Cardinals vs Diamondbacks Prediction, Odds & Player Prop Bets Today – MLB, Aug 21

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MLB betting odds, predictions and betting odds for today's games
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BetMGM Betting @BETMGM Aug 21, 2022, 9:12 AM
  • The Cardinals (68-51) are -130 favorites vs the Diamondbacks (55-65)
  • Cardinals starting pitcher: José Quintana (4-5), 3.37 ERA
  • Diamondbacks starting pitcher: Kenneth Kelly (10-5), 2.80 ERA
  • Watch the game on BSAZ

The St. Louis Cardinals (-130) visit Chase Field to take on the Arizona Diamondbacks (+105) on Sunday, August 21, 2022. First pitch is scheduled for 4:10pm EDT in Phoenix.

The Cardinals are betting favorites in this MLB matchup, with the run line sitting at -1.5 (+125).

The Cardinals vs Diamondbacks Over/Under is 7.5 total runs for the game.

So far this season, the Cardinals are 66-51 against the spread (ATS), while the Diamondbacks are 68-50 ATS.

Cardinals vs. Diamondbacks Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cardinals-1.5 +125O 7.5 -105-130
Diamondbacks +1.5 -155U 7.5 -115+105

Cardinals vs Diamondbacks Prediction for Today’s Game

Based on recent trends the model predicts the Cardinals will win Sunday‘s matchup with 53.4% confidence.

This prediction factors in starting pitchers, recent team and player hitting performances, the last 5 games for both the Cardinals and Diamondbacks and up-to-date player injuries.


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Best Cardinals Player Prop Bets Today

We’ve highlighted some favorite MLB player prop bets for Cardinals players for Sunday‘s game, looking at profitable historical betting trends:

  • Paul DeJong has hit the Singles Under in 18 of his last 20 away games (+14.30 Units / 36% ROI)
  • Paul Goldschmidt has hit the Runs Over in 21 of his last 27 games (+14.15 Units / 40% ROI)
  • Nolan Arenado has hit the Total Bases Over in 16 of his last 21 away games (+11.50 Units / 46% ROI)
  • Nolan Gorman has hit the Hits Over in 11 of his last 12 games (+10.80 Units / 54% ROI)
  • Miles Mikolas has hit the Earned Runs Under in 18 of his last 24 games (+10.65 Units / 32% ROI)

Best Diamondbacks Player Prop Best Bets Today

And here are some favorite MLB player prop bets for Diamondbacks players for Sunday‘s game, looking at profitable historical betting trends:

  • Christian Walker has hit the Hits Under in 43 of his last 81 games (+22.30 Units / 24% ROI)
  • Christian Walker has hit the Singles Under in 56 of his last 84 games (+13.05 Units / 10% ROI)
  • Christian Walker has hit the Total Bases Under in 54 of his last 81 games (+12.05 Units / 9% ROI)
  • Daulton Varsho has hit the Hits Under in 15 of his last 25 games at home (+12.00 Units / 48% ROI)
  • Alek Thomas has hit the Hits Under in 17 of his last 23 games (+11.90 Units / 29% ROI)
  • The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 23 of their last 35 games (+12.00 Units / 30% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Total Over in 28 of their last 47 away games (+9.50 Units / 18% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 19 of their last 31 games (+6.00 Units / 14% ROI)
  • The Arizona Diamondbacks have covered the 1st Five Innings (F5) Run Line in 30 of their last 42 games (+18.40 Units / 38% ROI)
  • The Arizona Diamondbacks have hit the 1st Five Innings (F5) Total Under in 18 of their last 27 games (+8.95 Units / 31% ROI)
  • The Arizona Diamondbacks have hit the 1st Five Innings (F5) Moneyline in 10 of their last 17 games at home (+0.95 Units / 4% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this MLB season, the Cardinals have gone 66-51 against the Run Line (+12.85 Units / 8.77% ROI).

  • 66-51 when betting on the Moneyline for +8.45 Units / 5.46% ROI
  • 54-59 when betting on the total runs Over for -11.6 Units / -8.96% ROI
  • 59-54 when betting on the total runs Under for -0.1 Units / -0.08% ROI

Diamondbacks Against the Spread (ATS) Record

Against the spread this MLB season, the Cardinals have gone 68-50 against the Run Line (+14.6 Units / 9.59% ROI).

  • 54-64 when betting on the Moneyline for -4.35 Units / -3.26% ROI
  • 51-62 when betting on the total runs Over for -17.1 Units / -13.22% ROI
  • 62-51 when betting on the total runs Under for +4.95 Units / 3.79% ROI

Jose Quintana has a strike rate of just 55% (403/728) when ahead in the count this season — lowest among qualified SPs in MLB; League Avg: 63% — first Percentile.

Jose Quintana has a strike rate of just 62% (371/602) in two strike counts this season — 6th lowest among qualified SPs in MLB; League Avg: 66% — ninth Percentile.

Jose Quintana has a strike rate of just 62% (1,052/1,687) against right-handed batters this season — 3rd lowest among qualified SPs in MLB; League Avg: 66% — fourth Percentile.

