Chicago Cubs vs Houston Astros Prediction, Odds & Player Prop Bets Today – MLB, Jun 27

  • The Chicago Cubs are -105 favorites vs the Houston Astros
  • Chicago Cubs vs Houston Astros Over / Under today: 8.5 Runs
  • Chicago Cubs / Houston Astros TV Channel: MARQ | SCHN | SCH2

The Chicago Cubs (-105) visit Daikin Park to take on the Houston Astros (-115) on Friday, June 27, 2025. First pitch is scheduled for 8:10pm EDT in Houston, TX.

This season, the Chicago Cubs are 48-33 against the spread (ATS), while the Houston Astros are 41-40 ATS.

Chicago Cubs vs Houston Astros Starting Pitchers Today:

  • Chicago Cubs starting pitcher: , ERA
  • Houston Astros starting pitcher: , ERA

Chicago Cubs vs. Houston Astros Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Chicago Cubs-1.5 +155O 8.5 -115-105
Houston Astros +1.5 -190U 8.5 -105-115

Chicago Cubs vs Houston Astros Prediction for Today’s Game

Based on recent trends the model predicts the will win Friday‘s MLB game with confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Chicago Cubs players for Friday‘s game, looking at profitable historical betting trends:

Best Chicago Cubs Player Prop Bets Today:

  • Nico Hoerner has hit the Home Runs Over in 1 of his last 4 games (+13.00 Units / 325% ROI)
  • Seiya Suzuki has hit the Runs Under in 18 of his last 25 games (+9.40 Units / 27% ROI)
  • Dansby Swanson has hit the Hits Over in 19 of his last 25 away games (+8.85 Units / 19% ROI)
  • Justin Turner has hit the Hits Runs and RBIs Under in 12 of his last 15 games (+8.60 Units / 41% ROI)
  • Dansby Swanson has hit the Singles Over in 16 of his last 25 away games (+8.30 Units / 31% ROI)

And here are some favorite MLB player prop bets for Houston Astros players for Friday‘s game, looking at profitable historical betting trends:

Best Houston Astros Player Prop Best Bets Today:

  • Cooper Hummel has hit the Home Runs Over in 2 of his last 6 games (+16.00 Units / 267% ROI)
  • Jeremy Pena has hit the Hits Over in 17 of his last 25 games at home (+15.60 Units / 42% ROI)
  • Jake Meyers has hit the Singles Over in 18 of his last 25 games (+10.20 Units / 35% ROI)
  • Jeremy Pena has hit the Total Bases Over in 16 of his last 25 games at home (+9.65 Units / 38% ROI)
  • Jeremy Pena has hit the Hits Runs and RBIs Over in 18 of his last 25 games at home (+8.55 Units / 25% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 41 of their last 79 games (+12.35 Units / 11% ROI)
  • The Chicago Cubs have hit the Moneyline in 46 of their last 75 games (+10.95 Units / 10% ROI)
  • The Chicago Cubs have hit the Game Total Under in 17 of their last 28 games (+7.25 Units / 24% ROI)
  • The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 43 of their last 77 games (+5.70 Units / 6% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Over in 7 of their last 9 games (+5.20 Units / 54% ROI)
  • The Houston Astros have hit the Moneyline in 27 of their last 35 games at home (+17.45 Units / 36% ROI)
  • The Houston Astros have hit the Team Total Under in 50 of their last 81 games (+15.75 Units / 17% ROI)
  • The Houston Astros have hit the Game Total Under in 30 of their last 48 games (+11.65 Units / 22% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 24 of their last 38 games at home (+8.10 Units / 18% ROI)
  • The Houston Astros have covered the Run Line in 21 of their last 37 games at home (+7.52 Units / 17% ROI)

Chicago Cubs Against the Spread (ATS) Record

Against the spread this season, the Chicago Cubs are 40-41 against the Run Line (-0.23 Units / -0.24% ROI).

  • 48-33 when betting on the Moneyline for +8.85 Units / 7.44% ROI
  • 41-35 when betting on the total runs Over for +2.95 Units / 3.33% ROI
  • 35-41 when betting on the total runs Under for -10.15 Units / -11.32% ROI

Houston Astros Against the Spread (ATS) Record

Against the spread this season, the Houston Astros are 41-40 against the Run Line (+2.22 Units / 2.2% ROI).

  • 48-33 when betting on the Moneyline for +8.65 Units / 8.13% ROI
  • 32-46 when betting on the total runs Over for -18.05 Units / -20.38% ROI
  • 46-32 when betting on the total runs Under for +10.9 Units / 12.14% ROI

Houston Astros vs Chicago Cubs Home Run Prop Bets Today

Over Under
Seiya Suzuki (CHC) 0.5 +375 0.5 -525
Christian Walker (HOU) 0.5 +375 0.5 -525
Kyle Tucker (CHC) 0.5 +425 0.5 -625
Ian Happ (CHC) 0.5 +500 0.5 -700
Isaac Paredes (HOU) 0.5 +500 0.5 -700

Houston Astros vs Chicago Cubs Total Hits Prop Bets Today

Over Under
Seiya Suzuki (CHC) 0.5 -275 0.5 +200
Kyle Tucker (CHC) 0.5 -250 0.5 +190
Nico Hoerner (CHC) 0.5 -250 0.5 +195
Cam Smith (HOU) 0.5 -235 0.5 +175
Jose Altuve (HOU) 0.5 -225 0.5 +175

Houston Astros vs Chicago Cubs RBI Prop Bets Today

Over Under
Seiya Suzuki (CHC) 0.5 +145 0.5 -190
Yainer Diaz (HOU) 0.5 +145 0.5 -190
Dansby Swanson (CHC) 0.5 +150 0.5 -200
Kyle Tucker (CHC) 0.5 +165 0.5 -220
Christian Walker (HOU) 0.5 +170 0.5 -225

Houston Astros vs Chicago Cubs Strikeout Prop Bets Today

Over Under
Cade Horton (CHC) 3.5 -165 3.5 +130
Brandon Walter (HOU) 4.5 +130 4.5 -175
Cade Horton (CHC) 4.5 +130 4.5 -165

starting pitcher – away

Houston Astros Starting Pitcher Stats & Trends

starting pitcher – home

Chicago Cubs Keys to the Game vs. the Houston Astros

keys to the game – away

Houston Astros Keys to the Game vs. the Chicago Cubs

keys to the game – home

team hitters – away

team hitters – home

team pitchers – away

team pitchers – home

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.