Brewers

The Cardinals are 15-4 (.789) when tied entering the 8th inning this season — best in MLB; League Avg: .500.

The Cardinals are 15-9 (.625) when tied entering the 7th inning this season — 6th best in MLB; League Avg: .500.

The Cardinals are 49-9 (.845) when hitting 2 or more home runs this season — 2nd best in MLB; League Avg: .706.

The Cardinals are 46-10 (.821) when totaling 10 or more hits this season — 6th best in MLB; League Avg: .726.

Brewers Keys to the Game vs. the Cardinals

The Brewers are 16-8 (.667) when tied entering the 7th inning this season — tied for 4th best in MLB; League Avg: .500.

The Brewers are just 58-11 (.841) when leading entering the 7th inning this season — 9th lowest in MLB; League Avg: .881.

The Brewers are 8-55 (.127) when trailing entering the 8th inning this season — 7th best in MLB; League Avg: .085.

The Brewers are 42-30 (.583) at home this season — 8th best in MLB; League Avg: .525.

Cardinals hitters are slugging .469 against LHP since the start of last season — best in MLB; League Avg: .408.

Cardinals hitters have 255 extra-base hits out of 591 total hits (43%) against LHP since the start of last season — best in MLB; League Avg: 35%.

Cardinals hitters have an OPS of .804 (2,574 PA’s) against LHP since the start of last season — best in MLB; League Avg: .726.

Cardinals hitters are slugging .465 against LHP this season — best in MLB; League Avg: .401.

The Brewers are batting just .218 against LHP this season — 2nd lowest in MLB; League Avg: .246.

The Brewers are batting just .224 against LHP since the start of last season — 2nd lowest in MLB; League Avg: .247.

Brewers hitters are averaging 4.08 pitches per plate appearance against LHP this season — 2nd highest in MLB; League Avg: 3.89.

Brewers hitters have 783 strikeouts in 3,139 PA’s (25%) against LHP since the start of last season — 3rd highest in MLB; League Avg: 22%.

Opponents have a miss rate of just 22% against Cardinals pitchers this season — lowest in MLB; League Avg: 26%.

Opponents have a groundball rate of 46% against Cardinals pitchers since the start of last season — 2nd highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 47% against Cardinals pitchers this season — 2nd highest in MLB; League Avg: 43%.

Cardinals pitchers have a strikeout rate of just 38% with two-strikes this season — 3rd lowest in MLB; League Avg: 42%.

Brewers pitchers have a strikeout rate of 47% with two-strikes since the start of last season — tied for best in MLB; League Avg: 43%.

Opponents have a miss rate of 28% against Brewers pitchers this season — 4th best in MLB; League Avg: 26%.

Opponents have a groundball rate of 52% against Brewers pitchers over the last 14 days (12 games) — highest in MLB; League Avg: 43%.

Brewers pitchers have a strikeout rate of 47% with two-strikes since the start of 2020 — best in MLB; League Avg: 43%.

Brewers vs. Cardinals Injuries Tonight That May Affect Prop Bets 

  • Luis Perdomo (Brewers): Calf, D15
  • Alex J Jackson (Brewers): Wrist, D60
  • Trevor Rosenthal (Brewers): Hamstring, D15
  • Miguel Sánchez (Brewers): Elbow, D60
  • Jandel Gustave (Brewers): Forearm, D15
  • Jonathan Davis (Brewers): Elbow, D10
  • Alexander Reyes (Cardinals): Shoulder, D60
  • Tyler O’Neill (Cardinals): Hamstring, D10
  • Jordan Hicks (Cardinals): Neck, D15
  • Drew VerHagen (Cardinals): Hip, D60

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.