Jose Quintana has allowed an OPS of .838 (229 PA’s) versus the bottom of the order since the start of last season — highest in MLB among starting pitchers with at least 139 total IP; League Avg: .621 — 0 Percentile.

Kenneth Kelly: Diamondbacks Starting Pitcher Stats & Trends

Opponents have a miss rate of just 21% (38/181) against Merrill Kelly on the first pitch of at-bats this season — 8th lowest among qualified SPs in MLB; League Avg: 26% — 14th Percentile.

Opponents are hitting just .127 (10-for-79) against Merrill Kelly’s elevated fastball this season — 2nd best among qualified SPs in MLB; League Avg: .220 — 97th Percentile.

Merrill Kelly has allowed an OPS of just .390 (297 PA’s) with two-strikes this season — 10th best among qualified SPs in MLB; League Avg: .474 — 84th Percentile.

34% of Merrill Kelly’s strikeouts are looking this season — 6th highest among qualified SPs in MLB; League Avg: 23% — 92nd Percentile.

Cardinals Keys to the Game vs. the Diamondbacks

The Cardinals are 54-3 (.947) when leading entering the 7th inning this season — 5th best in MLB; League Avg: .887.

The Cardinals are 39-8 (.830) when totaling 10 or more hits this season — 8th best in MLB; League Avg: .725.

The Cardinals are 40-21 (.656) at home this season — 5th best in MLB; League Avg: .529.

The Cardinals are 11-4 (.733) when tied entering the 8th inning this season — 2nd best in MLB; League Avg: .500.

Diamondbacks Keys to the Game vs. the Cardinals

The Diamondbacks are just 97-28 (.776) when leading entering the 7th inning since the 2020 season — lowest in MLB; League Avg: .876.

The Diamondbacks are just 107-19 (.849) when leading entering the 8th inning since the 2020 season — lowest in MLB; League Avg: .914.

The Diamondbacks are just 10-31 (.244) when tied entering the 8th inning since the 2020 season — lowest in MLB; League Avg: .500.

The Diamondbacks are just 15-52 (.224) when scoring 4 or fewer runs this season — tied for 3rd lowest in MLB; League Avg: .295.

Cardinals hitters have 229 extra-base hits out of 534 total hits (43%) against LHP since the start of last season — best in MLB; League Avg: 35%.

Cardinals hitters have an OPS of .803 (2,292 PA’s) against LHP since the start of last season — best in MLB; League Avg: .726.

The Cardinals are batting .351 on the road this month (5 games) — best in MLB; League Avg: .236.

Cardinals hitters are slugging .639 on the road over the last 14 days (5 games) — best in MLB; League Avg: .377.

The Diamondbacks are batting just .217 when facing the starting pitcher for the 3rd time in a game this season — tied for lowest in MLB; League Avg: .266.

The Diamondbacks are batting just .199 in righty-righty matchups since the start of last season — lowest in MLB; League Avg: .243.

The Diamondbacks have a winning percentage of just 31% on the road since the start of last season — 2nd lowest in MLB; League Avg: 47%.

Diamondbacks hitters have an OBP of just .286 (541 PA’s) when facing the starting pitcher for the 3rd time in a game this season — 2nd lowest in MLB; League Avg: .326.

Opponents have a groundball rate of 47% against Cardinals pitchers this season — 2nd highest in MLB; League Avg: 43%.

Opponents have a miss rate of just 22% against Cardinals pitchers this season — 2nd lowest in MLB; League Avg: 25%.

Opponents have a miss rate of just 23% against Cardinals pitchers since the start of last season — 2nd lowest in MLB; League Avg: 26%.

Cardinals pitchers have won 80% of games in which they have allowed their opponent to score in three different innings this month (17 games) — highest in MLB; League Avg: 24%.

Opponents have a miss rate of just 22% against Diamondbacks pitchers since the start of last season — lowest in MLB; League Avg: 26%.

Diamondbacks pitchers have a strikeout rate of just 18% in close and late situations this season — lowest in MLB; League Avg: 25%.

Diamondbacks pitchers have a strikeout rate of just 19% in close and late situations since the start of last season — lowest in MLB; League Avg: 25%.

Diamondbacks pitchers have a strikeout rate of just 19% in close and late situations since the start of 2020 — lowest in MLB; League Avg: 25%.

Diamondbacks vs. Cardinals Injuries Tonight That May Affect Prop Bets 

  • Keynan Middleton (Diamondbacks): Ankle, D15
  • Caleb Smith (Diamondbacks): Hand, D15
  • Tyler Gilbert (Diamondbacks): Elbow, D60
  • Kyle Nelson (Diamondbacks): Back, D15
  • Humberto Castellanos (Diamondbacks): Elbow, D60
  • Ketel Marte (Diamondbacks): Hamstring, Day-to-Day
  • Nicholas Ahmed (Diamondbacks): Shoulder, D60
  • Alexander Reyes (Cardinals): Shoulder, D60
  • Steven Matz (Cardinals): Knee, D15
  • Jack Flaherty (Cardinals): Shoulder, D60
  • Drew VerHagen (Cardinals): Hip, D60

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.