Cardinals vs Mariners Prediction, Odds & Player Prop Bets Today – MLB, Apr 22

min read
MLB betting odds, predictions and betting odds for today's games
(AP Photo)
BetMGM Betting @BETMGM Apr 22, 2023, 3:32 PM
  • The Mariners are -160 favorites vs the Cardinals
  • Cardinals starting pitcher: Miles Mikolas
  • Mariners starting pitcher: Luis Castillo
  • Watch the game on ROOT Sports NW

The St. Louis Cardinals (+135) visit T-Mobile Park to take on the Seattle Mariners (-160) on Saturday, April 22, 2023. First pitch is scheduled for 9:40pm EDT in Seattle.

The Mariners are the betting favorite in this game, with the run line sitting at -1.5 (+130).

The Cardinals vs Mariners Over/Under is 7.5 total runs for the game.

This season, the Cardinals are 8-12 against the spread (ATS), while the Mariners are 9-11 ATS.

Cardinals vs. Mariners Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cardinals+1.5 -155O 7.5 +100+135
Mariners -1.5 +130U 7.5 -120-160

Cardinals vs Mariners Prediction for Today’s Game

Based on recent trends the model predicts the Mariners will win Saturday‘s MLB matchup with 51.9% confidence.

This prediction factors in starting pitchers, recent team and player hitting performances, the last 5 games for both the Cardinals and Mariners and up-to-date player injuries.


Bet now on Cardinals vs Mariners and all games with BetMGM


We’ve highlighted some favorite MLB player prop bets for Cardinals players for Saturday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Bets Today:

  • Nolan Arenado has hit the RBIs Under in 12 of his last 15 games (+8.20 Units / 31% ROI)
  • Nolan Gorman has hit the Runs Under in 9 of his last 10 games (+8.00 Units / 45% ROI)
  • Tommy Edman has hit the Hits Runs and RBIs Under in 12 of his last 16 games (+7.60 Units / 36% ROI)
  • Nolan Arenado has hit the Singles Over in 14 of his last 19 games (+7.45 Units / 33% ROI)
  • Tommy Edman has hit the Runs Under in 12 of his last 16 games (+6.60 Units / 21% ROI)

And here are some favorite MLB player prop bets for Mariners players for Saturday‘s game, looking at profitable historical betting trends:

Best Mariners Player Prop Best Bets Today:

  • Ty France has hit the Runs Over in 14 of his last 20 games (+12.15 Units / 61% ROI)
  • Julio Rodriguez has hit the Runs Over in 14 of his last 17 games (+10.85 Units / 56% ROI)
  • Ty France has hit the Hits Runs and RBIs Over in 15 of his last 20 games (+10.45 Units / 44% ROI)
  • Kolten Wong has hit the Total Bases Under in 11 of his last 14 games (+9.50 Units / 66% ROI)
  • Kolten Wong has hit the Hits Under in 11 of his last 14 games (+9.35 Units / 65% ROI)

Mariners vs Cardinals Home Run Prop Bets Today

Over Under
Teoscar Hernandez 0.5 +360 0.5 -650
Nolan Arenado 0.5 +475 0.5 -1000
Nolan Gorman 0.5 +400 0.5 -750
Tommy La Stella 0.5 +650 0.5 -2000
J.P. Crawford 0.5 +850 0.5 -5000

Mariners vs Cardinals Total Hits Prop Bets Today

Over Under
Teoscar Hernandez 0.5 -250 0.5 +175
Nolan Arenado 0.5 -210 0.5 +160
Nolan Gorman 0.5 -130 0.5 +100
Tommy La Stella 0.5 -145 0.5 +110
J.P. Crawford 0.5 -145 0.5 +110

Mariners vs Cardinals RBI Prop Bets Today

Over Under
Teoscar Hernandez 0.5 +170 0.5 -225
Nolan Arenado 0.5 +185 0.5 -250
Nolan Gorman 0.5 +220 0.5 -300
Tommy La Stella 0.5 +250 0.5 -350
J.P. Crawford 0.5 +270 0.5 -375

Mariners vs Cardinals Strikeout Prop Bets Today

Over Under
Luis Castillo 6.5 -110 6.5 -120
Miles Mikolas 4.5 -135 4.5 +105
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 13 of their last 16 games (+10.40 Units / 56% ROI)
  • The St. Louis Cardinals have hit the Team Total Under in 11 of their last 16 games (+5.40 Units / 29% ROI)
  • The St. Louis Cardinals have hit the Game Total Under in 6 of their last 7 away games (+4.95 Units / 66% ROI)
  • The Seattle Mariners have hit the 1st Five Innings (F5) Moneyline in 5 of their last 8 games (+4.00 Units / 29% ROI)
  • The Seattle Mariners have hit the 1st Five Innings (F5) Team Total Over in 7 of their last 11 games at home (+3.10 Units / 24% ROI)
  • The Seattle Mariners have hit the Team Total Over in 6 of their last 9 games at home (+2.95 Units / 27% ROI)
  • The Seattle Mariners have hit the Game Total Under in 5 of their last 8 games (+1.80 Units / 21% ROI)
  • The Seattle Mariners have covered the Run Line in 5 of their last 9 games at home (+1.05 Units / 10% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this MLB season, the Cardinals have gone 8-12 against the Run Line (-5.9 Units / -23.98% ROI).

  • 8-12 when betting on the Moneyline for -8.55 Units / -29.53% ROI
  • 8-11 when betting on the total runs Over for -4.05 Units / -18.62% ROI
  • 11-8 when betting on the total runs Under for +2 Units / 8.97% ROI

Mariners Against the Spread (ATS) Record

Against the spread this MLB season, the Mariners have gone 9-11 against the Run Line (-2.35 Units / -9.36% ROI).

