• The Cardinals are -110 favorites vs the Diamondbacks
• Cardinals vs Diamondbacks Over / Under today: 9 Runs
• Cardinals / Diamondbacks TV Channel: CATV | DBTV

The St. Louis Cardinals (-110) visit Chase Field to take on the Arizona Diamondbacks (-110) on July 17, 2026. First pitch is scheduled for 9:40 pm in Phoenix, AZ.

This season, the Cardinals are 50-45 against the spread (ATS), while the Diamondbacks are 53-41 ATS.

Cardinals vs Diamondbacks Starting Pitchers Today:

• Cardinals starting pitcher: Michael McGreevy 4-7, 3.05 ERA
• Diamondbacks starting pitcher: Jose Cabrera 0-2, 5.51 ERA

Cardinals vs. Diamondbacks Odds, Run Line, Over/Under & Moneyline

Cardinals vs Diamondbacks Prediction for Today’s Game

Based on recent trends the model predicts the Diamondbacks will win Friday‘s MLB game with 52.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Cardinals players for Friday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Bets Today:

• Nathan Church has hit the Home Runs Over in 3 of his last 6 away games (+23.50 Units / 392% ROI)
• Ivan Herrera has hit the Total Bases Under in 20 of his last 25 games (+12.65 Units / 30% ROI)
• Blaze Jordan has hit the Runs Under in 14 of his last 15 games (+12.25 Units / 37% ROI)
• Jordan Walker has hit the Hits Runs and RBIs Over in 13 of his last 15 games (+10.45 Units / 58% ROI)
• Alec Burleson has hit the RBIs Over in 10 of his last 15 away games (+10.20 Units / 68% ROI)

And here are some favorite MLB player prop bets for Diamondbacks players for Friday‘s game, looking at profitable historical betting trends:

Best Diamondbacks Player Prop Best Bets Today:

• Gabriel Moreno has hit the Singles Over in 18 of his last 20 games (+15.30 Units / 58% ROI)
• Nolan Arenado has hit the Home Runs Over in 3 of his last 7 games (+14.40 Units / 206% ROI)
• Lourdes Gurriel Jr. has hit the Hits Under in 15 of his last 25 games at home (+13.50 Units / 47% ROI)
• Lourdes Gurriel Jr. has hit the Total Bases Under in 20 of his last 25 games at home (+12.80 Units / 32% ROI)
• Corbin Carroll has hit the RBIs Under in 17 of his last 20 games (+11.35 Units / 28% ROI)

Cardinals Best Bets Today:

• The St. Louis Cardinals have hit the Team Total Over in 28 of their last 40 away games (+14.40 Units / 30% ROI)
• The St. Louis Cardinals have covered the Run Line in 26 of their last 40 away games (+9.85 Units / 17% ROI)
• The St. Louis Cardinals have hit the Moneyline in 23 of their last 40 away games (+9.50 Units / 23% ROI)
• The St. Louis Cardinals have hit the Game Total Under in 27 of their last 45 games (+8.40 Units / 17% ROI)
• The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Over in 11 of their last 15 away games (+7.45 Units / 42% ROI)

Diamondbacks Best Bets Today:

• The Arizona Diamondbacks have hit the 1st Five Innings (F5) Team Total Under in 35 of their last 50 games at home (+17.55 Units / 29% ROI)
• The Arizona Diamondbacks have hit the Game Total Under in 31 of their last 50 games (+13.65 Units / 25% ROI)
• The Arizona Diamondbacks have hit the Moneyline in 6 of their last 9 games (+6.85 Units / 76% ROI)
• The Arizona Diamondbacks have covered the 1st Five Innings (F5) Run Line in 8 of their last 10 games at home (+6.05 Units / 51% ROI)
• The Arizona Diamondbacks have hit the 1st Five Innings (F5) Moneyline in 8 of their last 13 games (+5.95 Units / 42% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 55-38 against the Run Line (+5.45 Units / 4.01% ROI).

