Cardinals vs Diamondbacks Prediction, Odds & Player Prop Bets Today – MLB, Aug 21

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MLB betting odds, predictions and betting odds for today's games
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BetMGM Betting @BETMGM Aug 21, 2022, 9:12 AM
  • The Cardinals (68-51) are -130 favorites vs the Diamondbacks (55-65)
  • Cardinals starting pitcher: José Quintana (4-5), 3.37 ERA
  • Diamondbacks starting pitcher: Kenneth Kelly (10-5), 2.80 ERA
  • Watch the game on BSAZ

The St. Louis Cardinals (-130) visit Chase Field to take on the Arizona Diamondbacks (+105) on Sunday, August 21, 2022. First pitch is scheduled for 4:10pm EDT in Phoenix.

The Cardinals are betting favorites in this MLB matchup, with the run line sitting at -1.5 (+125).

The Cardinals vs Diamondbacks Over/Under is 7.5 total runs for the game.

So far this season, the Cardinals are 66-51 against the spread (ATS), while the Diamondbacks are 68-50 ATS.

Cardinals vs. Diamondbacks Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cardinals-1.5 +125O 7.5 -105-130
Diamondbacks +1.5 -155U 7.5 -115+105

Cardinals vs Diamondbacks Prediction for Today’s Game

Based on recent trends the model predicts the Cardinals will win Sunday‘s matchup with 53.4% confidence.

This prediction factors in starting pitchers, recent team and player hitting performances, the last 5 games for both the Cardinals and Diamondbacks and up-to-date player injuries.


Looking for a risk-free bet up to $1,000? Bet now on Diamondbacks vs Cardinals and all MLB games with BetMGM


Best Cardinals Player Prop Bets Today

We’ve highlighted some favorite MLB player prop bets for Cardinals players for Sunday‘s game, looking at profitable historical betting trends:

  • Paul DeJong has hit the Singles Under in 18 of his last 20 away games (+14.30 Units / 36% ROI)
  • Paul Goldschmidt has hit the Runs Over in 21 of his last 27 games (+14.15 Units / 40% ROI)
  • Nolan Arenado has hit the Total Bases Over in 16 of his last 21 away games (+11.50 Units / 46% ROI)
  • Nolan Gorman has hit the Hits Over in 11 of his last 12 games (+10.80 Units / 54% ROI)
  • Miles Mikolas has hit the Earned Runs Under in 18 of his last 24 games (+10.65 Units / 32% ROI)

Best Diamondbacks Player Prop Best Bets Today

And here are some favorite MLB player prop bets for Diamondbacks players for Sunday‘s game, looking at profitable historical betting trends:

  • Christian Walker has hit the Hits Under in 43 of his last 81 games (+22.30 Units / 24% ROI)
  • Christian Walker has hit the Singles Under in 56 of his last 84 games (+13.05 Units / 10% ROI)
  • Christian Walker has hit the Total Bases Under in 54 of his last 81 games (+12.05 Units / 9% ROI)
  • Daulton Varsho has hit the Hits Under in 15 of his last 25 games at home (+12.00 Units / 48% ROI)
  • Alek Thomas has hit the Hits Under in 17 of his last 23 games (+11.90 Units / 29% ROI)
  • The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 23 of their last 35 games (+12.00 Units / 30% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Total Over in 28 of their last 47 away games (+9.50 Units / 18% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 19 of their last 31 games (+6.00 Units / 14% ROI)
  • The Arizona Diamondbacks have covered the 1st Five Innings (F5) Run Line in 30 of their last 42 games (+18.40 Units / 38% ROI)
  • The Arizona Diamondbacks have hit the 1st Five Innings (F5) Total Under in 18 of their last 27 games (+8.95 Units / 31% ROI)
  • The Arizona Diamondbacks have hit the 1st Five Innings (F5) Moneyline in 10 of their last 17 games at home (+0.95 Units / 4% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this MLB season, the Cardinals have gone 66-51 against the Run Line (+12.85 Units / 8.77% ROI).

  • 66-51 when betting on the Moneyline for +8.45 Units / 5.46% ROI
  • 54-59 when betting on the total runs Over for -11.6 Units / -8.96% ROI
  • 59-54 when betting on the total runs Under for -0.1 Units / -0.08% ROI

Diamondbacks Against the Spread (ATS) Record

Against the spread this MLB season, the Cardinals have gone 68-50 against the Run Line (+14.6 Units / 9.59% ROI).

  • 54-64 when betting on the Moneyline for -4.35 Units / -3.26% ROI
  • 51-62 when betting on the total runs Over for -17.1 Units / -13.22% ROI
  • 62-51 when betting on the total runs Under for +4.95 Units / 3.79% ROI

Jose Quintana has a strike rate of just 55% (403/728) when ahead in the count this season — lowest among qualified SPs in MLB; League Avg: 63% — first Percentile.

Jose Quintana has a strike rate of just 62% (371/602) in two strike counts this season — 6th lowest among qualified SPs in MLB; League Avg: 66% — ninth Percentile.

Jose Quintana has a strike rate of just 62% (1,052/1,687) against right-handed batters this season — 3rd lowest among qualified SPs in MLB; League Avg: 66% — fourth Percentile.

