Cardinals vs Giants Prediction, Odds & Player Prop Bets Today – MLB, Apr 27

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MLB betting odds, predictions and betting odds for today's games
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BetMGM Betting @BETMGM Apr 27, 2023, 3:31 PM
  • The Giants are -160 favorites vs the Cardinals
  • Cardinals starting pitcher: Miles Mikolas
  • Giants starting pitcher: Logan Webb
  • Watch the game on MLB Network

The St. Louis Cardinals (+135) visit Oracle Park to take on the San Francisco Giants (-160) on Thursday, April 27, 2023. First pitch is scheduled for 3:45pm EDT in San Francisco.

The Giants are the betting favorite in this game, with the run line sitting at -1.5 (+125).

The Cardinals vs Giants Over/Under is 8.5 total runs for the game.

This season, the Cardinals are 9-16 against the spread (ATS), while the Giants are 12-12 ATS.

Cardinals vs. Giants Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cardinals+1.5 -150O 8.5 -110+135
Giants -1.5 +125U 8.5 -110-160

Cardinals vs Giants Prediction for Today’s Game

Based on recent trends the model predicts the Giants will win Thursday‘s MLB matchup with 51.9% confidence.

This prediction factors in starting pitchers, recent team and player hitting performances, the last 5 games for both the Cardinals and Giants and up-to-date player injuries.


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We’ve highlighted some favorite MLB player prop bets for Cardinals players for Thursday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Bets Today:

  • Nolan Gorman has hit the Runs Under in 13 of his last 15 games (+10.70 Units / 40% ROI)
  • Nolan Arenado has hit the RBIs Under in 15 of his last 19 games (+8.65 Units / 25% ROI)
  • Brendan Donovan has hit the Hits Under in 7 of his last 8 away games (+8.30 Units / 74% ROI)
  • Alec Burleson has hit the Hits Runs and RBIs Under in 12 of his last 16 games (+7.75 Units / 44% ROI)
  • Nolan Arenado has hit the Total Bases Under in his last 7 games (+7.00 Units / 63% ROI)

And here are some favorite MLB player prop bets for Giants players for Thursday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Best Bets Today:

  • David Villar has hit the Singles Under in his last 12 games (+12.00 Units / 48% ROI)
  • Thairo Estrada has hit the Runs Over in 13 of his last 19 games (+10.90 Units / 57% ROI)
  • Thairo Estrada has hit the Hits Over in 16 of his last 22 games (+10.60 Units / 27% ROI)
  • Thairo Estrada has hit the Singles Over in 17 of his last 22 games (+9.45 Units / 30% ROI)
  • Mike Yastrzemski has hit the Total Bases Over in 15 of his last 20 games (+8.60 Units / 29% ROI)

Giants vs Cardinals Home Run Prop Bets Today

Over Under
Nolan Arenado 0.5 +650 0.5 -2000
Nolan Gorman 0.5 +600 0.5 -1600
Brandon Crawford 0.5 +850 0.5 -5000
Mike Yastrzemski 0.5 +575 0.5 -1400
Tommy Edman 0.5 +1100 0.5

Giants vs Cardinals Total Hits Prop Bets Today

Over Under
Nolan Arenado 0.5 -250 0.5 +195
Nolan Gorman 0.5 -225 0.5 +175
Brandon Crawford 0.5 -150 0.5 +115
Mike Yastrzemski 0.5 -185 0.5 +140
Tommy Edman 0.5 -210 0.5 +160

Giants vs Cardinals RBI Prop Bets Today

Over Under
Nolan Arenado 0.5 +160 0.5 -210
Nolan Gorman 0.5 +170 0.5 -225
Brandon Crawford 0.5 +250 0.5 -350
Mike Yastrzemski 0.5 +190 0.5 -250
Tommy Edman 0.5 +230 0.5 -350

Giants vs Cardinals Strikeout Prop Bets Today

Over Under
Logan Webb 5.5 -105 5.5 -125
Miles Mikolas 4.5 -115 4.5 -110
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 16 of their last 21 games (+10.85 Units / 43% ROI)
  • The St. Louis Cardinals have hit the Team Total Under in 14 of their last 21 games (+5.75 Units / 23% ROI)
  • The St. Louis Cardinals have hit the Game Total Under in 8 of their last 12 away games (+3.70 Units / 29% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 3 of their last 7 away games (+1.25 Units / 15% ROI)
  • The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 4 of their last 7 away games (+1.15 Units / 15% ROI)
  • The San Francisco Giants have hit the Team Total Over in 11 of their last 14 games (+8.20 Units / 51% ROI)
  • The San Francisco Giants have covered the Run Line in their last 5 games (+5.60 Units / 73% ROI)
  • The San Francisco Giants have covered the 1st Five Innings (F5) Run Line in 10 of their last 14 games (+5.50 Units / 31% ROI)
  • The San Francisco Giants have hit the Moneyline in their last 5 games (+5.05 Units / 89% ROI)
  • The San Francisco Giants have hit the 1st Five Innings (F5) Moneyline in 4 of their last 5 games (+4.00 Units / 67% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this MLB season, the Cardinals have gone 10-15 against the Run Line (-6.5 Units / -21.59% ROI).

  • 9-16 when betting on the Moneyline for -11.75 Units / -34.26% ROI
  • 11-13 when betting on the total runs Over for -3.4 Units / -12.39% ROI
  • 13-11 when betting on the total runs Under for +0.75 Units / 2.72% ROI

Giants Against the Spread (ATS) Record

Against the spread this MLB season, the Giants have gone 12-12 against the Run Line (-2.3 Units / -6.62% ROI).