• 50-45 when betting on the Moneyline for +9.25 Units / 9.08% ROI
• 40-51 when betting on the total runs Over for -16.15 Units / -15.45% ROI
• 51-40 when betting on the total runs Under for +6.85 Units / 6.55% ROI

Diamondbacks Against the Spread (ATS) Record

Against the spread this season, the Diamondbacks are 53-41 against the Run Line (+3.5 Units / 2.69% ROI).

• 49-47 when betting on the Moneyline for +3.45 Units / 3.09% ROI
• 40-51 when betting on the total runs Over for -15.8 Units / -14.93% ROI
• 51-40 when betting on the total runs Under for +7.45 Units / 7.07% ROI

Diamondbacks vs Cardinals Home Run Prop Bets Today

Diamondbacks vs Cardinals Total Hits Prop Bets Today

Diamondbacks vs Cardinals Strikeout Prop Bets Today

Cardinals Keys to the Game vs. the Diamondbacks

The Cardinals were 18-9 (.667) when tied entering the 7th inning in the 2024 season — tied for 3rd best in MLB; League Avg: .498.

The Cardinals were 69-1 (.986) when leading entering the 9th inning in the 2024 season — tied for 2nd best in MLB; League Avg: .949.

The Cardinals were just 7-11 (.389) when tied entering the 8th inning in the 2025 season — tied for 5th lowest in MLB; League Avg: .500.

Diamondbacks Keys to the Game vs. the Cardinals

The Diamondbacks are 43-0 (1.000) when leading entering the 9th inning this season — tied for best in MLB; League Avg: .947.

The Diamondbacks are 17-4 (.810) when they’ve hit 2 or more home runs this season — tied for 5th best in MLB; League Avg: .699.

The Diamondbacks are 23-13 (.639) vs bottom 10 scoring offenses this season Today, they face the Cardinals (15th in runs scored).

The Diamondbacks are 17-4 (.810) when they’ve hit 2 or more home runs since the 2025 season — tied for 5th best in MLB; League Avg: .699.

Cardinals Hitting Stats & Trends

Cardinals hitters have struck out in just 17% of their PA’s against LHP this season — 2nd best in MLB.

Cardinals hitters are slugging just .366 at home this season — 3rd lowest in MLB.

Cardinals hitters have an OBP of just .305 (1,884 PA’s) at home this season — 3rd lowest in MLB.

Cardinals hitters have struck out in just 17% of their PA’s in lefty-lefty matchups this season — best in MLB.

Diamondbacks Hitting Stats & Trends

Diamondbacks hitters have struck out in just 17% of their PA’s against LHP this season — best in MLB.

9% of Diamondbacks’ hitters plate appearances have lasted only one pitch (324/3,577 PA’s) this season — lowest in MLB.

The Diamondbacks are batting .271 against LHP this season — best in MLB.

Diamondbacks hitters are slugging just .365 against RHP this season — lowest in MLB.

Cardinals Pitching Stats & Trends

Opponents have a miss rate of just 22% against Cardinals pitchers this season — lowest in MLB.

Opponents have a groundball rate of 46% against Cardinals pitchers this season — tied for highest in MLB.

Cardinals pitchers have a strikeout rate of just 39% with two-strikes this season — 4th lowest in MLB.

The Cardinals have won 50% of road games in which their opponents scored first this season — 2nd highest in MLB.

Diamondbacks Pitching Stats & Trends

Diamondbacks pitchers have a strikeout rate of just 18% this season — 2nd lowest in MLB.

Diamondbacks pitchers have struck out just 17% of left-handed batters they faced this season — lowest in MLB.

Diamondbacks pitchers have a strikeout rate of just 38% with two-strikes this season — 3rd lowest in MLB.

Diamondbacks pitchers have a strikeout rate of just 17% in the first 5 innings this season — 2nd lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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