Jose Quintana has allowed an OPS of .838 (229 PA’s) versus the bottom of the order since the start of last season — highest in MLB among starting pitchers with at least 139 total IP; League Avg: .621 — 0 Percentile.

Kenneth Kelly: Diamondbacks Starting Pitcher Stats & Trends

Opponents have a miss rate of just 21% (38/181) against Merrill Kelly on the first pitch of at-bats this season — 8th lowest among qualified SPs in MLB; League Avg: 26% — 14th Percentile.

Opponents are hitting just .127 (10-for-79) against Merrill Kelly’s elevated fastball this season — 2nd best among qualified SPs in MLB; League Avg: .220 — 97th Percentile.

Merrill Kelly has allowed an OPS of just .390 (297 PA’s) with two-strikes this season — 10th best among qualified SPs in MLB; League Avg: .474 — 84th Percentile.

34% of Merrill Kelly’s strikeouts are looking this season — 6th highest among qualified SPs in MLB; League Avg: 23% — 92nd Percentile.

Cardinals Keys to the Game vs. the Diamondbacks

The Cardinals are 54-3 (.947) when leading entering the 7th inning this season — 5th best in MLB; League Avg: .887.

The Cardinals are 39-8 (.830) when totaling 10 or more hits this season — 8th best in MLB; League Avg: .725.

The Cardinals are 40-21 (.656) at home this season — 5th best in MLB; League Avg: .529.

The Cardinals are 11-4 (.733) when tied entering the 8th inning this season — 2nd best in MLB; League Avg: .500.

Diamondbacks Keys to the Game vs. the Cardinals

The Diamondbacks are just 97-28 (.776) when leading entering the 7th inning since the 2020 season — lowest in MLB; League Avg: .876.

The Diamondbacks are just 107-19 (.849) when leading entering the 8th inning since the 2020 season — lowest in MLB; League Avg: .914.

The Diamondbacks are just 10-31 (.244) when tied entering the 8th inning since the 2020 season — lowest in MLB; League Avg: .500.

The Diamondbacks are just 15-52 (.224) when scoring 4 or fewer runs this season — tied for 3rd lowest in MLB; League Avg: .295.

Cardinals hitters have 229 extra-base hits out of 534 total hits (43%) against LHP since the start of last season — best in MLB; League Avg: 35%.

Cardinals hitters have an OPS of .803 (2,292 PA’s) against LHP since the start of last season — best in MLB; League Avg: .726.

The Cardinals are batting .351 on the road this month (5 games) — best in MLB; League Avg: .236.

Cardinals hitters are slugging .639 on the road over the last 14 days (5 games) — best in MLB; League Avg: .377.

The Diamondbacks are batting just .217 when facing the starting pitcher for the 3rd time in a game this season — tied for lowest in MLB; League Avg: .266.

The Diamondbacks are batting just .199 in righty-righty matchups since the start of last season — lowest in MLB; League Avg: .243.

The Diamondbacks have a winning percentage of just 31% on the road since the start of last season — 2nd lowest in MLB; League Avg: 47%.

Diamondbacks hitters have an OBP of just .286 (541 PA’s) when facing the starting pitcher for the 3rd time in a game this season — 2nd lowest in MLB; League Avg: .326.

Opponents have a groundball rate of 47% against Cardinals pitchers this season — 2nd highest in MLB; League Avg: 43%.

Opponents have a miss rate of just 22% against Cardinals pitchers this season — 2nd lowest in MLB; League Avg: 25%.

Opponents have a miss rate of just 23% against Cardinals pitchers since the start of last season — 2nd lowest in MLB; League Avg: 26%.

Cardinals pitchers have won 80% of games in which they have allowed their opponent to score in three different innings this month (17 games) — highest in MLB; League Avg: 24%.

Opponents have a miss rate of just 22% against Diamondbacks pitchers since the start of last season — lowest in MLB; League Avg: 26%.

Diamondbacks pitchers have a strikeout rate of just 18% in close and late situations this season — lowest in MLB; League Avg: 25%.

Diamondbacks pitchers have a strikeout rate of just 19% in close and late situations since the start of last season — lowest in MLB; League Avg: 25%.

Diamondbacks pitchers have a strikeout rate of just 19% in close and late situations since the start of 2020 — lowest in MLB; League Avg: 25%.

Diamondbacks vs. Cardinals Injuries Tonight That May Affect Prop Bets 

  • Keynan Middleton (Diamondbacks): Ankle, D15
  • Caleb Smith (Diamondbacks): Hand, D15
  • Tyler Gilbert (Diamondbacks): Elbow, D60
  • Kyle Nelson (Diamondbacks): Back, D15
  • Humberto Castellanos (Diamondbacks): Elbow, D60
  • Ketel Marte (Diamondbacks): Hamstring, Day-to-Day
  • Nicholas Ahmed (Diamondbacks): Shoulder, D60
  • Alexander Reyes (Cardinals): Shoulder, D60
  • Steven Matz (Cardinals): Knee, D15
  • Jack Flaherty (Cardinals): Shoulder, D60
  • Drew VerHagen (Cardinals): Hip, D60

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.