• The Reds are -155 favorites vs the Cardinals
• Cardinals vs Reds Over / Under today: 8.5 Runs
• Cardinals / Reds TV Channel: CATV | RDTV

The St. Louis Cardinals (+125) visit Great American Ball Park to take on the Cincinnati Reds (-155) on August 19, 2026. First pitch is scheduled for 6:40 pm in Cincinnati, OH.

This season, the Cardinals are 65-62 against the spread (ATS), while the Reds are 65-59 ATS.

Cardinals vs Reds Starting Pitchers Today:

• Cardinals starting pitcher: Matthew Liberatore 5-10, 5.09 ERA
• Reds starting pitcher: Chase Burns 14-2, 2.48 ERA

Cardinals vs. Reds Odds, Run Line, Over/Under & Moneyline

Cardinals vs Reds Prediction for Today’s Game

Based on recent trends the model predicts the Reds will win Wednesday‘s MLB game with 54.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Cardinals vs Reds and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Cardinals players for Wednesday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Bets Today:

• Alec Burleson has hit the Total Bases Over in 17 of his last 25 away games (+11.20 Units / 43% ROI)
• Alec Burleson has hit the Hits Over in 14 of his last 20 away games (+10.15 Units / 31% ROI)
• Nathan Church has hit the Hits Runs and RBIs Over in 14 of his last 20 games (+9.20 Units / 39% ROI)
• Alec Burleson has hit the Home Runs Over in 3 of his last 8 away games (+8.80 Units / 110% ROI)
• JJ Wetherholt has hit the Walks Over in 7 of his last 10 away games (+7.95 Units / 80% ROI)

And here are some favorite MLB player prop bets for Reds players for Wednesday‘s game, looking at profitable historical betting trends:

Best Reds Player Prop Best Bets Today:

• JJ Bleday has hit the RBIs Under in 14 of his last 15 games (+12.25 Units / 41% ROI)
• Ke’Bryan Hayes has hit the Home Runs Over in 2 of his last 7 games at home (+12.00 Units / 171% ROI)
• Eugenio Suarez has hit the Runs Under in 20 of his last 25 games at home (+11.70 Units / 28% ROI)
• Ke’Bryan Hayes has hit the Hits Runs and RBIs Under in 19 of his last 25 games at home (+11.65 Units / 33% ROI)
• Sal Stewart has hit the Singles Over in 18 of his last 25 games (+10.25 Units / 35% ROI)

Cardinals Best Bets Today:

• The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 27 of their last 50 away games (+14.75 Units / 28% ROI)
• The St. Louis Cardinals have hit the Game Total Under in 31 of their last 50 games (+12.40 Units / 23% ROI)
• The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 33 of their last 50 away games (+11.90 Units / 20% ROI)
• The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 23 of their last 35 games (+9.10 Units / 21% ROI)
• The St. Louis Cardinals have hit the Moneyline in 11 of their last 16 games (+8.65 Units / 47% ROI)

Reds Best Bets Today:

• The Cincinnati Reds have hit the Team Total Under in 28 of their last 40 games at home (+14.35 Units / 31% ROI)
• The Cincinnati Reds have hit the 1st Five Innings (F5) Team Total Under in 26 of their last 40 games at home (+9.80 Units / 20% ROI)
• The Cincinnati Reds have hit the Game Total Under in 22 of their last 35 games at home (+9.10 Units / 24% ROI)
• The Cincinnati Reds have hit the 1st Five Innings (F5) Moneyline in 10 of their last 21 games at home (+5.20 Units / 20% ROI)
• The Cincinnati Reds have covered the 1st Five Innings (F5) Run Line in 13 of their last 21 games at home (+3.30 Units / 13% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 69-55 against the Run Line (-0.45 Units / -0.25% ROI).

• 65-62 when betting on the Moneyline for +8.8 Units / 6.38% ROI
• 51-70 when betting on the total runs Over for -26.35 Units / -18.82% ROI
• 70-51 when betting on the total runs Under for +13.75 Units / 9.86% ROI

Reds Against the Spread (ATS) Record

Against the spread this season, the Reds are 65-59 against the Run Line (-10 Units / -5.67% ROI).

• 60-66 when betting on the Moneyline for -5.65 Units / -4% ROI
• 65-59 when betting on the total runs Over for +0 Units / 0% ROI
• 59-65 when betting on the total runs Under for -11.95 Units / -8.66% ROI

Reds vs Cardinals Home Run Prop Bets Today

Reds vs Cardinals Total Hits Prop Bets Today

Reds vs Cardinals Strikeout Prop Bets Today

Cardinals Keys to the Game vs. the Reds

The Cardinals are 7-3 (.700) this season — tied for 3rd best in MLB.

The Cardinals are 7-3 (.700) since the 2025 season — tied for 3rd best in MLB.

The Cardinals were 18-9 (.667) when tied entering the 7th inning in the 2024 season — tied for 3rd best in MLB; League Avg: .498.

The Cardinals were 69-1 (.986) when leading entering the 9th inning in the 2024 season — tied for 2nd best in MLB; League Avg: .949.

Reds Keys to the Game vs. the Cardinals

The Reds are just 0-6 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB.

The Reds are just 0-6 (.000) when trailing entering the 9th inning since the 2025 season — tied for lowest in MLB.

The Reds were just 5-16 (.238) when tied entering the 8th inning in the 2024 season — lowest in MLB; League Avg: .500.

The Reds were just 7-50 (.123) when they allowed 5 or more runs in the 2025 season — 3rd lowest in MLB; League Avg: .202.

Cardinals Hitting Stats & Trends

Cardinals hitters have struck out in just 18% of their PA’s against LHP this season — tied for 2nd best in MLB.

Cardinals hitters have an OBP of .325 (2,397 PA’s) on the road this season — 5th best in MLB.

Cardinals hitters have an OBP of just .307 (2,411 PA’s) at home this season — tied for 2nd lowest in MLB.

Cardinals hitters are slugging just .362 at home this season — 2nd lowest in MLB.

Reds Hitting Stats & Trends

Reds hitters have struck out in 26% of their PA’s against RHP this season — highest in MLB.

The Reds are batting just .206 with two outs this season — lowest in MLB.

The Reds are batting just .219 with runners on base this season — lowest in MLB.

The Reds are batting just .116 on pitches out of the zone this season — lowest in MLB.

Cardinals Pitching Stats & Trends

The Cardinals pitchers have allowed their opponents to score first in just 33% of their games on the road this season — lowest in MLB.

Opponents have a groundball rate of 46% against Cardinals pitchers this season — 3rd highest in MLB.

Cardinals pitchers have induced opposing hitters to ground into 112 double plays in 947 opportunities (12%) this season — best in MLB.

Opponents have a miss rate of just 23% against Cardinals pitchers this season — 4th lowest in MLB.

Reds Pitching Stats & Trends

Reds pitchers have walked 11% of batters this season — 3rd highest in MLB.

The Reds pitchers have allowed their opponents to score first in 59% of their games this season — 2nd highest in MLB.

The Reds pitchers have allowed their opponents to score first in 65% of their games at home this season — 2nd highest in MLB.

The Reds pitchers have allowed their opponents to score first in 53% of their games on the road this season — 4th highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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