  • 11-13 when betting on the Moneyline for -4.1 Units / -14.51% ROI
  • 12-11 when betting on the total runs Over for -0.25 Units / -0.93% ROI
  • 11-12 when betting on the total runs Under for -2 Units / -7.68% ROI

Right-handed hitters have a miss rate of just 12% (15/126) against Miles Mikolas this season — lowest among qualified SPs in MLB; League Avg: 26% — first Percentile.

Opponents are hitting .339 (19-for-56) against Miles Mikolas with two-strikes this season — highest among qualified SPs in MLB; League Avg: .167 — first Percentile.

Miles Mikolas has allowed an OPS of .920 (60 PA’s) with two-strikes this season — highest among qualified SPs in MLB; League Avg: .497 — first Percentile.

Left-handed hitters have a groundball rate of just 21% (8/38) against Miles Mikolas this season — lowest among qualified SPs in MLB; League Avg: 44% — first Percentile.

Giants Starting Pitcher Stats & Trends

Right-handed hitters have a groundball rate of 86% (18/21) against Logan Webb — highest in MLB over the last two weeks; League Avg: 44% — 100th Percentile.

Logan Webb has thrown low pitches 72% of the time (557/768) with runners in scoring position since last season — highest among qualified SPs in MLB; League Avg: 48% — 100th Percentile.

Right-handed hitters have a groundball rate of 64% (27/42) against Logan Webb this season — 2nd highest among qualified SPs in MLB; League Avg: 44% — 98th Percentile.

Left-handed hitters have a groundball rate of 56% (22/39) against Logan Webb this season — 8th highest among qualified SPs in MLB; League Avg: 44% — 88th Percentile.

Cardinals Keys to the Game vs. the Giants

The Cardinals are 19-4 (.826) when tied entering the 8th inning since the 2022 season — best in MLB; League Avg: .500.

The Cardinals are just 0-14 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .098.

The Cardinals are 28-10 (.737) when tied entering the 8th inning since the 2021 season — best in MLB; League Avg: .500.

The Cardinals are just 6-2 (.750) when leading entering the 8th inning this season — 2nd lowest in MLB; League Avg: .902.

Giants Keys to the Game vs. the Cardinals

The Giants are 53-61 (.465) when allowing 10 or more hits since the 2021 season — best in MLB; League Avg: .266.

The Giants are 1-10 (.091) when trailing entering the 9th inning this season — tied for 3rd best in MLB; League Avg: .038.

The Giants are just 13-31 (.295) when moneyline underdogs of less than +150 since the 2022 season — 3rd lowest in MLB; League Avg: .416.

The Giants are 74-2 (.974) when leading entering the 9th inning since the 2022 season — tied for 5th best in MLB; League Avg: .955.

Cardinals hitters have an OPS of .938 (163 PA’s) against LHP this season — best in MLB; League Avg: .731.

Cardinals hitters are slugging .555 against LHP this season — best in MLB; League Avg: .408.

Cardinals hitters have an OPS of .822 (1,526 PA’s) against LHP since last season — best in MLB; League Avg: .716.

Cardinals hitters are slugging .871 on the first pitch of at-bats this season — 2nd best in MLB; League Avg: .587.

Giants hitters have 103 strikeouts in 344 PA’s (30%) against LHP this season — 2nd highest in MLB; League Avg: 23%.

Giants hitters have 256 strikeouts in 931 PA’s (28%) this season — highest in MLB; League Avg: 23%.

The Giants are batting just .223 when facing the starting pitcher for the 3rd time in a game since last season — lowest in MLB; League Avg: .264.

The Giants are batting .369 on the first pitch of at-bats since last season — best in MLB; League Avg: .338.

Opponents have a groundball rate of 47% against Cardinals pitchers since last season — 2nd highest in MLB; League Avg: 43%.

Cardinals pitchers have a strikeout rate of just 39% with two-strikes since last season — 5th lowest in MLB; League Avg: 42%.

Cardinals pitchers have a strikeout rate of just 17% with runners in scoring position since last season — lowest in MLB; League Avg: 21%.

Opponents had a groundball rate of 47% against Cardinals pitchers in 2022 — 2nd highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 49% against Giants pitchers since last season — highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 51% against Giants pitchers this season — highest in MLB; League Avg: 43%.

Giants pitchers have walked 61 of 919 batters (7%) this season — best in MLB; League Avg: 9%.

Opponents had a groundball rate of 48% against Giants pitchers in 2022 — highest in MLB; League Avg: 43%.

Giants vs. Cardinals Injuries Tonight That May Affect Prop Bets 

  • Robert Wood (Giants): Hamstring, D15
  • Roberto Pérez (Giants): Shoulder, D60
  • Darin Ruf (Giants): Wrist, D10
  • Luke Jackson (Giants): Elbow, D60
  • Austin Slater (Giants): Elbow, D10
  • Mitchell Haniger (Giants): Oblique, D10
  • Bryce Johnson (Giants): Concussion, D7
  • Luis González (Giants): Back, D60
  • Joseph Bart (Giants): Groin, Day-to-Day
  • Thomas Szapucki (Giants): Left Arm, D60
  • Patrick Naughton (Cardinals): Forearm, D15
  • Adam Wainwright (Cardinals): Groin, D15
  • Wilking Rodríguez (Cardinals): Shoulder, D15

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.