  • 9-11 when betting on the Moneyline for -5.15 Units / -17.64% ROI
  • 10-9 when betting on the total runs Over for +0 Units / 0% ROI
  • 9-10 when betting on the total runs Under for -1.95 Units / -8.97% ROI

Opponents have a line drive rate of 40% (30/75) against Miles Mikolas this season — highest among qualified SPs in MLB; League Avg: 23% — first Percentile.

Opponents are hitting .396 (36-for-91) against Miles Mikolas this season — highest among qualified SPs in MLB; League Avg: .243 — first Percentile.

Opponents are hitting .356 (16-for-45) against Miles Mikolas with two-strikes this season — highest among qualified SPs in MLB; League Avg: .170 — first Percentile.

Miles Mikolas has allowed a slugging percentage of .533 (24 Total Bases / 45 ABs) with two-strikes this season — 2nd highest among qualified SPs in MLB; League Avg: .260 — second Percentile.

Mariners Starting Pitcher Stats & Trends

Luis Castillo has allowed an OBP of just .170 (88 PA’s) this season — best among qualified SPs in MLB; League Avg: .311 — 100th Percentile.

Luis Castillo has allowed an OPS of just .337 (88 PA’s) this season — best among qualified SPs in MLB; League Avg: .709 — 100th Percentile.

Luis Castillo has a strikeout rate of 57% (12 SO in 21 PAs) in PAs ending on elevated fastballs this season — best among qualified SPs in MLB; League Avg: 25% — 100th Percentile.

Opponents are hitting just .103 (6-for-58) against Luis Castillo on pitches in the strike zone this season — best among qualified SPs in MLB; League Avg: .279 — 100th Percentile.

Cardinals Keys to the Game vs. the Mariners

The Cardinals are 28-10 (.737) when tied entering the 8th inning since the 2021 season — best in MLB; League Avg: .500.

The Cardinals are 25-35 (.417) when allowing 10 or more hits since the 2022 season — best in MLB; League Avg: .270.

The Cardinals are just 0-10 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .037.

The Cardinals are 38-5 (.884) when totaling 5 or more extra base hits since the 2022 season — 4th best in MLB; League Avg: .806.

Mariners Keys to the Game vs. the Cardinals

The Mariners are just 0-7 (.000) when trailing entering the 7th inning this season — tied for lowest in MLB; League Avg: .129.

The Mariners are 76-2 (.974) when leading entering the 8th inning since the 2022 season — best in MLB; League Avg: .914.

The Mariners are just 0-8 (.000) when allowing 5 or more runs this season — tied for lowest in MLB; League Avg: .207.

The Mariners are 34-13 (.723) when tied entering the 8th inning since the 2021 season — 2nd best in MLB; League Avg: .500.

Cardinals hitters are slugging .556 against LHP this season — 2nd best in MLB; League Avg: .404.

Cardinals hitters have an OPS of .939 (142 PA’s) against LHP this season — best in MLB; League Avg: .728.

Cardinals hitters are slugging .474 against LHP since last season — best in MLB; League Avg: .399.

Cardinals hitters have an OPS of .811 (2,750 PA’s) against LHP since the 2021 season — best in MLB; League Avg: .725.

The Mariners are batting just .305 on the first pitch of at-bats since the 2020 season — lowest in MLB; League Avg: .340.

Mariners hitters are slugging just .170 on pitches out of the zone since the 2021 season — 2nd lowest in MLB; League Avg: .210.

Mariners hitters are slugging just .172 on pitches out of the zone since the 2020 season — 3rd lowest in MLB; League Avg: .210.

Mariners hitters have chased 25% of pitches out of the zone against LHP since last season — lowest in MLB; League Avg: 29%.

Opponents have a groundball rate of 48% against Cardinals pitchers since last season — 2nd highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 48% against Cardinals pitchers this season — 2nd highest in MLB; League Avg: 43%.

Opponents had a groundball rate of 47% against Cardinals pitchers in 2022 — 2nd highest in MLB; League Avg: 43%.

Cardinals pitchers have a strikeout rate of just 39% with two-strikes since last season — tied for 4th lowest in MLB; League Avg: 42%.

Opponents have a groundball rate of 47% against Mariners pitchers this season — 3rd highest in MLB; League Avg: 43%.

Opponents have a groundball rate of just 41% against Mariners pitchers since the 2020 season — 2nd lowest in MLB; League Avg: 44%.

Opponents have a groundball rate of just 41% against Mariners pitchers since last season — 3rd lowest in MLB; League Avg: 43%.

Mariners pitchers have walked 11 of 217 batters (5%) over the past seven days (6 games) — 2nd best in MLB; League Avg: 9%.

Mariners vs. Cardinals Injuries Tonight That May Affect Prop Bets 

  • Taylor Trammell (Mariners): Hand, D10
  • Samuel Haggerty (Mariners): Concussion, D7
  • Andrés Muñoz (Mariners): Deltoid, D15
  • Robert Ray (Mariners): Flexor, D15
  • Dylan Moore (Mariners): Olique, D10
  • Evan White (Mariners): Adductor, D60
  • Patrick Naughton (Cardinals): Forearm, D15
  • Adam Wainwright (Cardinals): Groin, D15
  • Paul DeJong (Cardinals): Back, D10
  • Wilking Rodríguez (Cardinals): Shoulder, D15

Bet now on Cardinals vs Mariners and all games with BetMGM


Bet on MLB Odds at BetMGM

At BetMGM, you can bet online with updated MLB betting odds. And with live sports betting, the best online sports betting and mobile sports betting (with the BetMGM Sportsbook app) experiences are at BetMGM.

BetMGM first bet offer for $1000
About the Author

BetMGM Betting

Read More @BETMGM

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.